Moraes, Carlos T.

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

Fünfschilling, U., Supplie, L. M., Mahad, D., Boretius, S., Saab, A. S., Edgar, J., Brinkmann, B. G., Kassmann, C. M., Tzvetanova, I. D., Möbius, W., et al. (2012) · Nature

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 1,523

RETRACTED: Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

Wenz, T., Rossi, S. G., Rotundo, R. L., Spiegelman, B. M., & Moraes, C. T. (2009) · Proceedings of the National Academy of Sciences

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 600

The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

Bell, E. L., Klimova, T. A., Eisenbart, J., Moraes, C. T., Murphy, M. P., Budinger, G. R. S., & Chandel, N. S. (2007) · The Journal of Cell Biology

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 568

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs

Bacman, S. R., Williams, S. L., Pinto, M., Peralta, S., & Moraes, C. T. (2013) · Nature Medicine

CRISPR and Genetic EngineeringMitochondrial Function and Pathology

Cited by 432

Mitochondrial myopathy induces a starvation-like response

Tyynismaa, H., Carroll, C. J., Raimundo, N., Ahola-Erkkilä, S., Wenz, T., Ruhanen, H., Guse, K., Hemminki, A., Peltola-Mjøsund, K. E., Tulkki, V., et al. (2010) · Human Molecular Genetics

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 300

RETRACTED: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype

Wenz, T., Diaz, F., Spiegelman, B. M., & Moraes, C. T. (2008) · Cell Metabolism

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 297

Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease

Fukui, H., Diaz, F., Garcia, S., & Moraes, C. T. (2007) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 185

Respiration-Deficient Astrocytes Survive As Glycolytic Cells In Vivo

Supplie, L. M., Düking, T., Campbell, G., Diaz, F., Moraes, C. T., Götz, M., Hamprecht, B., Boretius, S., Mahad, D., & Nave, K.-A. (2017) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchMitochondrial Function and Pathology

Cited by 153

The role of PGC‐1 coactivators in aging skeletal muscle and heart

Dillon, L. M., Rebelo, A. P., & Moraes, C. T. (2012) · IUBMB Life

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 116

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels

Peralta, S., Goffart, S., Williams, S. L., Diaz, F., Garcia, S., Nissanka, N., Area-Gomez, E., Pohjoismäki, J., & Moraes, C. T. (2018) · Journal of Cell Science

Mitochondrial Function and PathologyATP Synthase and ATPases Research

Cited by 110

Overexpression of PGC ‐1α in aging muscle enhances a subset of young‐like molecular patterns

Garcia, S., Nissanka, N., Mareco, E. A., Rossi, S., Peralta, S., Diaz, F., Rotundo, R. L., Carvalho, R. F., & Moraes, C. T. (2018) · Aging Cell

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 81

Endurance exercise is protective for mice with mitochondrial myopathy

Wenz, T., Diaz, F., Hernandez, D., & Moraes, C. T. (2009) · Journal of Applied Physiology

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 78

Phosphorylation of Cytochrome c Threonine 28 Regulates Electron Transport Chain Activity in Kidney

Mahapatra, G., Varughese, A., Ji, Q., Lee, I., Liu, J., Vaishnav, A., Sinkler, C., Kapralov, A. A., Moraes, C. T., Sanderson, T. H., et al. (2017) · Journal of Biological Chemistry

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 61

Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool

Wang, X., Pickrell, A. M., Rossi, S. G., Pinto, M., Dillon, L. M., Hida, A., Rotundo, R. L., & Moraes, C. T. (2013) · Human Molecular Genetics

Muscle Physiology and DisordersMitochondrial Function and Pathology

Cited by 54

Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formation

Pinto, M., Pickrell, A. M., Fukui, H., & Moraes, C. T. (2013) · Neurobiology of Aging

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 47

Overexpression of twinkle-helicase protects cardiomyocytes from genotoxic stress caused by reactive oxygen species

Pohjoismäki, J. L. O., Williams, S. L., Boettger, T., Goffart, S., Kim, J., Suomalainen, A., Moraes, C. T., & Braun, T. (2013) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 45

Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage

Peralta, S., Torraco, A., Wenz, T., Garcia, S., Diaz, F., & Moraes, C. T. (2014) · Human Molecular Genetics

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 42

PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site

Ryan, C. B., Choi, J. S., Kang, B., Herr, S., Pereira, C., Moraes, C. T., Al-Ali, H., & Lee, J. K. (2024) · Neurobiology of Disease

Spinal Cord Injury ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 23