Generation of microglial cells from mouse embryonic stem cells

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Block, M. L., Zecca, L., & Hong, J.-S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2038 · Cited by 4,110 · see citing works

Microglia: Active sensor and versatile effector cells in the normal and pathologic brain

Hanisch, U.-K., & Kettenmann, H. (2007) · Nature Neuroscience · doi:10.1038/nn1997 · Cited by 3,676 · see citing works

Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation

Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960 · see citing works

Microglial physiology: unique stimuli, specialized responses

Ransohoff, R. M., & Perry, V. H. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132528 · Cited by 1,858 · see citing works

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

Ajami, B., Bennett, J. L., Krieger, C., Tetzlaff, W., & Rossi, F. M. V. (2007) · Nature Neuroscience · doi:10.1038/nn2014 · Cited by 1,643 · see citing works

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells

Lee, S.-H., Lumelsky, N., Studer, L., Auerbach, J., & Mckay, R. (2000) · Nature Biotechnology · doi:10.1038/76536 · Cited by 1,347 · see citing works

Immortalization of murine microglial cells by a v-raf / v-myc carrying retrovirus

Blasi, E., Barluzzi, R., Bocchini, V., Mazzolla, R., & Bistoni, F. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90073-v · Cited by 1,053 · see citing works

Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared

Ford, A. L., Goodsall, A. L., Hickey, W. F., & Sedgwick, J. D. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.154.9.4309 · Cited by 631 · see citing works

The origin and cell lineage of microglia: new concepts

Chan, W. Y., Kohsaka, S., & Rezaie, P. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.11.002 · Cited by 400 · cited 1× · see citing works

An immortalized cell line expresses properties of activated microglial cells

Bocchini, V., Mazzolla, R., Barluzzi, R., Blasi, E., Sick, P., & Kettenmann, H. (1992) · Journal of Neuroscience Research · doi:10.1002/jnr.490310405 · Cited by 364 · see citing works

Alternative versus Classical Activation of Macrophages

Goerdt, S., Politz, O., Schledzewski, K., Birk, R., Gratchev, A. N., Guillot, P., Hakiy, N., Klemke, C., Dippel, E., Kodelja, V., et al. (1999) · Pathobiology · doi:10.1159/000028096 · Cited by 324 · see citing works

Phagocytosis: Flow Cytometric Quantitation with Fluorescent Microspheres

Steinkamp, J. A., Wilson, J. S., Saunders, G. C., & Stewart, C. C. (1982) · Science · doi:10.1126/science.7053559 · Cited by 275 · see citing works

Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r–EGFP transgene reporter

Rae, F., Woods, K. J., Sasmono, R. T., Campanale, N., Taylor, D. F., Ovchinnikov, D. A., Grimmond, S. M., Hume, D. A., Ricardo, S. D., & Little, M. H. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.05.027 · Cited by 214 · see citing works

Laboratory Protocols for Conditional Gene Targeting

Torres, R. M., & Kühn, R. (1997) · doi:10.1093/oso/9780199636778.001.0001 · Cited by 170 · see citing works

Mouse resident microglia: Isolation and characterization of immunoregulatory properties with naïve CD4 and CD8 T‐cells

Havenith, C. E. G., Askew, D., & Walker, W. S. G. (1998) · Glia · doi:10.1002/(sici)1098-1136(199804)22:4 · Cited by 80 · see citing works

Microglial precursors derived from mouse embryonic stem cells

Napoli, I., Kierdorf, K., & Neumann, H. (2009) · Glia · doi:10.1002/glia.20878 · Cited by 49 · see citing works

Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma

Tsuchiya, T., Park, K. C., Toyonaga, S., Yamada, S. M., Nakabayashi, H., Nakai, E., Ikawa, N., Furuya, M., Tominaga, A., & Shimizu, K. (2004) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.10.025 · Cited by 45 · see citing works

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

Butovsky, O., Jedrychowski, M. P., Moore, C. S., Cialic, R., Lanser, A. J., Gabriely, G., Koeglsperger, T., Dake, B., Wu, P. M., Doykan, C. E., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3599 · Cited by 2,543 · see citing works

Microglia and macrophages in brain homeostasis and disease

Li, Q., & Barres, B. A. (2018) · Nature Reviews Immunology · doi:10.1038/nri.2017.125 · Cited by 1,999 · see citing works

