Derhovanessian, Evelyna

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Sahin, U., Derhovanessian, E., Miller, M., Kloke, B.-P., Simon, P., Löwer, M., Bukur, V., Tadmor, A. D., Luxemburger, U., Schrörs, B., et al. (2017) · Nature

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 2,488

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

Sahin, U., Muik, A., Derhovanessian, E., Vogler, I., Kranz, L. M., Vormehr, M., Baum, A., Pascal, K., Quandt, J., Maurus, D., et al. (2020) · Nature

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 1,977

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Kranz, L. M., Diken, M., Haas, H., Kreiter, S., Loquai, C., Reuter, K. C., Meng, M., Fritz, D., Vascotto, F., Hefesha, H., et al. (2016) · Nature

Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery

Cited by 1,819

Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer

Rojas, L. A., Sethna, Z., Soares, K. C., Olcese, C., Pang, N., Patterson, E., Lihm, J., Ceglia, N., Guasp, P., Chu, A., et al. (2023) · Nature

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 1,432

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

Sahin, U., Oehm, P., Derhovanessian, E., Jabulowsky, R. A., Vormehr, M., Gold, M., Maurus, D., Schwarck-Kokarakis, D., Kuhn, A. N., Omokoko, T., et al. (2020) · Nature

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 1,052

Actively personalized vaccination trial for newly diagnosed glioblastoma

Hilf, N., Kuttruff-Coqui, S., Frenzel, K., Bukur, V., Stevanović, S., Gouttefangeas, C., Platten, M., Tabatabai, G., Dutoit, V., van der Burg, S. H., et al. (2019) · Nature

Glioma Diagnosis and TreatmentImmunotherapy and Immune Responses

Cited by 938

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Sahin, U., Muik, A., Vogler, I., Derhovanessian, E., Kranz, L. M., Vormehr, M., Quandt, J., Bidmon, N., Ulges, A., Baum, A., et al. (2021) · Nature

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 919

BNT162b2 induces SARS-CoV-2-neutralising antibodies and T cells in humans

Sahin, U., Muik, A., Vogler, I., Derhovanessian, E., Kranz, L. M., Vormehr, M., Quandt, J., Bidmon, N., Ulges, A., Baum, A., et al. (2020) · Nature

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 914

Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients

Weide, B., Pascolo, S., Scheel, B., Derhovanessian, E., Pflugfelder, A., Eigentler, T. K., Pawelec, G., Hoerr, I., Rammensee, H.-G., & Garbe, C. (2009) · Journal of Immunotherapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 378

Biomarkers of human immunosenescence: impact of cytomegalovirus infection

Derhovanessian, E., Larbi, A., & Pawelec, G. (2009) · Current Opinion in Immunology

Cytomegalovirus and herpesvirus researchTelomeres, Telomerase, and Senescence

Cited by 220

Role of CMV in immune senescence.

Pawelec, G., & Derhovanessian, E. (2011) · Virus Research

Cytomegalovirus and herpesvirus researchTelomeres, Telomerase, and Senescence

Cited by 201

Immunity, ageing and cancer

Derhovanessian, E., Solana, R., Larbi, A., & Pawelec, G. (2008) · Immunity & Ageing

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 169

New advances in CMV and immunosenescence

Sansoni, P., Vescovini, R., Fagnoni, F. F., Akbar, A., Arens, R., Chiu, Y.-L., Čičin-Šain, L., Dechanet-Merville, J., Derhovanessian, E., Ferrando-Martinez, S., et al. (2014) · Experimental Gerontology

Cytomegalovirus and herpesvirus researchImmune responses and vaccinations

Cited by 150

Impact of age, sex and CMV-infection on peripheral T cell phenotypes: results from the Berlin BASE-II Study

Di Benedetto, S., Derhovanessian, E., Steinhagen-Thiessen, E., Goldeck, D., Müller, L., & Pawelec, G. (2015) · Biogerontology

T-cell and B-cell ImmunologyCytomegalovirus and herpesvirus research

Cited by 131

Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination

Derhovanessian, E., Theeten, H., Hähnel, K., Van Damme, P., Cools, N., & Pawelec, G. (2013) · Vaccine

Influenza Virus Research StudiesImmune responses and vaccinations

Cited by 121

Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people

Derhovanessian, E., Maier, A. B., Hähnel, K., Zelba, H., de Craen, A. J. M., Roelofs, H., Slagboom, E. P., Westendorp, R. G. J., & Pawelec, G. (2013) · AGE

T-cell and B-cell ImmunologyCytomegalovirus and herpesvirus research

Cited by 102

Latent infection with cytomegalovirus is associated with poor memory CD4 responses to influenza A core proteins in the elderly

Derhovanessian, E., Maier, A. B., Hähnel, K., McElhaney, J. E., Slagboom, E. P., & Pawelec, G. (2014) · The Journal of Immunology

Influenza Virus Research StudiesCytomegalovirus and herpesvirus research

Cited by 93

Age-associated alterations in γδ T-cells are present predominantly in individuals infected with Cytomegalovirus

Wistuba-Hamprecht, K., Frasca, D., Blomberg, B., Pawelec, G., & Derhovanessian, E. (2013) · Immunity & Ageing

Cytomegalovirus and herpesvirus researchT-cell and B-cell Immunology

Cited by 52

Vaccination in the elderly

Derhovanessian, E., & Pawelec, G. (2012) · Microbial Biotechnology

Influenza Virus Research StudiesImmune responses and vaccinations

Cited by 51

Phase I trial of adjuvant autogene cevumeran, an individualized mRNA neoantigen vaccine, for pancreatic ductal adenocarcinoma

Balachandran, V. P., Rojas, L. A., Sethna, Z., Soares, K., Derhovanessian, E., Mueller, F., Yadav, M., Basturk, O., Gonen, M., Wei, A. C.-C., et al. (2022) · Journal of Clinical Oncology

Pancreatic and Hepatic Oncology ResearchImmunotherapy and Immune Responses

Cited by 33

Publisher Correction: COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

Sahin, U., Muik, A., Derhovanessian, E., Vogler, I., Kranz, L. M., Vormehr, M., Baum, A., Pascal, K., Quandt, J., Maurus, D., et al. (2021) · Nature

SARS-CoV-2 and COVID-19 ResearchImmunotherapy and Immune Responses

Cited by 31