Sahel, José-Alain

Optogenetic Light Sensors in Human Retinal Organoids

Garita-Hernandez, M., Guibbal, L., Toualbi, L., Routet, F., Chaffiol, A., Winckler, C., Harinquet, M., Robert, C., Fouquet, S., Bellow, S., et al. (2018) · Frontiers in Neuroscience

Photoreceptor and optogenetics researchRetinal Development and Disorders

Cited by 65

Intravitreal Gene Therapy vs. Natural History in Patients With Leber Hereditary Optic Neuropathy Carrying the m.11778G>A ND4 Mutation: Systematic Review and Indirect Comparison

Newman, N. J., Yu-Wai-Man, P., Carelli, V., Biousse, V., Moster, M. L., Vignal-Clermont, C., Sergott, R. C., Klopstock, T., Sadun, A. A., Girmens, J.-F., et al. (2021) · Frontiers in Neurology

Virus-based gene therapy researchGlaucoma and retinal disorders

Cited by 64

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

Strunz, T., Lauwen, S., Kiel, C., International AMD Genomics Consortium (IAMDGC), Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., et al. (2020) · Scientific Reports

Genetic Associations and EpidemiologyRetinal Diseases and Treatments

Cited by 60

Phase 1/2 AAV5-hRKp.RPGR (botaretigene sparoparvovec) gene therapy: safety and efficacy in RPGR-associated X-linked retinitis pigmentosa

MICHAELIDES, M., BESIRLI, C. G., YANG, Y., DE GUIMARAES, T. A. C., WONG, S. C., HUCKFELDT, R. M., COMANDER, J. I., SAHEL, J.-A., SHAH, S. M., TEE, J. J. L., et al. (2024) · American Journal of Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 55

Safety of intravitreal gene therapy for treatment of subjects with Leber hereditary optic neuropathy due to mutations in the mitochondrial ND4 gene: The REVEAL study

Vignal-Clermont, C., Girmens, J.-F., Audo, I., Said, S. M., Errera, M.-H., Plaine, L., O’Shaughnessy, D., Taiel, M., & Sahel, J.-A. (2021) · BioDrugs

Glaucoma and retinal disordersRetinal Development and Disorders

Cited by 51

Gene therapy for mitochondrial diseases: Leber hereditary optic neuropathy as the first candidate for a clinical trial.

Cwerman-Thibault, H., Augustin, S., Ellouze, S., Sahel, J.-A., & Corral-Debrinski, M. (2014) · Comptes Rendus. Biologies

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 49

AAV‐mediated gene delivery in Dp71‐null mouse model with compromised barriers

Vacca, O., Darche, M., Schaffer, D. V., Flannery, J. G., Sahel, J., Rendon, A., & Dalkara, D. (2014) · Glia

Retinal Development and DisordersVirus-based gene therapy research

Cited by 48

Six-month safety and efficacy of the intelligent retinal implant system II device in retinitis pigmentosa

Muqit, M. M. K., Velikay-Parel, M., Weber, M., Dupeyron, G., Audemard, D., Corcostegui, B., Sahel, J., & Le Mer, Y. (2019) · Ophthalmology

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 46

Importance of eye position on spatial localization in blind subjects wearing an Argus II retinal prosthesis

Sabbah, N., Authie, C. N., Sanda, N., Mohand-Said, S., Sahel, J.-A., & Safran, A. B. (2014) · Investigative Ophthalmology & Visual Science

Neuroscience and Neural EngineeringTactile and Sensory Interactions

Cited by 45

Biodistribution of intravitreal lenadogene nolparvovec gene therapy in nonhuman primates

Calkins, D. J., Yu-Wai-Man, P., Newman, N. J., Taiel, M., Singh, P., Chalmey, C., Rogue, A., Carelli, V., Ancian, P., & Sahel, J. A. (2021) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 37

Safety of lenadogene nolparvovec gene therapy over 5 Years in 189 patients with leber hereditary optic neuropathy

VIGNAL-CLERMONT, C., YU-WAI-MAN, P., NEWMAN, N. J., CARELLI, V., MOSTER, M. L., BIOUSSE, V., SUBRAMANIAN, P. S., WANG, A.-G., DONAHUE, S. P., LEROY, B. P., et al. (2023) · American Journal of Ophthalmology

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 25

Association between Visual Acuity and Medical and Non-Medical Costs in Patients with Wet Age-Related Macular Degeneration in France, Germany and Italy

Bandello, F., Augustin, A., Sahel, J.-A., Benhaddi, H., Negrini, C., Hieke, K., & Berdeaux (2008) · Drugs & Aging

Retinal Diseases and TreatmentsHealth Systems, Economic Evaluations, Quality of Life

Cited by 19

Selective neural coding of object, feature, and geometry spatial cues in humans

Ramanoël, S., Durteste, M., Bizeul, A., Ozier‐Lafontaine, A., Bécu, M., Sahel, J., Habas, C., & Arleo, A. (2022) · Human Brain Mapping

Spatial Cognition and NavigationMemory and Neural Mechanisms

Cited by 15

268. Optogenetic Engineering of Retinal Ganglion Cells with AAV2.7m8-ChrimsonR-tdTomato (GS030-DP) Is Well Tolerated and Induces Functional Responses to Light in Non-Human Primates

Douar, A. M., Bouquet, C., Pruneau, D., Chavas, J., Dalkara, D., Duebel, J., Benosman, R., Chenegros, G., Picaud, S., Sahel, J., et al. (2016) · Molecular Therapy

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 11

Cross-sectional analysis of baseline visual parameters in subjects recruited into the RESCUE and REVERSE ND4-LHON gene therapy studies

Moster, M. L., Sergott, R. C., Newman, N. J., Yu-Wai-Man, P., Carelli, V., Bryan, M. S., Smits, G., Biousse, V., Vignal-Clermont, C., Klopstock, T., et al. (2021) · Journal of Neuro-Ophthalmology

Glaucoma and retinal disordersRetinal Development and Disorders

Cited by 7