Gutmann, David H.

The Somatic Genomic Landscape of Glioblastoma

Brennan, C. W., Verhaak, R. G. W., McKenna, A., Campos, B., Noushmehr, H., Salama, S. R., Zheng, S., Chakravarty, D., Sanborn, J. Z., Berman, S. H., et al. (2013) · Cell

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

Cited by 5,016

Microglia states and nomenclature: A field at its crossroads

Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., et al. (2022) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,973

The role of microglia and macrophages in glioma maintenance and progression

Hambardzumyan, D., Gutmann, D. H., & Kettenmann, H. (2016) · Nature Neuroscience

Immune cells in cancerGlioma Diagnosis and Treatment

Cited by 1,683

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

Yamanaka, K., Chun, S. J., Boillee, S., Fujimori-Tonou, N., Yamashita, H., Gutmann, D. H., Takahashi, R., Misawa, H., & Cleveland, D. W. (2008) · Nature Neuroscience

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 1,140

Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

Abeshouse, A., Adebamowo, C., Adebamowo, S. N., Akbani, R., Akeredolu, T., Ally, A., Anderson, M. L., Anur, P., Appelbaum, E. L., Armenia, J., et al. (2017) · Cell

Sarcoma Diagnosis and TreatmentChromatin Remodeling and Cancer

Cited by 1,069

Challenges to curing primary brain tumours

Aldape, K., Brindle, K. M., Chesler, L., Chopra, R., Gajjar, A., Gilbert, M. R., Gottardo, N., Gutmann, D. H., Hargrave, D., Holland, E. C., et al. (2019) · Nature Reviews Clinical Oncology

Glioma Diagnosis and TreatmentBrain Metastases and Treatment

Cited by 959

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.

Zeng, L., Xu, L., Gutmann, D. H., & Wong, M. (2008) · Annals of Neurology

Tuberous Sclerosis Complex ResearchEpilepsy research and treatment

Cited by 639

Astrocyte‐specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures

Uhlmann, E. J., Wong, M., Baldwin, R. L., Bajenaru, M. L., Onda, H., Kwiatkowski, D. J., Yamada, K., & Gutmann, D. H. (2002) · Annals of Neurology

Tuberous Sclerosis Complex ResearchEpilepsy research and treatment

Cited by 372

Oligodendroglial myelination requires astrocyte-derived lipids

Camargo, N., Goudriaan, A., van Deijk, A.-L. F., Otte, W. M., Brouwers, J. F., Lodder, H., Gutmann, D. H., Nave, K.-A., Dijkhuizen, R. M., Mansvelder, H. D., et al. (2017) · PLOS Biology

Neurogenesis and neuroplasticity mechanismsLipid metabolism and biosynthesis

Cited by 296

Nectin-like proteins mediate axon–Schwann cell interactions along the internode and are essential for myelination

Maurel, P., Einheber, S., Galinska, J., Thaker, P., Lam, I., Rubin, M. B., Scherer, S. S., Murakami, Y., Gutmann, D. H., & Salzer, J. L. (2007) · The Journal of Cell Biology

Neurogenesis and neuroplasticity mechanismsNerve injury and regeneration

Cited by 177

Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis

Stenzel, D., Lundkvist, A., Sauvaget, D., Busse, M., Graupera, M., van der Flier, A., Wijelath, E. S., Murray, J., Sobel, M., Costell, M., et al. (2011) · Development

Angiogenesis and VEGF in CancerAxon Guidance and Neuronal Signaling

Cited by 154

ABCA1 influences neuroinflammation and neuronal death

Karasinska, J. M., de Haan, W., Franciosi, S., Ruddle, P., Fan, J., Kruit, J. K., Stukas, S., Lütjohann, D., Gutmann, D. H., Wellington, C. L., et al. (2013) · Neurobiology of Disease

Neuroinflammation and Neurodegeneration MechanismsCholesterol and Lipid Metabolism

Cited by 104

RAS and beyond: the many faces of the neurofibromatosis type 1 protein

Anastasaki, C., Orozco, P., & Gutmann, D. H. (2022) · Disease Models & Mechanisms

Neurofibromatosis and Schwannoma CasesProtein Tyrosine Phosphatases

Cited by 86

MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models

Hoye, M. L., Koval, E. D., Wegener, A. J., Hyman, T. S., Yang, C., O'Brien, D. R., Miller, R. L., Cole, T., Schoch, K. M., Shen, T., et al. (2017) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchMicroRNA in disease regulation

Cited by 82

Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes

Bottelbergs, A., Verheijden, S., Hulshagen, L., Gutmann, D. H., Goebbels, S., Nave, K., Kassmann, C., & Baes, M. (2010) · Glia

Metabolism and Genetic DisordersHereditary Neurological Disorders

Cited by 78

Junctional Adhesion Molecules in Cancer: A Paradigm for the Diverse Functions of Cell–Cell Interactions in Tumor Progression

Lauko, A., Mu, Z., Gutmann, D. H., Naik, U. P., & Lathia, J. D. (2020) · Cancer Research

Cell Adhesion Molecules ResearchBarrier Structure and Function Studies

Cited by 72