Bromley, Michael J.

Tackling the emerging threat of antifungal resistance to human health

Fisher, M. C., Alastruey-Izquierdo, A., Berman, J., Bicanic, T., Bignell, E. M., Bowyer, P., Bromley, M., Brüggemann, R., Garber, G., Cornely, O. A., et al. (2022) · Nature Reviews Microbiology

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 1,179

F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase

Oliver, J. D., Sibley, G. E. M., Beckmann, N., Dobb, K. S., Slater, M. J., McEntee, L., du Pré, S., Livermore, J., Bromley, M. J., Wiederhold, N. P., et al. (2016) · Proceedings of the National Academy of Sciences

Antifungal resistance and susceptibilityBiochemical and Molecular Research

Cited by 289

Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression

Beattie, S. R., Mark, K. M. K., Thammahong, A., Ries, L. N. A., Dhingra, S., Caffrey-Carr, A. K., Cheng, C., Black, C. C., Bowyer, P., Bromley, M. J., et al. (2017) · PLOS Pathogens

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 103

Aspergillus fumigatus strains that evolve resistance to the agrochemical fungicide ipflufenoquin in vitro are also resistant to olorofim

van Rhijn, N., Storer, I. S. R., Birch, M., Oliver, J. D., Bottery, M. J., & Bromley, M. J. (2023) · Nature Microbiology

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 86

The C 2 H 2 Transcription Factor SltA Contributes to Azole Resistance by Coregulating the Expression of the Drug Target Erg11A and the Drug Efflux Pump Mdr1 in Aspergillus fumigatus

Du, W., Zhai, P., Wang, T., Bromley, M. J., Zhang, Y., & Lu, L. (2021) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 46

MybA, a transcription factor involved in conidiation and conidial viability of the human pathogen Aspergillus fumigatus

Valsecchi, I., Sarikaya‐Bayram, Ö., Wong Sak Hoi, J., Muszkieta, L., Gibbons, J., Prevost, M., Mallet, A., Krijnse‐Locker, J., Ibrahim‐Granet, O., Mouyna, I., et al. (2017) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 35

Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target

Rhijn, N. V., Zhao, C., Al-Furaji, N., Storer, I., Valero, C., Gago, S., Chown, H., Baldin, C., Fortune-Grant, R., Shuraym, H. B., et al. (2023) · Nature Communications

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 30

Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging

van Rhijn, N., Zhao, C., Al-Furaiji, N., Storer, I. S. R., Valero, C., Gago, S., Chown, H., Baldin, C., Grant, R.-F., Bin Shuraym, H., et al. (2024) · Nature Communications

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 30

Elevated Levels of the Neutrophil Chemoattractant Pro–Platelet Basic Protein in Macrophages From Individuals With Chronic and Allergic Aspergillosis

Smith, N. L. D., Bromley, M. J., Denning, D. W., Simpson, A., & Bowyer, P. (2015) · The Journal of Infectious Diseases

Asthma and respiratory diseasesAntifungal resistance and susceptibility

Cited by 29

Aspergillus fumigatus Can Display Persistence to the Fungicidal Drug Voriconazole

Scott, J., Valero, C., Mato-López, Á., Donaldson, I. J., Roldán, A., Chown, H., Van Rhijn, N., Lobo-Vega, R., Gago, S., Furukawa, T., et al. (2023) · Microbiology Spectrum

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 24

The Caspofungin Paradoxical Effect is a Tolerant “Eagle Effect” in the Filamentous Fungal Pathogen Aspergillus fumigatus

Valero, C., Colabardini, A. C., de Castro, P. A., Amich, J., Bromley, M. J., & Goldman, G. H. (2022) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 23

Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus

Khateb, A., Gago, S., Bromley, M., Richardson, M., & Bowyer, P. (2023) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 14

Toward the consensus of definitions for the phenomena of antifungal tolerance and persistence in filamentous fungi

Amich, J., Bromley, M., Goldman, G. H., & Valero, C. (2025) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 14