Kolls, Jay K.

Targeting IL-17 and TH17 cells in chronic inflammation

Miossec, P., & Kolls, J. K. (2012) · Nature Reviews Drug Discovery

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 1,414

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

Phinney, D. G., Di Giuseppe, M., Njah, J., Sala, E., Shiva, S., St Croix, C. M., Stolz, D. B., Watkins, S. C., Di, Y. P., Leikauf, G. D., et al. (2015) · Nature Communications

Extracellular vesicles in diseaseMesenchymal stem cell research

Cited by 1,007

Ectopic colonization of oral bacteria in the intestine drives T H 1 cell induction and inflammation

Atarashi, K., Suda, W., Luo, C., Kawaguchi, T., Motoo, I., Narushima, S., Kiguchi, Y., Yasuma, K., Watanabe, E., Tanoue, T., et al. (2017) · Science

Gut microbiota and healthInflammatory Bowel Disease

Cited by 957

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

O'Connor Jr, W., Kamanaka, M., Booth, C. J., Town, T., Nakae, S., Iwakura, Y., Kolls, J. K., & Flavell, R. A. (2009) · Nature Immunology

Psoriasis: Treatment and PathogenesisInflammatory Bowel Disease

Cited by 756

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

Cho, J. S., Pietras, E. M., Garcia, N. C., Ramos, R. I., Farzam, D. M., Monroe, H. R., Magorien, J. E., Blauvelt, A., Kolls, J. K., Cheung, A. L., et al. (2010) · Journal of Clinical Investigation

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 658

Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity

Overacre-Delgoffe, A. E., Chikina, M., Dadey, R. E., Yano, H., Brunazzi, E. A., Shayan, G., Horne, W., Moskovitz, J. M., Kolls, J. K., Sander, C., et al. (2017) · Cell

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 627

The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice

Deshmukh, H. S., Liu, Y., Menkiti, O. R., Mei, J., Dai, N., O'Leary, C. E., Oliver, P. M., Kolls, J. K., Weiser, J. N., & Worthen, G. S. (2014) · Nature Medicine

Gut microbiota and healthNeonatal and Maternal Infections

Cited by 579

Proinflammatory T helper type 17 cells are effective B-cell helpers

Mitsdoerffer, M., Lee, Y., Jäger, A., Kim, H.-J., Korn, T., Kolls, J. K., Cantor, H., Bettelli, E., & Kuchroo, V. K. (2010) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 534

The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus

Steele, C., Rapaka, R. R., Metz, A., Pop, S. M., Williams, D. L., Gordon, S., Kolls, J. K., & Brown, G. D. (2005) · PLoS Pathogens

Antifungal resistance and susceptibilityImmune Response and Inflammation

Cited by 509

The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin

Weaver, C. T., Elson, C. O., Fouser, L. A., & Kolls, J. K. (2013) · Annual Review of Pathology Mechanisms of Disease

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 462

The development of inducible bronchus-associated lymphoid tissue depends on IL-17

Rangel-Moreno, J., Carragher, D. M., de la Luz Garcia-Hernandez, M., Hwang, J. Y., Kusser, K., Hartson, L., Kolls, J. K., Khader, S. A., & Randall, T. D. (2011) · Nature Immunology

T-cell and B-cell ImmunologyIL-33, ST2, and ILC Pathways

Cited by 441

Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia

McAllister, F., Bailey, J. M., Alsina, J., Nirschl, C. J., Sharma, R., Fan, H., Rattigan, Y., Roeser, J. C., Lankapalli, R. H., Zhang, H., et al. (2014) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 405

Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice.

Kudva, A., Scheller, E. V., Robinson, K. M., Crowe, C. R., Choi, S. M., Slight, S. R., Khader, S. A., Dubin, P. J., Enelow, R. I., Kolls, J. K., et al. (2011) · The Journal of Immunology

Influenza Virus Research Studiesinterferon and immune responses

Cited by 346

Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation

Kumar, P., Monin, L., Castillo, P., Elsegeiny, W., Horne, W., Eddens, T., Vikram, A., Good, M., Schoenborn, A. A., Bibby, K., et al. (2016) · Immunity

Psoriasis: Treatment and PathogenesisGut microbiota and health

Cited by 326

Contributions of the intestinal microbiome in lung immunity

McAleer, J. P., & Kolls, J. K. (2018) · European Journal of Immunology

Gut microbiota and healthAsthma and respiratory diseases

Cited by 243

IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis

Conti, H. R., Bruno, V. M., Childs, E. E., Daugherty, S., Hunter, J. P., Mengesha, B. G., Saevig, D. L., Hendricks, M. R., Coleman, B. M., Brane, L., et al. (2016) · Cell Host & Microbe

Antifungal resistance and susceptibilityAntimicrobial Peptides and Activities

Cited by 177

MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation

Garg, A. V., Amatya, N., Chen, K., Cruz, J. A., Grover, P., Whibley, N., Conti, H. R., Hernandez Mir, G., Sirakova, T., Childs, E. C., et al. (2015) · Immunity

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 145

The immunology of influenza virus-associated bacterial pneumonia.

Robinson, K. M., Kolls, J. K., & Alcorn, J. F. (2015) · Current Opinion in Immunology

Influenza Virus Research StudiesImmune Response and Inflammation

Cited by 132

Influenza A Virus Exacerbates Staphylococcus aureus Pneumonia in Mice by Attenuating Antimicrobial Peptide Production

Robinson, K. M., McHugh, K. J., Mandalapu, S., Clay, M. E., Lee, B., Scheller, E. V., Enelow, R. I., Chan, Y. R., Kolls, J. K., & Alcorn, J. F. (2014) · The Journal of Infectious Diseases

Influenza Virus Research StudiesAntimicrobial Peptides and Activities

Cited by 131

TNF-α from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

Fei, M., Bhatia, S., Oriss, T. B., Yarlagadda, M., Khare, A., Akira, S., Saijo, S., Iwakura, Y., Fallert Junecko, B. A., Reinhart, T. A., et al. (2011) · Proceedings of the National Academy of Sciences

Asthma and respiratory diseasesAntifungal resistance and susceptibility

Cited by 127

Influenza A Exacerbates Staphylococcus aureus Pneumonia by Attenuating IL-1β Production in Mice

Robinson, K. M., Choi, S. M., McHugh, K. J., Mandalapu, S., Enelow, R. I., Kolls, J. K., & Alcorn, J. F. (2013) · The Journal of Immunology

Inflammasome and immune disordersInfluenza Virus Research Studies

Cited by 126

Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis

Aggor, F. E. Y., Break, T. J., Trevejo-Nuñez, G., Whibley, N., Coleman, B. M., Bailey, R. D., Kaplan, D. H., Naglik, J. R., Shan, W., Shetty, A. C., et al. (2020) · Science Immunology

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 119

Stress and bronchodilator response in children with asthma

Brehm, J. M., Ramratnam, S. K., Tse, S. M., Croteau-Chonka, D. C., Pino-Yanes, M., Rosas-Salazar, C., Litonjua, A. A., Raby, B. A., Boutaoui, N., Han, Y.-Y., et al. (2015) · American Journal of Respiratory and Critical Care Medicine

Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 106

Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes

Chan, Y. R., Chen, K., Duncan, S. R., Lathrop, K. L., Latoche, J. D., Logar, A. J., Pociask, D. A., Wahlberg, B. J., Ray, P., Ray, A., et al. (2013) · Journal of Allergy and Clinical Immunology

Cystic Fibrosis Research AdvancesPsoriasis: Treatment and Pathogenesis

Cited by 73