Seckl, Jonathan R.

The Mother or the Fetus? 11β-Hydroxysteroid Dehydrogenase Type 2 Null Mice Provide Evidence for Direct Fetal Programming of Behavior by Endogenous Glucocorticoids

Holmes, M. C., Abrahamsen, C. T., French, K. L., Paterson, J. M., Mullins, J. J., & Seckl, J. R. (2006) · The Journal of Neuroscience

Birth, Development, and HealthStress Responses and Cortisol

Cited by 200

Parental Posttraumatic Stress Disorder as a Vulnerability Factor for Low Cortisol Trait in Offspring of Holocaust Survivors

Yehuda, R., Teicher, M. H., Seckl, J. R., Grossman, R. A., Morris, A., & Bierer, L. M. (2007) · Archives of General Psychiatry

Stress Responses and CortisolPosttraumatic Stress Disorder Research

Cited by 195

11β-hydroxysteroid dehydrogenases: changing glucocorticoid action

Seckl, J. R. (2004) · Current Opinion in Pharmacology

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 185

Altered Placental Function of 11β-Hydroxysteroid Dehydrogenase 2 Knockout Mice

Wyrwoll, C. S., Seckl, J. R., & Holmes, M. C. (2009) · Endocrinology

Birth, Development, and HealthPregnancy and preeclampsia studies

Cited by 169

Foetal and placental 11 β‐HSD 2: a hub for developmental programming

Cottrell, E. C., Seckl, J. R., Holmes, M. C., & Wyrwoll, C. S. (2014) · Acta Physiologica

Birth, Development, and HealthPregnancy and preeclampsia studies

Cited by 123

How safe is long-term prenatal glucocorticoid treatment?

Seckl, J. R. (1997) · JAMA: The Journal of the American Medical Association

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 118

Reconciling the nutritional and glucocorticoid hypotheses of fetal programming

Cottrell, E. C., Holmes, M. C., Livingstone, D. E., Kenyon, C. J., & Seckl, J. R. (2012) · The FASEB Journal

Birth, Development, and HealthPregnancy and preeclampsia studies

Cited by 102

Omental 11β‐hydroxysteroid Dehydrogenase 1 Correlates with Fat Cell Size Independently of Obesity

Michailidou, Z., Jensen, M. D., Dumesic, D. A., Chapman, K. E., Seckl, J. R., Walker, B. R., & Morton, N. M. (2007) · Obesity

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 102

Smaller Left Anterior Cingulate Cortex Volumes Are Associated with Impaired Hypothalamic-Pituitary-Adrenal Axis Regulation in Healthy Elderly Men

MacLullich, A. M. J., Ferguson, K. J., Wardlaw, J. M., Starr, J. M., Deary, I. J., & Seckl, J. R. (2006) · The Journal of Clinical Endocrinology & Metabolism

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 100

Prenatal dexamethasone programs expression of genes in liver and adipose tissue and increased hepatic lipid accumulation but not obesity on a high-fat diet

Drake, A. J., Raubenheimer, P. J., Kerrigan, D., McInnes, K. J., Seckl, J. R., & Walker, B. R. (2010) · Endocrinology

Birth, Development, and HealthDiet, Metabolism, and Disease

Cited by 97

Enduring effects of severe developmental adversity, including nutritional deprivation, on cortisol metabolism in aging Holocaust survivors

Yehuda, R., Bierer, L. M., Andrew, R., Schmeidler, J., & Seckl, J. R. (2009) · Journal of Psychiatric Research

Stress Responses and CortisolBirth, Development, and Health

Cited by 90

Maternal high-fat diet acts as a stressor increasing maternal glucocorticoids’ signaling to the fetus and disrupting maternal behavior and brain activation in C57BL/6J mice

Bellisario, V., Panetta, P., Balsevich, G., Baumann, V., Noble, J., Raggi, C., Nathan, O., Berry, A., Seckl, J., Schmidt, M., et al. (2015) · Psychoneuroendocrinology

Neuroendocrine regulation and behaviorBirth, Development, and Health

Cited by 88

Ten Years on: Safety of Short Synacthen Tests in Assessing Adrenocorticotropin Deficiency in Clinical Practice

Gleeson, H. K., Walker, B. R., Seckl, J. R., & Padfield, P. L. (2003) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersPituitary Gland Disorders and Treatments

Cited by 85

Hypoglycemia due to an insulin-secreting small-cell carcinoma of the cervix.

Seckl, M. J., Mulholland, P. J., Bishop, A. E., Teale, J. D., Hales, C. N., Glaser, M., Watkins, S., & Seckl, J. R. (1999) · New England Journal of Medicine

Neuroendocrine Tumor Research AdvancesPancreatic function and diabetes

Cited by 75

Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women

Goedecke, J. H., Wake, D. J., Levitt, N. S., Lambert, E. V., Collins, M. R., Morton, N. M., Andrew, R., Seckl, J. R., & Walker, B. R. (2006) · Clinical Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 67

Higher systolic blood pressure is associated with increased water diffusivity in normal-appearing white matter

MacLullich, A. M. J., Ferguson, K. J., Reid, L. M., Deary, I. J., Starr, J. M., Seckl, J. R., Bastin, M. E., & Wardlaw, J. M. (2009) · Stroke

Advanced Neuroimaging Techniques and ApplicationsCerebrovascular and genetic disorders

Cited by 63

Epigenomic profiling of men exposed to early-life stress reveals DNA methylation differences in association with current mental state

Khulan, B., Manning, J. R., Dunbar, D. R., Seckl, J. R., Raikkonen, K., Eriksson, J. G., & Drake, A. J. (2014) · Translational Psychiatry

Epigenetics and DNA MethylationChild Abuse and Trauma

Cited by 59

Elevation of 11β-hydroxysteroid dehydrogenase type 2 activity in Holocaust survivor offspring: Evidence for an intergenerational effect of maternal trauma exposure

Bierer, L. M., Bader, H. N., Daskalakis, N. P., Lehrner, A. L., Makotkine, I., Seckl, J. R., & Yehuda, R. (2014) · Psychoneuroendocrinology

Stress Responses and CortisolPosttraumatic Stress Disorder Research

Cited by 57

The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice

Yau, J. L. W., Noble, J., Thomas, S., Kerwin, R., Morgan, P. E., Lightman, S., Seckl, J. R., & Pariante, C. M. (2007) · Neuropsychopharmacology

Stress Responses and CortisolDrug Transport and Resistance Mechanisms

Cited by 46

Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice

Yau, J. L. W., Wheelan, N., Noble, J., Walker, B. R., Webster, S. P., Kenyon, C. J., Ludwig, M., & Seckl, J. R. (2015) · Neurobiology of Aging

Memory and Neural MechanismsStress Responses and Cortisol

Cited by 45

Short-term administration of fluoxetine and venlafaxine decreases corticosteroid receptor mRNA expression in the rat hippocampus

Yau, J. L. W., Noble, J., Hibberd, C., & Seckl, J. R. (2001) · Neuroscience Letters

Stress Responses and CortisolTreatment of Major Depression

Cited by 43