Reynolds, Richard

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

Howell, O. W., Reeves, C. A., Nicholas, R., Carassiti, D., Radotra, B., Gentleman, S. M., Serafini, B., Aloisi, F., Roncaroli, F., Magliozzi, R., et al. (2011) · Brain

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

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A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

Magliozzi, R., Howell, O. W., Reeves, C., Roncaroli, F., Nicholas, R., Serafini, B., Aloisi, F., & Reynolds, R. (2010) · Annals of Neurology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

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Neuronal vulnerability and multilineage diversity in multiple sclerosis

Schirmer, L., Velmeshev, D., Holmqvist, S., Kaufmann, M., Werneburg, S., Jung, D., Vistnes, S., Stockley, J. H., Young, A., Steindel, M., et al. (2019) · Nature

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 638

Exploring the origins of grey matter damage in multiple sclerosis

Calabrese, M., Magliozzi, R., Ciccarelli, O., Geurts, J. J. G., Reynolds, R., & Martin, R. (2015) · Nature Reviews Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 414

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis.

Choi, S. R., Howell, O. W., Carassiti, D., Magliozzi, R., Gveric, D., Muraro, P. A., Nicholas, R., Roncaroli, F., & Reynolds, R. (2012) · Brain

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 386

The role of gut dysbiosis in Parkinson’s disease: mechanistic insights and therapeutic options

Wang, Q., Luo, Y., Ray Chaudhuri, K., Reynolds, R., Tan, E.-K., & Pettersson, S. (2021) · Brain

Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health

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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Mancuso, R., Fryatt, G., Cleal, M., Obst, J., Pipi, E., Monzón-Sandoval, J., Ribe, E., Winchester, L., Webber, C., Nevado, A., et al. (2019) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 235

Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration

Quick, J. D., Silva, C., Wong, J. H., Lim, K. L., Reynolds, R., Barron, A. M., Zeng, J., & Lo, C. H. (2023) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 203

Substantial Archaeocortical Atrophy and Neuronal Loss in Multiple Sclerosis

Papadopoulos, D., Dukes, S., Patel, R., Nicholas, R., Vora, A., & Reynolds, R. (2009) · Brain Pathology

Multiple Sclerosis Research StudiesNeurological Disease Mechanisms and Treatments

Cited by 192

Increased PK11195 PET binding in the cortex of patients with MS correlates with disability

Politis, M., Giannetti, P., Su, P., Turkheimer, F., Keihaninejad, S., Wu, K., Waldman, A., Malik, O., Matthews, P. M., Reynolds, R., et al. (2012) · Neurology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 176

The response of NG2-expressing oligodendrocyte progenitors to demyelination in MOG-EAE and MS

Reynolds, R., Dawson, M., Papadopoulos, D., Polito, A., di Bello, I. C., Pham-Dinh, D., & Levine, J. (2002) · Journal of Neurocytology

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 175

Effects of Antemortem and Postmortem Variables on Human Brain mRNA Quality: A BrainNet Europe Study

Durrenberger, P. F., Fernando, S., Kashefi, S. N., Ferrer, I., Hauw, J.-J., Seilhean, D., Smith, C., Walker, R., Al-Sarraj, S., Troakes, C., et al. (2010) · Journal of Neuropathology & Experimental Neurology

Molecular Biology Techniques and ApplicationsRNA Research and Splicing

Cited by 161

Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis

Anderson, J. M., Hampton, D. W., Patani, R., Pryce, G., Crowther, R. A., Reynolds, R., Franklin, R. J. M., Giovannoni, G., Compston, D. A. S., Baker, D., et al. (2008) · Brain

Multiple Sclerosis Research StudiesAlzheimer's disease research and treatments

Cited by 141

Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat

Papadopoulos, D., Pham-Dinh, D., & Reynolds, R. (2006) · Experimental Neurology

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 115

Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

van Olst, L., Rodriguez-Mogeda, C., Picon, C., Kiljan, S., James, R. E., Kamermans, A., van der Pol, S. M. A., Knoop, L., Michailidou, I., Drost, E., et al. (2021) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

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The link between neuroinflammation and the neurovascular unit in synucleinopathies

Wang, Q., Zheng, J., Pettersson, S., Reynolds, R., & Tan, E.-K. (2023) · Science Advances

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

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Detection of Epstein–Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look

Aloisi, F., Serafini, B., Magliozzi, R., Howell, O. W., & Reynolds, R. (2010) · Brain

Multiple Sclerosis Research StudiesViral-associated cancers and disorders

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P2Y12 receptor protein in cortical gray matter lesions in multiple sclerosis.

Amadio, S., Montilli, C., Magliozzi, R., Bernardi, G., Reynolds, R., & Volonte, C. (2010) · Cerebral Cortex

Adenosine and Purinergic SignalingMultiple Sclerosis Research Studies

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Inflammatory Pathways in Parkinson’s Disease; A BNE Microarray Study

Durrenberger, P. F., Grünblatt, E., Fernando, F. S., Monoranu, C. M., Evans, J., Riederer, P., Reynolds, R., & Dexter, D. T. (2012) · Parkinson's Disease

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Absence of miRNA-146a Differentially Alters Microglia Function and Proteome

Martin, N. A., Hyrlov, K. H., Elkjaer, M. L., Thygesen, E. K., Wlodarczyk, A., Elbaek, K. J., Aboo, C., Okarmus, J., Benedikz, E., Reynolds, R., et al. (2020) · Frontiers in Immunology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

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Single-nucleus transcriptomics reveals a distinct microglial state and increased MSR1-mediated phagocytosis as common features across dementia subtypes

Chia, S.-Y., Li, M., Li, Z., Tu, H., Lee, J. W. L., Qiu, L., Ling, J., Reynolds, R., Albani, S., Tan, E.-K., et al. (2025) · Genome Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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