Issa, Jean-Pierre J.

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

Issa, J.-P. J., Ottaviano, Y. L., Celano, P., Hamilton, S. R., Davidson, N. E., & Baylin, S. B. (1994) · Nature Genetics

Epigenetics and DNA MethylationGenetic factors in colorectal cancer

Cited by 1,191

Dnmt3a is essential for hematopoietic stem cell differentiation

Challen, G. A., Sun, D., Jeong, M., Luo, M., Jelinek, J., Berg, J. S., Bock, C., Vasanthakumar, A., Gu, H., Xi, Y., et al. (2012) · Nature Genetics

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

Cited by 1,122

DNA methylation aging clocks: challenges and recommendations

Bell, C. G., Lowe, R., Adams, P. D., Baccarelli, A. A., Beck, S., Bell, J. T., Christensen, B. C., Gladyshev, V. N., Heijmans, B. T., Horvath, S., et al. (2019) · Genome Biology

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 1,025

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF -Mutated Colorectal Cancer

Kopetz, S., Desai, J., Chan, E., Hecht, J. R., O'Dwyer, P. J., Maru, D., Morris, V., Janku, F., Dasari, A., Chung, W., et al. (2015) · Journal of Clinical Oncology

Colorectal Cancer Treatments and StudiesLung Cancer Treatments and Mutations

Cited by 697

Widespread and tissue specific age-related DNA methylation changes in mice

Maegawa, S., Hinkal, G., Kim, H. S., Shen, L., Zhang, L., Zhang, J., Zhang, N., Liang, S., Donehower, L. A., & Issa, J.-P. J. (2010) · Genome Research

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 553

Fusobacterium in Colonic Flora and Molecular Features of Colorectal Carcinoma

Tahara, T., Yamamoto, E., Suzuki, H., Maruyama, R., Chung, W., Garriga, J., Jelinek, J., Yamano, H.-O., Sugai, T., An, B., et al. (2014) · Cancer Research

Gut microbiota and healthGenetic factors in colorectal cancer

Cited by 465

p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

Wales, M. M., Biel, M. A., Deiry, W. E., Nelkin, B. D., Issa, J.-P., Cavenee, W. K., Kuerbitz, S. J., & Baylin, S. B. (1995) · Nature Medicine

Cancer-related Molecular PathwaysEpigenetics and DNA Methylation

Cited by 421

Aging and epigenetic drift: a vicious cycle

Issa, J.-P. (2014) · Journal of Clinical Investigation

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 419

Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia

Kuang, S.-Q., Tong, W.-G., Yang, H., Lin, W., Lee, M. K., Fang, Z. H., Wei, Y., Jelinek, J., Issa, J.-P., & Garcia-Manero, G. (2008) · Leukemia

Epigenetics and DNA MethylationAcute Lymphoblastic Leukemia research

Cited by 165