Prenatal stress, glucocorticoids and the programming of the brain

How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions

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How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions

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Place navigation impaired in rats with hippocampal lesions

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Fetal origins of coronary heart disease

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Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress

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Fetal and infant growth and impaired glucose tolerance at age 64

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The role of the amygdala in fear and anxiety

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The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis

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Neurocircuitry of stress: central control of the hypothalamo–pituitary–adrenocortical axis

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Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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The Role of the Hippocampus in Feedback Regulation of the Hypothalamic-Pituitary-Adrenocortical Axis*

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Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

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Glucose tolerance in adults after prenatal exposure to famine

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Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

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Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat

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The role of corticotropin-releasing factor in depression and anxiety disorders

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Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

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Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1

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Glucocorticoid exposure in utero: new model for adult hypertension

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Brain corticosteroid receptor balance and homeostatic control

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The association between prenatal stress and infant birth weight and gestational age at birth: a prospective investigation

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Prenatal Stress Induces High Anxiety and Postnatal Handling Induces Low Anxiety in Adult Offspring: Correlation with Stress-Induced Corticosterone Secretion

Vallée, M., Mayo, W., Dellu-Hagedorn, F., Moal, M. L., Simon, H., & Maccari, S. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-07-02626.1997 · Cited by 772 · see citing works

Schizophrenia After Prenatal Famine

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Cloning and tissue distribution of the human 1 lβ-hydroxysteroid dehydrogenase type 2 enzyme

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Increased Systolic Blood Pressure in Adult Rats Induced by Fetal Exposure to Maternal Low Protein Diets

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The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks gestation

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Maternal Glucocorticoid Secretion Mediates Long-Term Effects of Prenatal Stress

Barbazanges, A., Piazza, P., le Moal, M., & Maccari, S. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-12-03943.1996 · Cited by 655 · see citing works

Do early‐life events permanently alter behavioral and hormonal responses to stressors?

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Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning.

Oitzl, M. S., & de Kloet, E. R. (1992) · Behavioral Neuroscience · doi:10.1037//0735-7044.106.1.62 · Cited by 641 · see citing works

Fetal growth and coronary heart disease in South India

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Elevated Plasma Cortisol Concentrations: A Link between Low Birth Weight and the Insulin Resistance Syndrome?1

Phillips, D. I. W., Barker, D. J. P., Fall, C. H. D., Seckl, J. R., Whorwood, C. B., Wood, P. J., & Walker, B. R. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.3.4634 · Cited by 602 · see citing works

Mutations in the glucokinase gene of the fetus result in reduced birth weight

Hattersley, A. T., Beards, F., Ballantyne, E., Appleton, M., Harvey, R., & Ellard, S. (1998) · Nature Genetics · doi:10.1038/953 · Cited by 592 · see citing works

Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress

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Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring.

Nyirenda, M., Lindsay, R. S., Kenyon, C. J., Burchell, A. N., & Seckl, J. R. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1567 · Cited by 574 · see citing works

Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension?

Edwards, C. R. W., Benediktsson, R., Lindsay, R. S., & Seckl, J. R. (1993) · The Lancet · doi:10.1016/0140-6736(93)90148-a · Cited by 549 · see citing works

Does Prenatal Stress Impair Coping and Regulation of Hypothalamic-Pituitary-Adrenal Axis?

Weinstock, M. (1997) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(96)00014-0 · Cited by 539 · see citing works

Dexamethasone in the Last Week of Pregnancy Attenuates Hippocampal Glucocorticoid Receptor Gene Expression and Elevates Blood Pressure in the Adult Offspring in the Rat

Levitt, N. S., Lindsay, R. S., Holmes, M. C., & Seckl, J. R. (2008) · Neuroendocrinology · doi:10.1159/000127146 · Cited by 535 · see citing works

Prenatal Stress Increases the Hypothalamo‐Pituitary‐Adrenal Axis Response in Young and Adult Rats

Henry, C., Kabbaj, M., Simon, H., Moal, M. L., & Maccari, S. (1994) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1994.tb00591.x · Cited by 528 · see citing works

Prenatal exposure to maternal stress and subsequent schizophrenia

van Os, J., & Selten, J. (1998) · The British Journal of Psychiatry · doi:10.1192/bjp.172.4.324 · Cited by 481 · see citing works

On the Role of Brain Mineralocorticoid (Type I) and Glucocorticoid (Type II) Receptors in Neuroendocrine Regulation

Ratka, A., Sutanto, W., Bloemers, M., & de Kloet, E. R. (2008) · Neuroendocrinology · doi:10.1159/000125210 · Cited by 476 · see citing works

Sex-specific effects of prenatal stress on hypothalamic-pituitary-adrenal responses to stress and brain glucocorticoid receptor density in adult rats

McCormick, C. M., Smythe, J. W., Sharma, S., & Meaney, M. J. (1995) · Developmental Brain Research · doi:10.1016/0165-3806(94)00153-q · Cited by 471 · see citing works

Fetal and infant growth and cardiovascular risk factors in women

Fall, C. H. D., Osmond, C., Barker, D. J., Clark, P. M., Hales, C. N., Stirling, Y., & Meade, T. W. (1995) · BMJ · doi:10.1136/bmj.310.6977.428 · Cited by 461 · see citing works

