Neumann, Harald

Microglia states and nomenclature: A field at its crossroads

Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., et al. (2022) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,973

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

Zhang, B., Gaiteri, C., Bodea, L.-G., Wang, Z., McElwee, J., Podtelezhnikov, A. A., Zhang, C., Xie, T., Tran, L., Dobrin, R., et al. (2013) · Cell

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 1,657

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2

Takahashi, K., Rochford, C. D. P., & Neumann, H. (2005) · The Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 1,124

Debris clearance by microglia: an essential link between degeneration and regeneration

Neumann, H., Kotter, M. R., & Franklin, R. J. M. (2008) · Brain

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 1,111

Neuronal ‘On’ and ‘Off’ signals control microglia

Biber, K., Neumann, H., Inoue, K., & Boddeke, H. W. G. M. (2007) · Trends in Neurosciences

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 787

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis

Sierra, A., Abiega, O., Shahraz, A., & Neumann, H. (2013) · Frontiers in Cellular Neuroscience

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 574

TREM2-Transduced Myeloid Precursors Mediate Nervous Tissue Debris Clearance and Facilitate Recovery in an Animal Model of Multiple Sclerosis

Takahashi, K., Prinz, M., Stagi, M., Chechneva, O., & Neumann, H. (2007) · PLoS Medicine

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 414

Control of glial immune function by neurons

Neumann, H. (2001) · Glia

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 319

Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage

Wunderlich, P., Glebov, K., Kemmerling, N., Tien, N. T., Neumann, H., & Walter, J. (2013) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 296

Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis

Neumann, H., & Takahashi, K. (2007) · Journal of Neuroimmunology

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 249

Neurodegeneration by Activation of the Microglial Complement-Phagosome Pathway

Bodea, L.-G., Wang, Y., Linnartz-Gerlach, B., Kopatz, J., Sinkkonen, L., Musgrove, R., Kaoma, T., Muller, A., Vallar, L., Di Monte, D. A., et al. (2014) · Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 234

Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9)

Iliev, A. I., Stringaris, A. K., Nau, R., & Neumann, H. (2004) · The FASEB Journal

Neuroinflammation and Neurodegeneration MechanismsImmune Response and Inflammation

Cited by 192

Variant TREM2 as Risk Factor for Alzheimer's Disease

Neumann, H., & Daly, M. J. (2013) · New England Journal of Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 177

Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis

Garcia-Reitboeck, P., Phillips, A., Piers, T. M., Villegas-Llerena, C., Butler, M., Mallach, A., Rodrigues, C., Arber, C. E., Heslegrave, A., Zetterberg, H., et al. (2018) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 162

Accumulation of tau induced in neurites by microglial proinflammatory mediators

Gorlovoy, P., Larionov, S., Pham, T. T. H., & Neumann, H. (2009) · The FASEB Journal

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 156

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

Clarner, T., Janssen, K., Nellessen, L., Stangel, M., Skripuletz, T., Krauspe, B., Hess, F.-M., Denecke, B., Beutner, C., Linnartz-Gerlach, B., et al. (2015) · The Journal of Immunology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 150

Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia

Linnartz, B., Kopatz, J., Tenner, A. J., & Neumann, H. (2012) · The Journal of Neuroscience

Complement system in diseasesGlycosylation and Glycoproteins Research

Cited by 134

Unique transcriptome signature of mouse microglia

Beutner, C., Linnartz‐Gerlach, B., Schmidt, S. V., Beyer, M., Mallmann, M. R., Staratschek‐Jox, A., Schultze, J. L., & Neumann, H. (2013) · Glia

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 112

TREM2 triggers microglial density and age-related neuronal loss

Linnartz‐Gerlach, B., Bodea, L., Klaus, C., Ginolhac, A., Halder, R., Sinkkonen, L., Walter, J., Colonna, M., & Neumann, H. (2019) · Glia

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 104

Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst

Claude, J., Linnartz-Gerlach, B., Kudin, A. P., Kunz, W. S., & Neumann, H. (2013) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsGlycosylation and Glycoproteins Research

Cited by 98

Microglial Immunoreceptor Tyrosine-Based Activation and Inhibition Motif Signaling in Neuroinflammation

Linnartz, B., Wang, Y., & Neumann, H. (2010) · International Journal of Alzheimer's Disease

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 87

Generation of microglial cells from mouse embryonic stem cells

Beutner, C., Roy, K., Linnartz, B., Napoli, I., & Neumann, H. (2010) · Nature Protocols

Neuroinflammation and Neurodegeneration MechanismsPluripotent Stem Cells Research

Cited by 85

Sensing the neuronal glycocalyx by glial sialic acid binding immunoglobulin-like lectins

Linnartz-Gerlach, B., Mathews, M., & Neumann, H. (2014) · Neuroscience

Glycosylation and Glycoproteins ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 54

Brain microglia: watchdogs with pedigree

Neumann, H., & Wekerle, H. (2013) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 34