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

Elmore, M. R. P., Najafi, A. R., Koike, M. A., Dagher, N. N., Spangenberg, E. E., Rice, R. A., Kitazawa, M., Matusow, B., Nguyen, H., West, B. L., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.040 · Cited by 1,968 · see citing works

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

Zhang, B., Gaiteri, C., Bodea, L.-G., Wang, Z., McElwee, J., Podtelezhnikov, A. A., Zhang, C., Xie, T., Tran, L., Dobrin, R., et al. (2013) · Cell · doi:10.1016/j.cell.2013.03.030 · Cited by 1,657 · see citing works

Microglia Biology: One Century of Evolving Concepts

Prinz, M., Jung, S., & Priller, J. (2019) · Cell · doi:10.1016/j.cell.2019.08.053 · Cited by 1,525 · see citing works

Microglial cell origin and phenotypes in health and disease

Saijo, K., & Glass, C. K. (2011) · Nature Reviews Immunology · doi:10.1038/nri3086 · Cited by 1,100 · see citing works

Efficient derivation of microglia-like cells from human pluripotent stem cells

Muffat, J., Li, Y., Yuan, B., Mitalipova, M., Omer, A., Corcoran, S., Bakiasi, G., Tsai, L.-H., Aubourg, P., Ransohoff, R. M., et al. (2016) · Nature Medicine · doi:10.1038/nm.4189 · Cited by 651 · see citing works

Microglia and Central Nervous System–Associated Macrophages—From Origin to Disease Modulation

Prinz, M., Masuda, T., Wheeler, M. A., & Quintana, F. J. (2021) · Annual Review of Immunology · doi:10.1146/annurev-immunol-093019-110159 · Cited by 584 · see citing works

The Indispensable Roles of Microglia and Astrocytes during Brain Development

Reemst, K., Noctor, S. C., Lucassen, P. J., & Hol, E. M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00566 · Cited by 516 · see citing works

Differentiation of human and murine induced pluripotent stem cells to microglia-like cells

Pandya, H., Shen, M. J., Ichikawa, D. M., Sedlock, A. B., Choi, Y., Johnson, K. R., Kim, G., Brown, M. A., Elkahloun, A. G., Maric, D., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4534 · Cited by 405 · see citing works

Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease

Balez, R., Steiner, N., Engel, M., Muñoz, S. S., Lum, J. S., Wu, Y., Wang, D., Vallotton, P., Sachdev, P. S., O’Connor, M. D., et al. (2016) · Scientific Reports · doi:10.1038/srep31450 · Cited by 278 · see citing works

An Overview of in vitro Methods to Study Microglia

Timmerman, R., Burm, S. M., & Bajramovic, J. J. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00242 · Cited by 222 · see citing works

Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis

Karlstetter, M., Nothdurfter, C., Aslanidis, A., Moeller, K., Horn, F., Scholz, R., Neumann, H., Weber, B. H. F., Rupprecht, R., & Langmann, T. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-3 · Cited by 216 · see citing works

Microglial immune checkpoint mechanisms

Deczkowska, A., Amit, I., & Schwartz, M. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0145-x · Cited by 185 · see citing works

Microglia-containing human brain organoids for the study of brain development and pathology

Zhang, W., Jiang, J., Xu, Z., Yan, H., Tang, B., Liu, C., Chen, C., & Meng, Q. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01892-1 · Cited by 188 · see citing works

Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems

Waisman, A., Ginhoux, F., Greter, M., & Bruttger, J. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.08.005 · Cited by 183 · see citing works

Cellular and Molecular Characterization of Microglia: A Unique Immune Cell Population

Sousa, C., Biber, K. P. H., & Michelucci, A. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00198 · Cited by 149 · see citing works

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

Clarner, T., Janssen, K., Nellessen, L., Stangel, M., Skripuletz, T., Krauspe, B., Hess, F.-M., Denecke, B., Beutner, C., Linnartz-Gerlach, B., et al. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1401459 · Cited by 150 · see citing works

Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cells

Hasselmann, J., & Blurton‐Jones, M. (2020) · Glia · doi:10.1002/glia.23781 · Cited by 145 · see citing works

Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia

Linnartz, B., Kopatz, J., Tenner, A. J., & Neumann, H. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3830-11.2012 · Cited by 134 · see citing works

Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia

Trudler, D., Nazor, K. L., Eisele, Y. S., Grabauskas, T., Dolatabadi, N., Parker, J., Sultan, A., Zhong, Z., Goodwin, M. S., Levites, Y., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2025847118 · Cited by 131 · see citing works

Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells

Mungenast, A. E., Siegert, S., & Tsai, L. (2015) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2015.11.010 · Cited by 127 · see citing works

Microglia: A Central Player in Depression

Deng, S.-L., Chen, J.-G., & Wang, F. (2020) · Current Medical Science · doi:10.1007/s11596-020-2193-1 · Cited by 119 · see citing works

Unique transcriptome signature of mouse microglia

Beutner, C., Linnartz‐Gerlach, B., Schmidt, S. V., Beyer, M., Mallmann, M. R., Staratschek‐Jox, A., Schultze, J. L., & Neumann, H. (2013) · Glia · doi:10.1002/glia.22524 · Cited by 100 · see citing works

Feeder-independent iPS cell derivation from human and mouse adipose stem cells

Sugii, S., Kida, Y. S., Berggren, W. T., & Evans, R. (2011) · Nature Protocols · doi:10.1038/nprot.2010.199 · Cited by 89 · see citing works

TREM2 triggers microglial density and age-related neuronal loss

Linnartz‐Gerlach, B., Bodea, L., Klaus, C., Ginolhac, A., Halder, R., Sinkkonen, L., Walter, J., Colonna, M., & Neumann, H. (2019) · Glia · doi:10.1002/glia.23563 · Cited by 104 · see citing works

Beta Interferon Controls West Nile Virus Infection and Pathogenesis in Mice

Lazear, H. M., Pinto, A. K., Vogt, M. R., Gale, M., & Diamond, M. (2011) · Journal of Virology · doi:10.1128/jvi.00396-11 · Cited by 104 · see citing works

Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator

Micklisch, S., Lin, Y., Jacob, S., Karlstetter, M., Dannhausen, K., Dasari, P., von der Heide, M., Dahse, H., Schmölz, L., Graßmann, F., et al. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0776-3 · Cited by 101 · see citing works

Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst

Claude, J., Linnartz-Gerlach, B., Kudin, A. P., Kunz, W. S., & Neumann, H. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.2211-13.2013 · Cited by 98 · see citing works

Polysialylation and lipopolysaccharide‐induced shedding of E‐selectin ligand‐1 and neuropilin‐2 by microglia and THP‐1 macrophages

Werneburg, S., Buettner, F. F. R., Erben, L., Mathews, M., Neumann, H., Mühlenhoff, M., & Hildebrandt, H. (2016) · Glia · doi:10.1002/glia.23004 · Cited by 91 · see citing works

3D culture of murine neural stem cells on decellularized mouse brain sections

Waele, J. D., Reekmans, K., Daans, J., Goossens, H., Berneman, Z. N., & Ponsaerts, P. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.11.025 · Cited by 92 · see citing works

Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina

Karlstetter, M., Kopatz, J., Aslanidis, A., Shahraz, A., Caramoy, A., Linnartz‐Gerlach, B., Lin, Y., Lückoff, A., Fauser, S., Düker, K., et al. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201606627 · Cited by 91 · see citing works

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation

Schmidt‐Pogoda, A., Strecker, J., Liebmann, M., Massoth, C., Beuker, C., Hansen, U. J., König, S., Albrecht, S., Böck, S., Breuer, J., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0209871 · Cited by 73 · see citing works

Siglec‐h on activated microglia for recognition and engulfment of glioma cells

Kopatz, J., Beutner, C., Welle, K., Bodea, L., Reinhardt, J., Claude, J., Linnartz‐Gerlach, B., & Neumann, H. (2013) · Glia · doi:10.1002/glia.22501 · Cited by 72 · see citing works

Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer’s Disease Therapeutic Target

Raikwar, S. P., Thangavel, R., Dubova, I., Selvakumar, G. P., Ahmed, M. E., Kempuraj, D., Zaheer, S. A., Iyer, S. S., & Zaheer, A. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1068-y · Cited by 66 · see citing works

Modelling microglial function with induced pluripotent stem cells: an update

Pocock, J. M., & Piers, T. M. (2018) · Nature reviews. Neuroscience · doi:10.1038/s41583-018-0030-3 · Cited by 57 · see citing works

Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia

Aslanidis, A., Karlstetter, M., Scholz, R., Fauser, S., Neumann, H., Fried, C., Pietsch, M., & Langmann, T. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0296-6 · Cited by 53 · see citing works

Induced Pluripotent Stem Cell Derived Macrophages as a Cellular System to Study Salmonella and Other Pathogens

Hale, C., Yeung, A. T. Y., Goulding, D., Pickard, D., Alasoo, K., Powrie, F. M., Gordon Dougan, B., & Mukhopadhyay, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124307 · Cited by 54 · see citing works

Concise Review: Modeling Neurodegenerative Diseases with Human Pluripotent Stem Cell-Derived Microglia

Haenseler, W., & Rajendran, L. (2019) · Stem Cells · doi:10.1002/stem.2995 · Cited by 54 · see citing works

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families

Pinto, A. K., Williams, G. D., Szretter, K. J., White, J. P., Proença‐Módena, J. L., Gai, L., Olejnik, J., Brien, J. D., Ebihara, H., Mühlberger, E., et al. (2015) · Journal of Virology · doi:10.1128/jvi.00996-15 · Cited by 51 · see citing works

Methamphetamine alters microglial immune function through P2X7R signaling

Fernandes, N. C., Sriram, U., Gofman, L., Cenna, J. M., Ramirez, S. H., & Potula, R. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0553-3 · Cited by 51 · see citing works

Induced pluripotent stem cells as a discovery tool for Alzheimer׳s disease

Sullivan, S. E., & Young-Pearse, T. L. (2017) · Brain Research · doi:10.1016/j.brainres.2015.10.005 · Cited by 50 · see citing works

Inhibition of Microglia Activation as a Phenotypic Assay in Early Drug Discovery

Figuera-Losada, M., Rojas, C. J., & Slusher, B. S. (2013) · SLAS DISCOVERY · doi:10.1177/1087057113499406 · Cited by 50 · see citing works

Activated microglia trigger inflammasome activation and lysosomal destabilization in human RPE cells

Nebel, C., Aslanidis, A., Rashid, K., & Langmann, T. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.01.176 · Cited by 42 · see citing works

P2X4 Receptor Regulates Alcohol-Induced Responses in Microglia

Gofman, L., Cenna, J. M., & Potula, R. (2014) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-014-9559-8 · Cited by 38 · see citing works

Microglia support neural stem cell maintenance and growth

Matsui, T. K., & Mori, E. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.07.130 · Cited by 36 · see citing works

Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease

García‐León, J. A., Cáceres-Palomo, L., Sánchez‐Mejías, E., Mejias‐Ortega, M., Nuñez‐Diaz, C., Fernandez-Valenzuela, J. J., Sanchez-Varo, R. M., Dávila, J. C., Vitórica, J., & Gutiérrez, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186867 · Cited by 35 · see citing works

Transnasal transplantation of human induced pluripotent stem cell‐derived microglia to the brain of immunocompetent mice

Parajuli, B., Saito, H., Shinozaki, Y., Shigetomi, E., Miwa, H., Yoneda, S., Tanimura, M., Omachi, S., Asaki, T., Takahashi, K., et al. (2021) · Glia · doi:10.1002/glia.23985 · Cited by 34 · see citing works

Regulation of Microglia Identity from an Epigenetic and Transcriptomic Point of View

Eggen, B. J. L., Boddeke, E. W. G. M., & Kooistra, S. M. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2017.12.010 · Cited by 25 · see citing works

Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells

Amos, P. J., Fung, S., Case, A., Kifelew, J., Osnis, L., Smith, C. S., Green, K., Naydenov, A. V., Aloi, M. S., Hubbard, J. J., et al. (2017) · ASN NEURO · doi:10.1177/1759091417716610 · Cited by 33 · see citing works

Engineered stem cell-derived microglia as therapeutic vehicle for experimental autoimmune encephalomyelitis

Beutner, C., Lepperhof, V., Dann, A., Linnartz‐Gerlach, B., Litwak, S. A., Napoli, I., Prinz, M., & Neumann, H. (2013) · Gene Therapy · doi:10.1038/gt.2012.100 · Cited by 32 · see citing works

Effects of Inflammasome Activation on Secretion of Inflammatory Cytokines and Vascular Endothelial Growth Factor by Retinal Pigment Epithelial Cells

Mohr, L. K. M., Hoffmann, A. V., Brandstetter, C., Holz, F. G., & Krohne, T. U. (2015) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.15-16898 · Cited by 30 · see citing works

