Beijnen, Jos H.

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

Jonker, J. W., Buitelaar, M., Wagenaar, E., van der Valk, M. A., Scheffer, G. L., Scheper, R. J., Plösch, T., Kuipers, F., Elferink, R. P. J. O., Rosing, H., et al. (2002) · Proceedings of the National Academy of Sciences

Drug Transport and Resistance MechanismsPhotodynamic Therapy Research Studies

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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Keizer, R. J., Huitema, A. D. R., Schellens, J. H. M., & Beijnen, J. H. (2010) · Clinical Pharmacokinetics

Monoclonal and Polyclonal Antibodies ResearchBiosimilars and Bioanalytical Methods

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Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids

Roodhart, J. M. L., Daenen, L. G. M., Stigter, E. C. A., Prins, H.-J., Gerrits, J., Houthuijzen, J. M., Gerritsen, M. G., Schipper, H. S., Backer, M. J. G., van Amersfoort, M., et al. (2011) · Cancer Cell

Cancer Cells and MetastasisMesenchymal stem cell research

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Bevacizumab

Kazazi-Hyseni, F., Beijnen, J. H., & Schellens, J. H. M. (2010) · The Oncologist

Angiogenesis and VEGF in CancerColorectal Cancer Treatments and Studies

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Concise Review: Clinical Relevance of Drug–Drug and Herb–Drug Interactions Mediated by the ABC Transporter ABCB1 (MDR1, P-glycoprotein)

Marchetti, S., Mazzanti, R., Beijnen, J. H., & Schellens, J. H. M. (2007) · The Oncologist

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

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Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism

van Herwaarden, A. E., Wagenaar, E., van der Kruijssen, C. M. M., van Waterschoot, R. A. B., Smit, J. W., Song, J.-Y., van der Valk, M. A., van Tellingen, O., van der Hoorn, J. W. A., Rosing, H., et al. (2007) · Journal of Clinical Investigation

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

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Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses

Keizer, R. J., Jansen, R. S., Rosing, H., Thijssen, B., Beijnen, J. H., Schellens, J. H. M., & Huitema, A. D. R. (2015) · Pharmacology Research & Perspectives

Pharmaceutical studies and practicesStatistical Methods in Clinical Trials

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Fixed Dosing of Monoclonal Antibodies in Oncology

Hendrikx, J. J. M. A., Haanen, J. B. A. G., Voest, E. E., Schellens, J. H. M., Huitema, A. D. R., & Beijnen, J. H. (2017) · The Oncologist

Monoclonal and Polyclonal Antibodies ResearchPharmaceutical studies and practices

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Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2

de Gooijer, M. C., de Vries, N. A., Buckle, T., Buil, L. C. M., Beijnen, J. H., Boogerd, W., & van Tellingen, O. (2018) · Neoplasia

Drug Transport and Resistance MechanismsGlioma Diagnosis and Treatment

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Lapatinib for Advanced or Metastatic Breast Cancer

Opdam, F. L., Guchelaar, H.-J., Beijnen, J. H., & Schellens, J. H. M. (2012) · The Oncologist

HER2/EGFR in Cancer ResearchCancer Treatment and Pharmacology

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Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer

van Geel, R. M. J. M., van Brummelen, E. M. J., Eskens, F. A. L. M., Huijberts, S. C. F. A., de Vos, F. Y. F. L., Lolkema, M. P. J. K., Devriese, L. A., Opdam, F. L., Marchetti, S., Steeghs, N., et al. (2020) · British Journal of Cancer

Melanoma and MAPK PathwaysColorectal Cancer Treatments and Studies

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Phase I Study of Afatinib and Selumetinib in Patients with KRAS-Mutated Colorectal, Non-Small Cell Lung, and Pancreatic Cancer

Brummelen, E. M. J., Huijberts, S., Herpen, C., Desar, I., Opdam, F., Geel, R., Marchetti, S., Steeghs, N., Monkhorst, K., Thijssen, B., et al. (2021) · The Oncologist

Melanoma and MAPK PathwaysColorectal Cancer Treatments and Studies

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Dried Blood Spot Self-Sampling at Home for the Individualization of Tamoxifen Treatment: A Feasibility Study

Jager, N. G. L., Rosing, H., Linn, S. C., Schellens, J. H. M., & Beijnen, J. H. (2015) · Therapeutic Drug Monitoring

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Pharmacokinetics of Zidovudine and Acetaminophen in a Patient on Chronic Acetaminophen Therapy

Burger, D. M., Meenhorst, P. L., Koks, C. H. W., & Beijnen, J. H. (1994) · Annals of Pharmacotherapy

HIV/AIDS drug development and treatmentPharmacogenetics and Drug Metabolism

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Clinical trial simulations in paediatric oncology: A feasibility study from the Innovative Therapies for Children with Cancer Consortium

Janssen, J. M., Zwaan, C. M., Schellens, J. H. M., Beijnen, J. H., & Huitema, A. D. R. (2017) · European Journal of Cancer

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Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models

Damoiseaux, D., Beijnen, J. H., Huitema, A. D. R., & Dorlo, T. P. C. (2024) · Drug Metabolism and Disposition

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