Sassetti, Christopher M.

Genes required for mycobacterial growth defined by high density mutagenesis

Sassetti, C. M., Boyd, D. H., & Rubin, E. J. (2003) · Molecular Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 2,544

Mycobacterial persistence requires the utilization of host cholesterol

Pandey, A. K., & Sassetti, C. M. (2008) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 1,064

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

Griffin, J. E., Gawronski, J. D., DeJesus, M. A., Ioerger, T. R., Akerley, B. J., & Sassetti, C. M. (2011) · PLoS Pathogens

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 1,048

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β

Mishra, B. B., Rathinam, V. A. K., Martens, G. W., Martinot, A. J., Kornfeld, H., Fitzgerald, K. A., & Sassetti, C. M. (2013) · Nature Immunology

Inflammasome and immune disordersTuberculosis Research and Epidemiology

Cited by 571

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

Rock, J. M., Hopkins, F. F., Chavez, A., Diallo, M., Chase, M. R., Gerrick, E. R., Pritchard, J. R., Church, G. M., Rubin, E. J., Sassetti, C. M., et al. (2017) · Nature Microbiology

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 538

Mutually dependent secretion of proteins required for mycobacterial virulence.

Fortune, S. M., Jaeger, A., Sarracino, D. A., Chase, M. R., Sassetti, C. M., Sherman, D. R., Bloom, B. R., & Rubin, E. J. (2005) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 396

Metabolic Regulation of Mycobacterial Growth and Antibiotic Sensitivity

Baek, S.-H., Li, A. H., & Sassetti, C. M. (2011) · PLoS Biology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 324

RNA secondary structure and binding sites for gag gene products in the 5’ packaging signal of human immunodeficiency virus type 1

Clever, J., Sassetti, C., & Parslow, T. G. (1995) · Journal of Virology

HIV Research and TreatmentRNA and protein synthesis mechanisms

Cited by 307

Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA

Köster, S., Upadhyay, S., Chandra, P., Papavinasasundaram, K., Yang, G., Hassan, A., Grigsby, S. J., Mittal, E., Park, H. S., Jones, V., et al. (2017) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 208

Subpolar addition of new cell wall is directed by DivIVA in mycobacteria

Meniche, X., Otten, R., Siegrist, M. S., Baer, C. E., Murphy, K. C., Bertozzi, C. R., & Sassetti, C. M. (2014) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 175

A Novel P1B-type Mn2+-transporting ATPase Is Required for Secreted Protein Metallation in Mycobacteria

Padilla-Benavides, T., Long, J. E., Raimunda, D., Sassetti, C. M., & Argüello, J. M. (2013) · Journal of Biological Chemistry

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 91

Spatially distinct and metabolically active membrane domain in mycobacteria

Hayashi, J. M., Luo, C.-Y., Mayfield, J. A., Hsu, T., Fukuda, T., Walfield, A. L., Giffen, S. R., Leszyk, J. D., Baer, C. E., Bennion, O. T., et al. (2016) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 83

A Parallel Adder Coordinates Mycobacterial Cell-Cycle Progression and Cell-Size Homeostasis in the Context of Asymmetric Growth and Organization

Logsdon, M. M., Ho, P.-Y., Papavinasasundaram, K., Richardson, K., Cokol, M., Sassetti, C. M., Amir, A., & Aldridge, B. B. (2017) · Current Biology

Bacterial Genetics and BiotechnologyGene Regulatory Network Analysis

Cited by 69