Being human: The role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer's disease models

Sproul, A. A. (2015) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2015.06.007 · Cited by 30 · see citing works

An efficient method to limit microglia-dependent effects in astroglial cultures

Losciuto, S., Dorban, G., Gabel, S., Gustin, A., Hoenen, C., Grandbarbe, L., Heuschling, P., & Heurtaux, T. (2012) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2012.03.010 · Cited by 28 · see citing works

Murine iPSC-derived microglia and macrophage cell culture models recapitulate distinct phenotypical and functional properties of classical and alternative neuro-immune polarisation

Quarta, A., Blon, D. L., D’aes, T., Pieters, Z., Taj, S. H., Miró‐Mur, F., Luyckx, E., Breedam, E. V., Daans, J., Goossens, H., et al. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.09.009 · Cited by 28 · see citing works

Low molecular weight polysialic acid prevents lipopolysaccharide‐induced inflammatory dopaminergic neurodegeneration in humanized SIGLEC11 transgenic mice

Liao, H., Winkler, J., Wißfeld, J., Shahraz, A., Klaus, C., & Neumann, H. (2021) · Glia · doi:10.1002/glia.24073 · Cited by 26 · see citing works

Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell‐derived microglia

Beins, E. C., Ulas, T., Ternes, S., Neumann, H., Schultze, J. L., & Zimmer, A. (2016) · Glia · doi:10.1002/glia.22979 · Cited by 24 · see citing works

Evolving Models and Tools for Microglial Studies in the Central Nervous System

Zhang, Y., & Cui, D. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00706-8 · Cited by 23 · see citing works

Human stem cell models of dementia

Livesey, F. J. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu302 · Cited by 22 · see citing works

Relative Role of Akt, ERK and CREB in Alcohol-Induced Microglia P2X4R Receptor Expression

Gofman, L., Fernandes, N. C., & Potula, R. (2016) · Alcohol and Alcoholism · doi:10.1093/alcalc/agw009 · Cited by 22 · see citing works

Gene expression profiles of M1 and M2 microglia characterized by comparative analysis of public datasets

Satoh, J. (2017) · Clinical and Experimental Neuroimmunology · doi:10.1111/cen3.12426 · Cited by 22 · see citing works

Deconvolution of Human Brain Cell Type Transcriptomes Unraveled Microglia-Specific Potential Biomarkers

Ayana, R., Singh, S., & Pati, S. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00266 · Cited by 20 · see citing works

Intramembranous processing by γ‐secretase regulates reverse signaling of ephrin‐B2 in migration of microglia

Kemmerling, N., Wunderlich, P., Theil, S., Linnartz‐Gerlach, B., Hersch, N., Hoffmann, B., Heneka, M. T., Strooper, B. D., Neumann, H., & Walter, J. (2017) · Glia · doi:10.1002/glia.23147 · Cited by 20 · see citing works

Microglia in a Dish—Which Techniques Are on the Menu for Functional Studies?

Aktories, P., Petry, P., & Kierdorf, K. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.908315 · Cited by 16 · see citing works

Impact of colostrum and plasma immunoglobulin intake on hippocampus structure during early postnatal development in pigs

Pierzynowski, S. G., Ушакова, Г. А., Kovalenko, T., Osadchenko, I., Pierzynowska, K. G., Gustavsson, P., Prykhodko, O., Woliński, J., Słupecka‐Ziemilska, M., Ochniewicz, P., et al. (2014) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2014.03.003 · Cited by 17 · see citing works

Stem cells and Neurodegenerative Diseases: Where is it All Going?

Barker, R. A. (2012) · Regenerative Medicine · doi:10.2217/rme.12.64 · Cited by 16 · see citing works

Functional consequences of a close encounter between microglia and brain-infiltrating monocytes during CNS pathology and repair

Quarta, A., Berneman, Z. N., & Ponsaerts, P. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.3ru0820-536r · Cited by 16 · see citing works

Neuroimmunomodulatory properties of polysialic acid

Gretenkort, L., Thiesler, H., & Hildebrandt, H. (2023) · Glycoconjugate Journal · doi:10.1007/s10719-023-10120-z · Cited by 15 · see citing works

Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells

Ovchinnikov, D. A., & Wolvetang, E. J. (2014) · Journal of Clinical Medicine · doi:10.3390/jcm3041357 · Cited by 13 · see citing works

