Dwek, Raymond A.

Glycosylation and the Immune System

Rudd, P. M., Elliott, T., Cresswell, P., Wilson, I. A., & Dwek, R. A. (2001) · Science

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 1,588

Glycosylation changes of IgG associated with rheumatooid arthritis can activate complement via the mannose-binding protein

Malhotra, R., Wormald, M. R., Rudd, P. M., Fischer, P. B., Dwek, R. A., & Sim, R. B. (1995) · Nature Medicine

Glycosylation and Glycoproteins ResearchComplement system in diseases

Cited by 786

Emerging principles for the therapeutic exploitation of glycosylation

Dalziel, M., Crispin, M., Scanlan, C. N., Zitzmann, N., & Dwek, R. A. (2014) · Science

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 447

The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives

Pavlović, D., Neville, D. C. A., Argaud, O., Blumberg, B., Dwek, R. A., Fischer, W. B., & Zitzmann, N. (2003) · Proceedings of the National Academy of Sciences

Hepatitis C virus researchIon channel regulation and function

Cited by 390

Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase

Simpson, M. A., Cross, H., Proukakis, C., Priestman, D. A., Neville, D. C. A., Reinkensmeier, G., Wang, H., Wiznitzer, M., Gurtz, K., Verganelaki, A., et al. (2004) · Nature Genetics

Lysosomal Storage Disorders ResearchMetabolism and Genetic Disorders

Cited by 389

Antiviral effects of an iminosugar derivative on flavivirus infections

Wu, S.-F., Lee, C.-J., Liao, C.-L., Dwek, R. A., Zitzmann, N., & Lin, Y.-L. (2002) · Journal of Virology

Mosquito-borne diseases and controlEndoplasmic Reticulum Stress and Disease

Cited by 220

Variations in Oligosaccharide−Protein Interactions in Immunoglobulin G Determine the Site-Specific Glycosylation Profiles and Modulate the Dynamic Motion of the Fc Oligosaccharides

Wormald, M. R., Rudd, P. M., Harvey, D. J., Chang, S.-C., Scragg, I. G., & Dwek, R. A. (1997) · Biochemistry

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 191

Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytes.

Haurum, J. S., Arsequell, G., Lellouch, A. C., Wong, S. Y., Dwek, R. A., McMichael, A. J., & Elliott, T. (1994) · The Journal of experimental medicine

Glycosylation and Glycoproteins ResearchImmunotherapy and Immune Responses

Cited by 184

The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding

Fischer, P. B., Collin, M., Karlsson, G. B., James, W., Butters, T. D., Davis, S. J., Gordon, S., Dwek, R. A., & Platt, F. M. (1995) · Journal of Virology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 155

Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells

Pollock, S., Nichita, N. B., Böhmer, A., Radulescu, C., Dwek, R. A., & Zitzmann, N. (2010) · Proceedings of the National Academy of Sciences

Nanoparticle-Based Drug DeliveryHepatitis C virus research

Cited by 76

Cellular effects of deoxynojirimycin analogues: Inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides

MELLOR, H. R., NEVILLE, D. C. A., HARVEY, D. J., PLATT, F. M., DWEK, R. A., & BUTTERS, T. D. (2004) · Biochemical Journal

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 41

Human complement factor I glycosylation: Structural and functional characterisation of the N-linked oligosaccharides

Tsiftsoglou, S. A., Arnold, J. N., Roversi, P., Crispin, M. D., Radcliffe, C., Lea, S. M., Dwek, R. A., Rudd, P. M., & Sim, R. B. (2006) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Glycosylation and Glycoproteins ResearchComplement system in diseases

Cited by 29