McCarthy, Mark I.

Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Chung, W. K., Erion, K., Florez, J. C., Hattersley, A. T., Hivert, M.-F., Lee, C. G., McCarthy, M. I., Nolan, J. J., Norris, J. M., Pearson, E. R., et al. (2020) · Diabetologia

Diabetes Management and ResearchDiabetes and associated disorders

Cited by 203

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., et al. (2013) · PLoS Medicine

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 203

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Saxena, R., Saleheen, D., Been, L. F., Garavito, M. L., Braun, T., Bjonnes, A., Young, R., Ho, W. K., Rasheed, A., Frossard, P., et al. (2013) · Diabetes

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 185

Global adiposity rather than abnormal regional fat distribution characterizes women with polycystic ovary syndrome

Barber, T. M., Golding, S. J., Alvey, C., Wass, J. A. H., Karpe, F., Franks, S., & McCarthy, M. I. (2008) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 179

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Mansour Aly, D., Dwivedi, O. P., Prasad, R. B., Käräjämäki, A., Hjort, R., Thangam, M., Åkerlund, M., Mahajan, A., Udler, M. S., Florez, J. C., et al. (2021) · Nature Genetics

Genetic Associations and EpidemiologyDiabetes and associated disorders

Cited by 172

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

Small, K. S., Todorčević, M., Civelek, M., El-Sayed Moustafa, J. S., Wang, X., Simon, M. M., Fernandez-Tajes, J., Mahajan, A., Horikoshi, M., Hugill, A., et al. (2018) · Nature Genetics

Adipokines, Inflammation, and Metabolic DiseasesGenetic Associations and Epidemiology

Cited by 168

Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

Viñuela, A., Varshney, A., van de Bunt, M., Prasad, R. B., Asplund, O., Bennett, A., Boehnke, M., Brown, A. A., Erdos, M. R., Fadista, J., et al. (2020) · Nature Communications

Genetic Associations and EpidemiologyPancreatic function and diabetes

Cited by 152

Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

Chung, K. M., Singh, J., Lawres, L., Dorans, K. J., Garcia, C., Burkhardt, D. B., Robbins, R., Bhutkar, A., Cardone, R., Zhao, X., et al. (2020) · Cell

Pancreatic and Hepatic Oncology ResearchCancer, Lipids, and Metabolism

Cited by 150

Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease

Hitman, G. A., Hawrami, K., McCarthy, M. I., Viswanathan, M., Snehalatha, C., Ramachandran, A., Tuomilehto, J., Tuomilehto-Wolf, E., Nissinen, A., & Pedersen, O. (1995) · Diabetologia

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 124

Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets

Travers, M. E., Mackay, D. J. G., Dekker Nitert, M., Morris, A. P., Lindgren, C. M., Berry, A., Johnson, P. R., Hanley, N., Groop, L. C., McCarthy, M. I., et al. (2013) · Diabetes

Genetic Syndromes and ImprintingPancreatic function and diabetes

Cited by 118

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Wood, A. R., Jonsson, A., Jackson, A. U., Wang, N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., et al. (2017) · Diabetes

Genetic Associations and EpidemiologyPancreatic function and diabetes

Cited by 117

Association of Genetic Loci With Glucose Levels in Childhood and Adolescence

Barker, A., Sharp, S. J., Timpson, N. J., Bouatia-Naji, N., Warrington, N. M., Kanoni, S., Beilin, L. J., Brage, S., Deloukas, P., Evans, D. M., et al. (2011) · Diabetes

Genetic Associations and EpidemiologyDiabetes and associated disorders

Cited by 117

Increased 5α-Reductase Activity and Adrenocortical Drive in Women with Polycystic Ovary Syndrome

Vassiliadi, D. A., Barber, T. M., Hughes, B. A., McCarthy, M. I., Wass, J. A. H., Franks, S., Nightingale, P., Tomlinson, J. W., Arlt, W., & Stewart, P. M. (2009) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersAdrenal Hormones and Disorders

Cited by 110

Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

Southam, L., Soranzo, N., Montgomery, S. B., Frayling, T. M., McCarthy, M. I., Barroso, I., & Zeggini, E. (2009) · Diabetologia

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 103

Predicting and elucidating the etiology of fatty liver disease: a machine learning modeling and validation study in the IMI DIRECT cohorts

Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Thomas, E. L., Koivula, R. W., Kurbasic, A., et al. (2020) · PLOS Medicine

Liver Disease Diagnosis and TreatmentAlcohol Consumption and Health Effects

Cited by 97

Meta-Analysis Investigating Associations Between Healthy Diet and Fasting Glucose and Insulin Levels and Modification by Loci Associated With Glucose Homeostasis in Data From 15 Cohorts

Nettleton, J. A., Hivert, M.-F., Lemaitre, R. N., McKeown, N. M., Mozaffarian, D., Tanaka, T., Wojczynski, M. K., Hruby, A., Djoussé, L., Ngwa, J. S., et al. (2013) · American Journal of Epidemiology

Nutrition, Genetics, and DiseaseNutritional Studies and Diet

Cited by 89

Distinct Variants at LIN28B Influence Growth in Height from Birth to Adulthood

Widén, E., Ripatti, S., Cousminer, D. L., Surakka, I., Lappalainen, T., Järvelin, M.-R., Eriksson, J. G., Raitakari, O., Salomaa, V., Sovio, U., et al. (2010) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyHypothalamic control of reproductive hormones

Cited by 88

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue

Drong, A. W., Nicholson, G., Hedman, Å. K., Meduri, E., Grundberg, E., Small, K. S., Shin, S.-Y., Bell, J. T., Karpe, F., Soranzo, N., et al. (2013) · PLoS ONE

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 79

Comparison of metabolic and inflammatory outcomes in women who used oral contraceptives and the levonorgestrel-releasing intrauterine device in a general population

Morin-Papunen, L., Martikainen, H., McCarthy, M. I., Franks, S., Sovio, U., Hartikainen, A.-L., Ruokonen, A., Leinonen, M., Laitinen, J., Järvelin, M.-R., et al. (2008) · American Journal of Obstetrics and Gynecology

Reproductive Health and ContraceptionDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 78

The impact of ethnicity on glucose regulation and the metabolic syndrome following gestational diabetes

Kousta, E., Efstathiadou, Z., Lawrence, N. J., Jeffs, J. A. R., Godsland, I. F., Barrett, S. C., Doré, C. J., Penny, A., Anyaoku, V., Millauer, B. A., et al. (2006) · Diabetologia

Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 74

A common biological basis of obesity and nicotine addiction

Thorgeirsson, T. E., Gudbjartsson, D. F., Sulem, P., Besenbacher, S., Styrkarsdottir, U., Thorleifsson, G., Walters, G. B., TAG Consortium, Oxford-GSK Consortium, ENGAGE consortium, et al. (2013) · Translational Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 71

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

Lim, E. T., Würtz, P., Havulinna, A. S., Palta, P., Tukiainen, T., Rehnström, K., Esko, T., Mägi, R., Inouye, M., Lappalainen, T., et al. (2014) · PLoS Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 49