Sancak, Yasemin

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Sancak, Y., Peterson, T. R., Shaul, Y. D., Lindquist, R. A., Thoreen, C. C., Bar-Peled, L., & Sabatini, D. M. (2008) · Science

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,773

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Sancak, Y., Bar-Peled, L., Zoncu, R., Markhard, A. L., Nada, S., & Sabatini, D. M. (2010) · Cell

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 2,464

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H + -ATPase

Zoncu, R., Bar-Peled, L., Efeyan, A., Wang, S., Sancak, Y., & Sabatini, D. M. (2011) · Science

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 1,673

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

Sancak, Y., Thoreen, C. C., Peterson, T. R., Lindquist, R. A., Kang, S. A., Spooner, E., Carr, S. A., & Sabatini, D. M. (2007) · Molecular Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 1,236

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

Peterson, T. R., Laplante, M., Thoreen, C. C., Sancak, Y., Kang, S. A., Kuehl, W. M., Gray, N. S., & Sabatini, D. M. (2009) · Cell

PI3K/AKT/mTOR signaling in cancerMultiple Myeloma Research and Treatments

Cited by 1,202

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

Martell, J. D., Deerinck, T. J., Sancak, Y., Poulos, T. L., Mootha, V. K., Sosinsky, G. E., Ellisman, M. H., & Ting, A. Y. (2012) · Nature Biotechnology

Advanced Electron Microscopy Techniques and ApplicationsAdvanced Fluorescence Microscopy Techniques

Cited by 722

High-throughput identification of calcium-regulated proteins across diverse proteomes

Locke, T. M., Fields, R., Gizinski, H., Otto, G. M., MacEwen, M. J. S., Rusnac, D.-V., He, P., Shechner, D. M., McGann, C. D., Berg, M. D., et al. (2024) · Cell Reports

Advanced Proteomics Techniques and ApplicationsProtein Structure and Dynamics

Cited by 17