Shirahige, Katsuhiko

Cohesin mediates transcriptional insulation by CCCTC-binding factor

Wendt, K. S., Yoshida, K., Itoh, T., Bando, M., Koch, B., Schirghuber, E., Tsutsumi, S., Nagae, G., Ishihara, K., Mishiro, T., et al. (2008) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,193

Cohesin relocation from sites of chromosomal loading to places of convergent transcription

Lengronne, A., Katou, Y., Mori, S., Yokobayashi, S., Kelly, G. P., Itoh, T., Watanabe, Y., Shirahige, K., & Uhlmann, F. (2004) · Nature

Genomics and Chromatin DynamicsMicrotubule and mitosis dynamics

Cited by 588

HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

Deardorff, M. A., Bando, M., Nakato, R., Watrin, E., Itoh, T., Minamino, M., Saitoh, K., Komata, M., Katou, Y., Clark, D., et al. (2012) · Nature

Genomics and Chromatin DynamicsDNA Repair Mechanisms

Cited by 577

Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries

Suzuki, T., Ota, Y., Ri, M., Bando, M., Gotoh, A., Itoh, Y., Tsumoto, H., Tatum, P. R., Mizukami, T., Nakagawa, H., et al. (2012) · Journal of Medicinal Chemistry

Histone Deacetylase Inhibitors ResearchClick Chemistry and Applications

Cited by 165

PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosine

Fujiki, K., Shinoda, A., Kano, F., Sato, R., Shirahige, K., & Murata, M. (2013) · Nature Communications

Epigenetics and DNA MethylationPeroxisome Proliferator-Activated Receptors

Cited by 123

Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence

Olan, I., Parry, A. J., Schoenfelder, S., Narita, M., Ito, Y., Chan, A. S. L., Slater, G. S. C., Bihary, D., Bando, M., Shirahige, K., et al. (2020) · Nature Communications

Genomics and Chromatin DynamicsTelomeres, Telomerase, and Senescence

Cited by 76

Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer

Miyata, K., Imai, Y., Hori, S., Nishio, M., Loo, T. M., Okada, R., Yang, L., Nakadai, T., Maruyama, R., Fujii, R., et al. (2021) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 74

Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8‐Selective Inhibitors

Suzuki, T., Muto, N., Bando, M., Itoh, Y., Masaki, A., Ri, M., Ota, Y., Nakagawa, H., Iida, S., Shirahige, K., et al. (2014) · ChemMedChem

Histone Deacetylase Inhibitors ResearchClick Chemistry and Applications

Cited by 71

Genome-Wide Target Analyses of Otx2 Homeoprotein in Postnatal Cortex

Sakai, A., Nakato, R., Ling, Y., Hou, X., Hara, N., Iijima, T., Yanagawa, Y., Kuwano, R., Okuda, S., Shirahige, K., et al. (2017) · Frontiers in Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 30

Different requirements for the association of ATR–ATRIP and 9-1-1 to the stalled replication forks

Kanoh, Y., Tamai, K., & Shirahige, K. (2006) · Gene

DNA Repair MechanismsFungal and yeast genetics research

Cited by 29