Cookson, Mark R.

Hexokinase activity is required for recruitment of parkin to depolarized mitochondria

McCoy, M. K., Kaganovich, A., Rudenko, I. N., Ding, J., & Cookson, M. R. (2014) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 97

Association of a common genetic variant with Parkinson’s disease is mediated by microglia

Langston, R. G., Beilina, A., Reed, X., Kaganovich, A., Singleton, A. B., Blauwendraat, C., Gibbs, J. R., & Cookson, M. R. (2022) · Science Translational Medicine

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 93

The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease

Bandres‐Ciga, S., Saez‐Atienzar, S., Bonet‐Ponce, L., Billingsley, K., Vitale, D., Blauwendraat, C., Gibbs, J. R., Pihlstrøm, L., Gan‐Or, Z., The International Parkinson's Disease Genomics Consortium (IPDGC), et al. (2019) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsGenetic Associations and Epidemiology

Cited by 90

The Metalloprotease Inhibitor TIMP-3 Regulates Amyloid Precursor Protein and Apolipoprotein E Receptor Proteolysis

Hoe, H.-S., Cooper, M. J., Burns, M. P., Lewis, P. A., van der Brug, M., Chakraborty, G., Cartagena, C. M., Pak, D. T. S., Cookson, M. R., & Rebeck, G. W. (2007) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 90

Pathways to Parkinsonism Redux: convergent pathobiological mechanisms in genetics of Parkinson's disease

Kumaran, R., & Cookson, M. R. (2015) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 86

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

Kim, C., Beilina, A., Smith, N., Li, Y., Kim, M., Kumaran, R., Kaganovich, A., Mamais, A., Adame, A., Iba, M., et al. (2020) · Science Translational Medicine

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 79

Expression of PINK1 mRNA in human and rodent brain and in Parkinson's disease

Blackinton, J. G., Anvret, A., Beilina, A., Olson, L., Cookson, M. R., & Galter, D. (2007) · Brain Research

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 59

APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

Area-Gomez, E., Larrea, D., Pera, M., Agrawal, R. R., Guilfoyle, D. N., Pirhaji, L., Shannon, K., Arain, H. A., Ashok, A., Chen, Q., et al. (2020) · Scientific Reports

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 55

Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4

Stephenson, R. A., Sepulveda, J., Johnson, K. R., Lita, A., Gopalakrishnan, J., Acri, D. J., Beilina, A., Cheng, L., Yang, L. G., Root, J. T., et al. (2025) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsLipid metabolism and biosynthesis

Cited by 55

The impact of fraudulent and irreproducible data to the translational research crisis – solutions and implementation

Schulz, J. B., Cookson, M. R., & Hausmann, L. (2016) · Journal of Neurochemistry

Animal testing and alternativesAcademic Publishing and Open Access

Cited by 52

Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci

Holton, P., Ryten, M., Nalls, M., Trabzuni, D., Weale, M. E., Hernandez, D., Crehan, H., Gibbs, J. R., Mayeux, R., Haines, J. L., et al. (2013) · Annals of Human Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 48

Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies

Erskine, D., Ding, J., Thomas, A. J., Kaganovich, A., Khundakar, A. A., Hanson, P. S., Taylor, J., McKeith, I. G., Attems, J., Cookson, M. R., et al. (2018) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 40

Structure and regulation of full-length human leucine-rich repeat kinase 1

Metcalfe, R. D., Martinez Fiesco, J. A., Bonet-Ponce, L., Kluss, J. H., Cookson, M. R., & Zhang, P. (2023) · Nature Communications

Protein Kinase Regulation and GTPase SignalingParkinson's Disease Mechanisms and Treatments

Cited by 8

APOE genotypes differentially remodel the astrocytic lipid droplet proteome to shape lipid droplet dynamics

Cuní-López, C., Root, J. T., Hao, Y., Blomberg, N., Koppes-den Hertog, S. J., Sacks, D., Trujillo, A. E., Ghirlando, R., Kowal, I., Epstein, J., et al. (2026) · Nature Communications

Lipid metabolism and biosynthesisAlzheimer's disease research and treatments

Cited by 0

Semi-automated annotation refinement accelerates cell type identification in brain spatial and single-cell studies

Acri, D. J., Mustaklem, R., Horan-Portelance, L., Dabin, L. C., Park, J. H., Hartigan, K. A., Kersey, H. N., Mesecar, M. E., Gibbs, J. R., Cookson, M. R., et al. (2026) · bioRxiv

Single-cell and spatial transcriptomicsCell Image Analysis Techniques

Cited by 0