Goreshnik, Inna

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

Cao, L., Goreshnik, I., Coventry, B., Case, J. B., Miller, L., Kozodoy, L., Chen, R. E., Carter, L., Walls, A. C., Park, Y.-J., et al. (2020) · Science

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 742

Design of protein-binding proteins from the target structure alone

Cao, L., Coventry, B., Goreshnik, I., Huang, B., Sheffler, W., Park, J. S., Jude, K. M., Marković, I., Kadam, R. U., Verschueren, K. H. G., et al. (2022) · Nature

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 577

Global analysis of protein folding using massively parallel design, synthesis, and testing

Rocklin, G. J., Chidyausiku, T. M., Goreshnik, I., Ford, A., Houliston, S., Lemak, A., Carter, L., Ravichandran, R., Mulligan, V. K., Chevalier, A., et al. (2017) · Science

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 501

Massively parallel de novo protein design for targeted therapeutics

Chevalier, A., Silva, D.-A., Rocklin, G. J., Hicks, D. R., Vergara, R., Murapa, P., Bernard, S. M., Zhang, L., Lam, K.-H., Yao, G., et al. (2017) · Nature

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 453

Improving de novo protein binder design with deep learning

Bennett, N. R., Coventry, B., Goreshnik, I., Huang, B., Allen, A., Vafeados, D., Peng, Y. P., Dauparas, J., Baek, M., Stewart, L., et al. (2023) · Nature Communications

Protein Structure and Dynamicsvaccines and immunoinformatics approaches

Cited by 402

Atomically accurate de novo design of antibodies with RFdiffusion

Bennett, N. R., Watson, J. L., Ragotte, R. J., Borst, A. J., See, D. L., Weidle, C., Biswas, R., Yu, Y., Shrock, E. L., Ault, R., et al. (2024) · Nature

Monoclonal and Polyclonal Antibodies ResearchProtein Structure and Dynamics

Cited by 324

Diffusing protein binders to intrinsically disordered proteins

Liu, C., Wu, K., Choi, H., Han, H. L., Zhang, X., Watson, J. L., Ahn, G., Zhang, J. Z., Shijo, S., Good, L. L., et al. (2025) · Nature

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 79

Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease

Case, J. B., Chen, R. E., Cao, L., Ying, B., Winkler, E. S., Johnson, M., Goreshnik, I., Pham, M. N., Shrihari, S., Kafai, N. M., et al. (2021) · Cell Host & Microbe

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 73

Computational design of sequence-specific DNA-binding proteins

Glasscock, C. J., Pecoraro, R. J., McHugh, R., Doyle, L. A., Chen, W., Boivin, O., Lonnquist, B., Na, E., Politanska, Y., Haddox, H. K., et al. (2025) · Nature Structural & Molecular Biology

Protein Structure and DynamicsCRISPR and Genetic Engineering

Cited by 58

Small-molecule binding and sensing with a designed protein family

Lee, G. R., Pellock, S. J., Norn, C., Tischer, D., Dauparas, J., Anischenko, I., Mercer, J. A. M., Kang, A., Bera, A., Nguyen, H., et al. (2023) · Nature Communications

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 41