Seckl, Jonathan R.

Epigenetic programming by maternal behavior

Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience

Epigenetics and DNA MethylationStress Responses and Cortisol

Cited by 6,177

A transgenic model of visceral obesity and the metabolic syndrome

Masuzaki, H., Paterson, J., Shinyama, H., Morton, N. M., Mullins, J. J., Seckl, J. R., & Flier, J. S. (2001) · Science

Adipokines, Inflammation, and Metabolic DiseasesRegulation of Appetite and Obesity

Cited by 1,766

Prenatal stress, glucocorticoids and the programming of the brain

Welberg, L. A. M., & Seckl, J. R. (2001) · Journal of Neuroendocrinology

Stress Responses and CortisolBirth, Development, and Health

Cited by 928

11β-hydroxysteroid dehydrogenases: Intracellular gate-keepers of tissue glucocorticoid action

Chapman, K., Holmes, M., & Seckl, J. (2013) · Physiological Reviews

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 887

Early Environmental Regulation of Forebrain Glucocorticoid Receptor Gene Expression: Implications for Adrenocortical Responses to Stress; pp. 49–60

Meaney, M. J., Diorio, J., Francis, D., Widdowson, J., LaPlante, P., Caldji, C., Sharma, S., Seckl, J. R., & Plotsky, P. M. (2010) · Developmental Neuroscience

Stress Responses and CortisolNeuroendocrine regulation and behavior

Cited by 878

Glucocorticoids, prenatal stress and the programming of disease

Harris, A., & Seckl, J. (2011) · Hormones and Behavior

Birth, Development, and HealthStress Responses and Cortisol

Cited by 871

Mechanisms of Disease: glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology

Seckl, J. R., & Holmes, M. C. (2007) · Nature Clinical Practice Endocrinology & Metabolism

Birth, Development, and HealthStress Responses and Cortisol

Cited by 754

Transgenerational Effects of Posttraumatic Stress Disorder in Babies of Mothers Exposed to the World Trade Center Attacks during Pregnancy

Yehuda, R., Engel, S. M., Brand, S. R., Seckl, J., Marcus, S. M., & Berkowitz, G. S. (2005) · The Journal of Clinical Endocrinology & Metabolism

Posttraumatic Stress Disorder ResearchStress Responses and Cortisol

Cited by 711

Glucocorticoid Programming

SECKL, J. R., & MEANEY, M. J. (2004) · Annals of the New York Academy of Sciences

Birth, Development, and HealthStress Responses and Cortisol

Cited by 556

Adrenocortical, Autonomic, and Inflammatory Causes of the Metabolic Syndrome: Nested Case-Control Study

Brunner, E. J., Hemingway, H., Walker, B. R., Page, M., Clarke, P., Juneja, M., Shipley, M. J., Kumari, M., Andrew, R., Seckl, J. R., et al. (2002) · Circulation

Stress Responses and CortisolHeart Rate Variability and Autonomic Control

Cited by 539

Placental 11β‐hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure

Benediktsson, R., Calder, A. A., Edwards, C. R. W., & Seckl, J. R. (1997) · Clinical Endocrinology

Pregnancy and preeclampsia studiesBirth, Development, and Health

Cited by 536

Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

Morton, N. M., Paterson, J. M., Masuzaki, H., Holmes, M. C., Staels, B., Fievet, C., Walker, B. R., Flier, J. S., Mullins, J. J., & Seckl, J. R. (2004) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 512

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice

Masuzaki, H., Yamamoto, H., Kenyon, C. J., Elmquist, J. K., Morton, N. M., Paterson, J. M., Shinyama, H., Sharp, M. G. F., Fleming, S., Mullins, J. J., et al. (2003) · Journal of Clinical Investigation

Renin-Angiotensin System StudiesHormonal Regulation and Hypertension

Cited by 434

A RATIONAL APPROACH FOR ASSESSING THE HYPOTHALAMO-PITUITARY-ADRENAL AXIS

Stewart, P. M., Seckl, J. R., Corrie, J., Edwards, C. R. W., & Padfield, P. L. (1988) · The Lancet

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 418

Maternal stress alters endocrine function of the feto-placental unit in rats

Mairesse, J., Lesage, J., Breton, C., Bréant, B., Hahn, T., Darnaudéry, M., Dickson, S. L., Seckl, J., Blondeau, B., Vieau, D., et al. (2007) · American Journal of Physiology-Endocrinology and Metabolism

Birth, Development, and HealthStress Responses and Cortisol

Cited by 410

Changes in oxytocin and vasopressin secretion during sexual activity in men

MURPHY, M. R., SECKL, J. R., BURTON, S., CHECKLEY, S. A., & LIGHTMAN, S. L. (1987) · The Journal of Clinical Endocrinology & Metabolism

Neuroendocrine regulation and behaviorSexual function and dysfunction studies

Cited by 318

Glucocorticoids promote nonphlogistic phagocytosis of apoptotic leukocytes

Liu, Y., Cousin, J. M., Hughes, J., Van Damme, J., Seckl, J. R., Haslett, C., Dransfield, I., Savill, J., & Rossi, A. G. (1999) · The Journal of Immunology

Phagocytosis and Immune RegulationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 299

Minireview: Stress-related psychiatric disorders with low cortisol levels: A metabolic hypothesis

Yehuda, R., & Seckl, J. (2011) · Endocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 276

Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform.

Brown, R. W., Chapman, K. E., Edwards, C. R., & Seckl, J. R. (1993) · Endocrinology

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 271

Postnatal Handling Increases the Expression of cAMP-Inducible Transcription Factors in the Rat Hippocampus: The Effects of Thyroid Hormones and Serotonin

Meaney, M. J., Diorio, J., Francis, D., Weaver, S., Yau, J., Chapman, K., & Seckl, J. R. (2000) · The Journal of Neuroscience

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 266

Glucocorticoids, developmental ‘programming’ and the risk of affective dysfunction

Seckl, J. R. (2007) · Progress in Brain Research

Birth, Development, and HealthStress Responses and Cortisol

Cited by 245

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress

Wyrwoll, C. S., Holmes, M. C., & Seckl, J. R. (2011) · Frontiers in Neuroendocrinology

Stress Responses and CortisolHormonal Regulation and Hypertension

Cited by 244

Glucocorticoids and 11beta-Hydroxysteroid Dehydrogenase in Adipose Tissue

Seckl, J. R. (2004) · Recent Progress in Hormone Research

Adipokines, Inflammation, and Metabolic DiseasesHormonal Regulation and Hypertension

Cited by 239

Glucocorticoid “Programming” and PTSD Risk

SECKL, J. R., & MEANEY, M. J. (2006) · Annals of the New York Academy of Sciences

Birth, Development, and HealthStress Responses and Cortisol

Cited by 234