Sanglard, Dominique

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

Fisher, M. C., Hawkins, N. J., Sanglard, D., & Gurr, S. J. (2018) · Science

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 1,555

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

Sanglard, D., Kuchler, K., Ischer, F., Pagani, J. L., Monod, M., & Bille, J. (1995) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 815

Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

Sanglard, D., & Odds, F. C. (2002) · The Lancet Infectious Diseases

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 784

Mechanisms of Antifungal Drug Resistance

Cowen, L. E., Sanglard, D., Howard, S. J., Rogers, P. D., & Perlin, D. S. (2015) · Cold Spring Harbor Perspectives in Medicine

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 647

Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene

Sanglard, D., Ischer, F., Monod, M., & Bille, J. (1997) · Microbiology

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 587

Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in Candida albicans Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients

Perea, S., López-Ribot, J. L., Kirkpatrick, W. R., McAtee, R. K., Santillán, R. A., Martı́nez, M., Calabrese, D., Sanglard, D., & Patterson, T. F. (2001) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 470

TAC1 , Transcriptional Activator of CDR Genes, Is a New Transcription Factor Involved in the Regulation of Candida albicans ABC Transporters CDR1 and CDR2

Coste, A. T., Karababa, M., Ischer, F., Bille, J., & Sanglard, D. (2004) · Eukaryotic Cell

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 407

Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents

Sanglard, D., Ischer, F., Parkinson, T., Falconer, D., & Bille, J. (2003) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 398

A Mutation in Tac1p, a Transcription Factor Regulating CDR1 and CDR2 , Is Coupled With Loss of Heterozygosity at Chromosome 5 to Mediate Antifungal Resistance in Candida albicans

Coste, A., Turner, V., Ischer, F., Morschhäuser, J., Forche, A., Selmecki, A., Berman, J., Bille, J., & Sanglard, D. (2006) · Genetics

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 385

Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence

Sanglard, D., Ischer, F., Marchetti, O., Entenza, J., & Bille, J. (2003) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 350

A Human-Curated Annotation of the Candida albicans Genome

Braun, B. R., van het Hoog, M., d'Enfert, C., Martchenko, M., Dungan, J., Kuo, A., Inglis, D. O., Uhl, M. A., Hogues, H., Berriman, M., et al. (2005) · PLoS Genetics

Fungal and yeast genetics researchGenomics and Phylogenetic Studies

Cited by 342

The ATP Binding Cassette Transporter Gene CgCDR1 from Candida glabrata Is Involved in the Resistance of Clinical Isolates to Azole Antifungal Agents

Sanglard, D., Ischer, F., Calabrese, D., Majcherczyk, P. A., & Bille, J. (1999) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 337

Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates

Coste, A., Selmecki, A., Forche, A., Diogo, D., Bougnoux, M.-E., d'Enfert, C., Berman, J., & Sanglard, D. (2007) · Eukaryotic Cell

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 305

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

Ferrari, S., Ischer, F., Calabrese, D., Posteraro, B., Sanguinetti, M., Fadda, G., Rohde, B., Bauser, C., Bader, O., & Sanglard, D. (2009) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 295

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

Sanglard, D., Coste, A., & Ferrari, S. (2009) · FEMS Yeast Research

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 285

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.

Healey, K. R., Zhao, Y., Perez, W. B., Lockhart, S. R., Sobel, J. D., Farmakiotis, D., Kontoyiannis, D. P., Sanglard, D., Taj-Aldeen, S. J., Alexander, B. D., et al. (2016) · Nature Communications

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 276

Potent Synergism of the Combination of Fluconazole and Cyclosporine in Candida albicans

Marchetti, O., Moreillon, P., Glauser, M. P., Bille, J., & Sanglard, D. (2000) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 252

Role of ATP-Binding-Cassette Transporter Genes in High-Frequency Acquisition of Resistance to Azole Antifungals in Candida glabrata

Sanglard, D., Ischer, F., & Bille, J. (2001) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 247

CRZ1 , a target of the calcineurin pathway in Candida albicans

Karababa, M., Valentino, E., Pardini, G., Coste, A. T., Bille, J., & Sanglard, D. (2006) · Molecular Microbiology

Fungal and yeast genetics researchSignaling Pathways in Disease

Cited by 231

Distinct Patterns of Gene Expression Associated with Development of Fluconazole Resistance in Serial Candida albicans Isolates from Human Immunodeficiency Virus-Infected Patients with Oropharyngeal Candidiasis

Lopez-Ribot, J. L., McAtee, R. K., Lee, L. N., Kirkpatrick, W. R., White, T. C., Sanglard, D., & Patterson, T. F. (1998) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 210

Evolution of Drug Resistance in Experimental Populations of Candida albicans

Cowen, L. E., Sanglard, D., Calabrese, D., Sirjusingh, C., Anderson, J. B., & Kohn, L. M. (2000) · Journal of Bacteriology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 207

Increased expression of a novel Aspergillus fumigatus ABC transporter gene, atrF, in the presence of itraconazole in an itraconazole resistant clinical isolate

Slaven, J. W., Anderson, M. J., Sanglard, D., Dixon, G. K., Bille, J., Roberts, I. S., & Denning, D. W. (2002) · Fungal Genetics and Biology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 202

Identification and Expression of Multidrug Transporters Responsible for Fluconazole Resistance in Candida dubliniensis

Moran, G. P., Sanglard, D., Donnelly, S. M., Shanley, D. B., Sullivan, D. J., & Coleman, D. C. (1998) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 197

Rhodamine 6G efflux for the detection of CDR1-overexpressing azole-resistant Candidaalbicans strains

Maesaki, S., Marichal, P., Bossche, H. V., Sanglard, D., & Kohno, S. (1999) · Journal of Antimicrobial Chemotherapy

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 162