Humphries, Steve E.

Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk

Humphries, S. E., Whittall, R. A., Hubbart, C. S., Maplebeck, S., Cooper, J. A., Soutar, A. K., Naoumova, R., Thompson, G. R., Seed, M., Durrington, P. N., et al. (2006) · Journal of Medical Genetics

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 267

Coronary calcium measurement improves prediction of cardiovascular events in asymptomatic patients with type 2 diabetes: the PREDICT study

Elkeles, R. S., Godsland, I. F., Feher, M. D., Rubens, M. B., Roughton, M., Nugara, F., Humphries, S. E., Richmond, W., Flather, M. D., & for the PREDICT Study Group (2008) · European Heart Journal

Cardiac Imaging and DiagnosticsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 261

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

Boldt, K., van Reeuwijk, J., Lu, Q., Koutroumpas, K., Nguyen, T.-M. T., Texier, Y., van Beersum, S. E. C., Horn, N., Willer, J. R., Mans, D. A., et al. (2016) · Nature Communications

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 240

Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries

Futema, M., Shah, S., Cooper, J. A., Li, K., Whittall, R. A., Sharifi, M., Goldberg, O., Drogari, E., Mollaki, V., Wiegman, A., et al. (2015) · Clinical Chemistry

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 213

Low-grade inflammation may play a role in the etiology of the metabolic syndrome in patients with coronary heart disease: the HIFMECH Study

Yudkin, J. S., Juhan-Vague, I., Hawe, E., Humphries, S. E., di Minno, G., Margaglione, M., Tremoli, E., Kooistra, T., Morange, P. E., Lundman, P., et al. (2004) · Metabolism

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 153

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.

White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., Shah, S., Kruger, F. A., Giambartolomei, C., Swerdlow, D. I., et al. (2016) · The Lancet Diabetes & Endocrinology

Gout, Hyperuricemia, Uric AcidGenetic Associations and Epidemiology

Cited by 132

Whole-genome sequence-based analysis of thyroid function

Taylor, P. N., Porcu, E., Chew, S., Campbell, P. J., Traglia, M., Brown, S. J., Mullin, B. H., Shihab, H. A., Min, J., Walter, K., et al. (2015) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 104

Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms

Sofat, R., Hingorani, A. D., Smeeth, L., Humphries, S. E., Talmud, P. J., Cooper, J., Shah, T., Sandhu, M. S., Ricketts, S. L., Boekholdt, S. M., et al. (2010) · Circulation

Lipoproteins and Cardiovascular HealthParaoxonase enzyme and polymorphisms

Cited by 104

LDL cholesterol-raising effect of low-dose docosahexaenoic acid in middle-aged men and women.

Theobald, H. E., Chowienczyk, P. J., Whittall, R., Humphries, S. E., & Sanders, T. A. (2004) · The American Journal of Clinical Nutrition

Fatty Acid Research and HealthLipoproteins and Cardiovascular Health

Cited by 101

A genome-wide association study identifies multiple loci for variation in human ear morphology

Adhikari, K., Reales, G., Smith, A. J. P., Konka, E., Palmen, J., Quinto-Sanchez, M., Acuña-Alonzo, V., Jaramillo, C., Arias, W., Fuentes, M., et al. (2015) · Nature Communications

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 95

Bone structure and geometry in young men: The influence of smoking, alcohol intake and physical activity

Eleftheriou, K. I., Rawal, J. S., James, L. E., Payne, J. R., Loosemore, M., Pennell, D. J., World, M., Drenos, F., Haddad, F. S., Humphries, S. E., et al. (2013) · Bone

Bone health and osteoporosis researchHIV-related health complications and treatments

Cited by 74

Utility of genetic determinants of lipids and cardiovascular events in assessing risk

Holmes, M. V., Harrison, S., Talmud, P. J., Hingorani, A. D., & Humphries, S. E. (2011) · Nature Reviews Cardiology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 44

Development of a high-resolution melting method for mutation detection in familial hypercholesterolaemia patients

Whittall, R. A., Scartezini, M., Li, K., Hubbart, C., Reiner, Z., Abraha, A., Neil, H. A. W., Dedoussis, G., & Humphries, S. E. (2010) · Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

Lipoproteins and Cardiovascular HealthGenomics and Rare Diseases

Cited by 43

Circulating apolipoprotein E concentration and cardiovascular disease risk: meta-analysis of results from three studies

Sofat, R., Cooper, J. A., Kumari, M., Casas, J. P., Mitchell, J. P., Acharya, J., Thom, S., Hughes, A. D., Humphries, S. E., & Hingorani, A. D. (2016) · PLOS Medicine

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 42

Three Novel Mutations in the Apolipoprotein E Gene in a Sample of Individuals with Type 2 Diabetes Mellitus

Stephens, J. W., Sozen, M. M., Whittall, R. A., Caslake, M. J., Bedford, D., Acharya, J., Hurel, S. J., & Humphries, S. E. (2005) · Clinical Chemistry

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 9