Activation of FXR pathway does not alter glial cell function

Albrecht, S., Fleck, A.-K., Kirchberg, I. E., Hucke, S., Liebmann, M., Klotz, L., & Kuhlmann, T. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-017-0833-6 · Cited by 11 · see citing works

Analogous modulation of inflammatory responses by the endocannabinoid system in periodontal ligament cells and microglia

Jäger, A., Setiawan, M. F., Beins, E. C., Schmidt‐Wolf, I. G. H., & Konermann, A. (2020) · Head & Face Medicine · doi:10.1186/s13005-020-00244-0 · Cited by 11 · see citing works

Emerging Models to Study Human Microglia In vitro

Jäntti, H., Kistemaker, L., Buonfiglioli, A., de Witte, L. D., Malm, T., & Hol, E. M. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-55529-9_30 · Cited by 8 · see citing works

Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system

Tribondeau, A., Sachs, L. M., & Buisine, N. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.996826 · Cited by 8 · see citing works

Parkinson’s Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson’s Disease, If Anything?

Drouin‐Ouellet, J., & Barker, R. (2012) · Stem Cells International · doi:10.1155/2012/926147 · Cited by 8 · see citing works

Two outward potassium current types are expressed during the neural differentiation of neural stem cells.

Bai, R., Gao, G.-W., Xing, Y., & Xue, H. (2013) · PubMed Central · doi:10.3969/j.issn.1673-5374.2013.28.008 · Cited by 5 · see citing works

Perspectives of Stem Cell-Derived Microglia for Medicine

Roy, K., Beutner, C., & Neum, H. (2011) · InTech eBooks · doi:10.5772/13850 · Cited by 3 · see citing works

Development and characterisation of mgTHP-1, a novel in vitro model for neural macrophages with microglial characteristics

Kodosaki, E., Daniels-Morgan, A., Hassan, N., Webb, R., Morris, K., & Kelly, C. (2023) · Neurological Research · doi:10.1080/01616412.2023.2257422 · Cited by 2 · see citing works

Ex vivo gene therapy for lysosomal storage disease using IPSC-derived neural stem cells

Griffin, T. A. (2015) · ScholarlyCommons (University of Pennsylvania)

Angefertigt mit Genehmigung der Mathematisch-Naturwissenschaftlichen Fakultät der

Bonn, R. F.-W.-U. (2012)

Rett Syndrome Induced Pluripotent Stem Cell-derived Neurons Exhibit Electrophysiological Aberrations

Farra, N. (2012) · TSpace (University of Toronto)

Establishment of polarized microglial cells derived from mouse embryonic stem cells

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Investigation of the endocannabinoid system using in vivo and in vitro models

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Establishment of microglial precursors derived from human induced pluripotent stem cells to model SOD1-mediated amyotrophic lateral sclerosis

Roy, K. (2013) · bonndoc (University of Bonn)

Oligodendrocytes as active modulators of neuroinflammation

Janssen, K., & Beyer, C. (2014) · RWTH Publications (RWTH Aachen)

Optimization of a neuron-microglia co-culture model to explore cell-to-cell interaction dynamics

Vogiatzis, S., Severa, M., Pietrantoni, A., Cairo, G., Falco, R. P., Veroni, C., Lanciotti, A., Etna, M. P., Abate, D. A., Nencioni, L., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1850795

Microglial precursors derived from mouse embryonic stem cells

Napoli, I., Kierdorf, K., & Neumann, H. (2009) · Glia · doi:10.1002/glia.20878 · Cited by 49 · see citing works

Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma

Tsuchiya, T., Park, K. C., Toyonaga, S., Yamada, S. M., Nakabayashi, H., Nakai, E., Ikawa, N., Furuya, M., Tominaga, A., & Shimizu, K. (2004) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.10.025 · Cited by 45 · see citing works

Establishment of Embryonic Stem Cell Derived Microglial Precursors and Application in an Animal Model of Alzheimer’s Disease

Napoli, I. (2008) · bonndoc (University of Bonn)

Establishment of polarized microglial cells derived from mouse embryonic stem cells

Ruegsegger, C. (2010) · Infoscience (Ecole Polytechnique Fédérale de Lausanne)

Microglia derived from embryonic stem cells and its application in CNS diseases

Beutner, C. (2012) · bonndoc (University of Bonn)