Victor, Matheus B.

Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology

Mathys, H., Peng, Z., Boix, C. A., Victor, M. B., Leary, N., Babu, S., Abdelhady, G., Jiang, X., Ng, A. P., Ghafari, K., et al. (2023) · Cell

Alzheimer's disease research and treatmentsSingle-cell and spatial transcriptomics

Cited by 495

Human microglial state dynamics in Alzheimer’s disease progression

Sun, N., Victor, M. B., Park, Y. P., Xiong, X., Scannail, A. N., Leary, N., Prosper, S., Viswanathan, S., Luna, X., Boix, C. A., et al. (2023) · Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 462

Multisensory gamma stimulation promotes glymphatic clearance of amyloid

Murdock, M. H., Yang, C.-Y., Sun, N., Pao, P.-C., Blanco-Duque, C., Kahn, M. C., Kim, T., Lavoie, N. S., Victor, M. B., Islam, M. R., et al. (2024) · Nature

Cerebrospinal fluid and hydrocephalusAlzheimer's disease research and treatments

Cited by 379

Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity

Victor, M. B., Leary, N., Luna, X., Meharena, H. S., Scannail, A. N., Bozzelli, P. L., Samaan, G., Murdock, M. H., von Maydell, D., Effenberger, A. H., et al. (2022) · Cell Stem Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 316

Lipid Accumulation Induced by APOE4 Impairs Microglial Surveillance of Neuronal-Network Activity

Victor, M. B., Leary, N., Luna, X., Meharena, H. S., Bozzelli, P. L., Samaan, G., Murdock, M. H., von Maydell, D., Effenberger, A. H., Cerit, O., et al. (2022) · Cell stem cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 311

Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts

Victor, M. B., Richner, M., Hermanstyne, T. O., Ransdell, J. L., Sobieski, C., Deng, P.-Y., Klyachko, V. A., Nerbonne, J. M., & Yoo, A. S. (2014) · Neuron

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 295

Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

Blanchard, J. W., Bula, M., Davila-Velderrain, J., Akay, L. A., Zhu, L., Frank, A., Victor, M. B., Bonner, J. M., Mathys, H., Lin, Y.-T., et al. (2020) · Nature Medicine

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 283

Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes

Victor, M. B., Richner, M., Olsen, H. E., Lee, S. W., Monteys, A. M., Ma, C., Huh, C. J., Zhang, B., Davidson, B. L., Yang, X. W., et al. (2018) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

Cited by 246

Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts

Huh, C. J., Zhang, B., Victor, M. B., Dahiya, S., Batista, L. F., Horvath, S., & Yoo, A. S. (2016) · eLife

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 213

Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion

Xiong, X., James, B. T., Boix, C. A., Park, Y. P., Galani, K., Victor, M. B., Sun, N., Hou, L., Ho, L.-L., Mantero, J., et al. (2023) · Cell

Alzheimer's disease research and treatmentsGenomics and Chromatin Dynamics

Cited by 205

Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration

Welch, G. M., Boix, C. A., Schmauch, E., Davila-Velderrain, J., Victor, M. B., Dileep, V., Bozzelli, P. L., Su, Q., Cheng, J. D., Lee, A., et al. (2022) · Science Advances

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 84

Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy

Fox, L. M., Kim, K., Johnson, C. W., Chen, S., Croce, K. R., Victor, M. B., Eenjes, E., Bosco, J. R., Randolph, L. K., Dragatsis, I., et al. (2020) · Neuron

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 76