Neonatal Handling Alters Adrenocortical Negative Feedback Sensitivity and Hippocampal Type II Glucocorticoid Receptor Binding in the Rat

Meaney, M. J., Aitken, D. H., Viau, V., Sharma, S., & Sarrieau, A. (2008) · Neuroendocrinology · doi:10.1159/000125287 · Cited by 457 · see citing works

Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase

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Impaired spatial and sequential learning in rats treated neonatally with d ‐fenfluramine

Morford, L. L., Inman-Wood, S. L., Gudelsky, G. A., Williams, M. T., & Vorhees, C. V. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02100.x · Cited by 454 · see citing works

Experience-dependent facilitating effect of corticosterone on spatial memory formation in the water maze

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Stress, Feedback and Facilitation in the Hypothalamo‐Pituitary‐Adrenal Axis

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Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat

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Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary adrenal system in the female rat

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Self-reported depression and negative pregnancy outcomes

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Corticosterone effects on corticotropin-releasing hormone mRNA in the central nucleus of the amygdala and the parvocellular region of the paraventricular nucleus of the hypothalamus

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Allostasis, amygdala, and anticipatory angst

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Long‐term effects of prenatal stress and postnatal handling on age‐related glucocorticoid secretion and cognitive performance: a longitudinal study in the rat

Vallée, M., Maccari, S., Dellu-Hagedorn, F., Simon, H., Moal, M. L., & Mayo, W. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00705.x · Cited by 378 · see citing works

Prenatal Loss of Father and Psychiatric Disorders

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Chronic Maternal Undernutrition in the Rat Leads to Delayed Postnatal Growth and Elevated Blood Pressure of Offspring

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Attenuated neuroendocrine responses to emotional and physical stressors in pregnant rats involve adenohypophysial changes

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Inhibition of 11β‐hydroxysteroid dehydrogenase, the foeto‐placental barrier to maternal glucocorticoids, permanently programs amygdala GR mRNA expression and anxiety‐like behaviour in the offspring

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Preterm delivery: effects of socioeconomic factors, psychological stress, smoking, alcohol, and caffeine

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Elevated Plasma Cortisol Concentrations: A Link between Low Birth Weight and the Insulin Resistance Syndrome?

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Purification and Characterization of the Corticosteroid 1lβ-Dehydrogenase Component of the Rat Liver 1lβ-Hydroxysteroid Dehydrogenase Complex*

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Sex Steroid Induced Changes in Hepatic Enzymes

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Inhibition of 11β-Hydroxysteroid Dehydrogenase in Pregnant Rats and the Programming of Blood Pressure in the Offspring

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The ontogeny of 11 beta-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development

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Glucocorticoids, feto-placental 11β-hydroxysteroid dehydrogenase type 2, and the early life origins of adult disease

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Effects of prenatal stress on vulnerability to stress in prepubertal and adult rats

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Maternal Deprivation Effect on the Infant’s Neural Stress Markers Is Reversed by Tactile Stimulation and Feeding But Not by Suppressing Corticosterone

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Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 b -hydroxysteroid dehydrogenase inhibitor carbenoxolone

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Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis.

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11Beta-hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction

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Impaired Glucose Tolerance and Elevated Blood Pressure in Low Birth Weight, Nonobese, Young South African Adults: Early Programming of Cortisol Axis1

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Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform.

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Maternal stress responses and anxiety during pregnancy: Effects on fetal heart rate

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Postnatal Handling Increases the Expression of cAMP-Inducible Transcription Factors in the Rat Hippocampus: The Effects of Thyroid Hormones and Serotonin

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Hypothalamic-Pituitary-Adrenal Response to Chronic Stress in Five Inbred Rat Strains: Differential Responses Are Mainly Located at the Adrenocortical Level

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The Metabolic Clearance Rate, Blood Production, Interconversion and Transplacental Passage of Cortisol and Cortisone in Pregnancy Near Term

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5'-Heterogeneity of Glucocorticoid Receptor Messenger RNA Is Tissue Specific: Differential Regulation of Variant Transcripts by Early-Life Events

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Antenatal corticosteroid therapy and blood pressure at 14 years of age in preterm children

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Biochemical effects of corticosteroids on neural tissues

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Passage of 14C-4-Corticosterone from the Rat Mother to the Foetus and Neonate

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Maternal stress induces synaptic loss and developmental disabilities of offspring

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Distinct Ontogeny of Glucocorticoid and Mineralocorticoid Receptor and 11β-Hydroxysteroid Dehydrogenase Types I and II mRNAs in the Fetal Rat Brain Suggest a Complex Control of Glucocorticoid Actions

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Prenatal dexamethasone causes oligonephronia, sodium retention, and higher blood pressure in the offspring

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Prenatal stress alters brain catecholaminergic activity and potentiates stress-induced behavior in adult rats

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The Amygdala: Corticotropin-Releasing Factor, Steroids, and Stress

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Maternal Protein Restriction Influences the Programming of the Rat Hypothalamic-Pituitary-Adrenal Axis

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