Newell, Evan W.

Dimensionality reduction for visualizing single-cell data using UMAP

Becht, E., McInnes, L., Healy, J., Dutertre, C.-A., Kwok, I. W. H., Ng, L. G., Ginhoux, F., & Newell, E. W. (2019) · Nature Biotechnology

Single-cell and spatial transcriptomicsFace and Expression Recognition

Cited by 5,358

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

Simoni, Y., Becht, E., Fehlings, M., Loh, C. Y., Koo, S.-L., Teng, K. W. W., Yeong, J. P. S., Nahar, R., Zhang, T., Kared, H., et al. (2018) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 1,370

Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes

Newell, E. W., Sigal, N., Bendall, S. C., Nolan, G. P., & Davis, M. M. (2012) · Immunity

T-cell and B-cell ImmunologyImmune Cell Function and Interaction

Cited by 555

Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans

Galletti, G., De Simone, G., Mazza, E. M. C., Puccio, S., Mezzanotte, C., Bi, T. M., Davydov, A. N., Metsger, M., Scamardella, E., Alvisi, G., et al. (2020) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 299

A subset of Kupffer cells regulates metabolism through the expression of CD36

Blériot, C., Barreby, E., Dunsmore, G., Ballaire, R., Chakarov, S., Ficht, X., De Simone, G., Andreata, F., Fumagalli, V., Guo, W., et al. (2021) · Immunity

Immune cells in cancerLiver physiology and pathology

Cited by 236

Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody

Ha, D., Tanaka, A., Kibayashi, T., Tanemura, A., Sugiyama, D., Wing, J. B., Lim, E. L., Teng, K. W. W., Adeegbe, D., Newell, E. W., et al. (2019) · Proceedings of the National Academy of Sciences

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 205

Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

Cheng, Y., Gunasegaran, B., Singh, H. D., Dutertre, C.-A., Loh, C. Y., Lim, J. Q., Crawford, J. C., Lee, H. K., Zhang, X., Lee, B., et al. (2021) · Immunity

Cancer Immunotherapy and BiomarkersHepatitis B Virus Studies

Cited by 142

Interrogating the repertoire: broadening the scope of peptide–MHC multimer analysis

Davis, M. M., Altman, J. D., & Newell, E. W. (2011) · Nature Reviews Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 124

A targeted multi-omic analysis approach measures protein expression and low abundance transcripts on the single cell level

Mair, F., Erickson, J. R., Voillet, V., Simoni, Y., Bi, T., Tyznik, A. J., Martin, J., Gottardo, R., Newell, E. W., & Prlic, M. (2019) · Cell Reports

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 111

High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy

Gubin, M. M., Esaulova, E., Ward, J. P., Malkova, O. N., Runci, D., Wong, P., Noguchi, T., Arthur, C. D., Meng, W., Alspach, E., et al. (2018) · Cell

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 98

CD103+ Dendritic Cells Control Th17 Cell Function in the Lung

Zelante, T., Wong, A. Y. W., Ping, T. J., Chen, J., Sumatoh, H. R., Viganò, E., Hong Bing, Y., Lee, B., Zolezzi, F., Fric, J., et al. (2015) · Cell Reports

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 90

Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease

Tan-Garcia, A., Wai, L.-E., Zheng, D., Ceccarello, E., Jo, J., Banu, N., Khakpoor, A., Chia, A., Tham, C. Y. L., Tan, A. T., et al. (2017) · Journal of Hepatology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 68

Categorical Analysis of Human T Cell Heterogeneity with One-Dimensional Soli-Expression by Nonlinear Stochastic Embedding

Cheng, Y., Wong, M. T., van der Maaten, L., & Newell, E. W. (2016) · The Journal of Immunology

Single-cell and spatial transcriptomicsCell Image Analysis Techniques

Cited by 67