Price, Alkes L.

Patterns of Cis Regulatory Variation in Diverse Human Populations

Stranger, B. E., Montgomery, S. B., Dimas, A. S., Parts, L., Stegle, O., Ingle, C. E., Sekowska, M., Smith, G. D., Evans, D., Gutierrez-Arcelus, M., et al. (2012) · PLoS Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 470

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Loh, P.-R., Bhatia, G., Gusev, A., Finucane, H. K., Bulik-Sullivan, B. K., Pollack, S. J., de Candia, T. R., Lee, S. H., Wray, N. R., et al. (2015) · Nature Genetics

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 449

Long-Range LD Can Confound Genome Scans in Admixed Populations

Price, A. L., Weale, M. E., Patterson, N., Myers, S. R., Need, A. C., Shianna, K. V., Ge, D., Rotter, J. I., Torres, E., Taylor, K. D., et al. (2008) · The American Journal of Human Genetics

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 443

Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations

Loh, P.-R., Genovese, G., Handsaker, R. E., Finucane, H. K., Reshef, Y. A., Palamara, P. F., Birmann, B. M., Talkowski, M. E., Bakhoum, S. F., McCarroll, S. A., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 423

Abundant contribution of short tandem repeats to gene expression variation in humans

Gymrek, M., Willems, T., Guilmatre, A., Zeng, H., Markus, B., Georgiev, S., Daly, M. J., Price, A. L., Pritchard, J. K., Sharp, A. J., et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 410

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

The PRACTICAL Consortium, Day, F. R., kConFab Investigators, AOCS Investigators, Scotland, G., EPIC-InterAct Consortium, Study, L. C., Ruth, K. S., Thompson, D. J., Lunetta, K. L., et al. (2015) · Nature Genetics

Genetic Associations and EpidemiologyBRCA gene mutations in cancer

Cited by 402

Distinguishing genetic correlation from causation across 52 diseases and complex traits

O’Connor, L. J., & Price, A. L. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 394

Exome sequencing and the genetic basis of complex traits

Kiezun, A., Garimella, K., Do, R., Stitziel, N. O., Neale, B. M., McLaren, P. J., Gupta, N., Sklar, P., Sullivan, P. F., Moran, J. L., et al. (2012) · Nature Genetics

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 372

Functionally informed fine-mapping and polygenic localization of complex trait heritability

Weissbrod, O., Hormozdiari, F., Benner, C., Cui, R., Ulirsch, J., Gazal, S., Schoech, A. P., van de Geijn, B., Reshef, Y., Márquez-Luna, C., et al. (2020) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 364

Fast and accurate long-range phasing in a UK Biobank cohort

Loh, P.-R., Palamara, P. F., & Price, A. L. (2016) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 342

Transethnic Genetic-Correlation Estimates from Summary Statistics

Brown, B. C., Ye, C. J., Price, A. L., & Zaitlen, N. (2016) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 340

Discerning the ancestry of European Americans in genetic association studies

Price, A. L., Butler, J., Patterson, N., Capelli, C., Pascali, V. L., Scarnicci, F., Ruiz-Linares, A., Groop, L., Saetta, A. A., Korkolopoulou, P., et al. (2008) · PLoS Genetics

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 327

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

Zhang, M. J., Hou, K., Dey, K. K., Sakaue, S., Jagadeesh, K. A., Weinand, K., Taychameekiatchai, A., Rao, P., Pisco, A. O., Zou, J., et al. (2022) · Nature Genetics

Single-cell and spatial transcriptomicsGenetic Associations and Epidemiology

Cited by 302

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Pasaniuc, B., Rohland, N., McLaren, P. J., Garimella, K., Zaitlen, N., Li, H., Gupta, N., Neale, B. M., Daly, M. J., Sklar, P., et al. (2012) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Phylogenetic Studies

Cited by 299

Adjusting for Heritable Covariates Can Bias Effect Estimates in Genome-Wide Association Studies

Aschard, H., Vilhjálmsson, B. J., Joshi, A. D., Price, A. L., & Kraft, P. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 287

A Genomewide Admixture Map for Latino Populations

Price, A. L., Patterson, N., Yu, F., Cox, D. R., Waliszewska, A., McDonald, G. J., Tandon, A., Schirmer, C., Neubauer, J., Bedoya, G., et al. (2007) · The American Journal of Human Genetics

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 282

Extreme Polygenicity of Complex Traits Is Explained by Negative Selection

O'Connor, L. J., Schoech, A. P., Hormozdiari, F., Gazal, S., Patterson, N., & Price, A. L. (2019) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 268

Quantitative analysis of population-scale family trees with millions of relatives

Kaplanis, J., Gordon, A., Shor, T., Weissbrod, O., Geiger, D., Wahl, M., Gershovits, M., Markus, B., Sheikh, M., Gymrek, M., et al. (2018) · Science

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 245

Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics

Jagadeesh, K. A., Dey, K. K., Montoro, D. T., Mohan, R., Gazal, S., Engreitz, J. M., Xavier, R. J., Price, A. L., & Regev, A. (2022) · Nature Genetics

Genetic Associations and EpidemiologySingle-cell and spatial transcriptomics

Cited by 239

Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity

Gazal, S., Weissbrod, O., Hormozdiari, F., Dey, K. K., Nasser, J., Jagadeesh, K. A., Weiner, D. J., Shi, H., Fulco, C. P., O’Connor, L. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 181

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection

Schoech, A. P., Jordan, D. M., Loh, P.-R., Gazal, S., O’Connor, L. J., Balick, D. J., Palamara, P. F., Finucane, H. K., Sunyaev, S. R., & Price, A. L. (2019) · Nature Communications

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 157

Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations

Gazal, S., Loh, P.-R., Finucane, H. K., Ganna, A., Schoech, A., Sunyaev, S., & Price, A. L. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 154

Progress and promise in understanding the genetic basis of common diseases

Price, A. L., Spencer, C. C. A., & Donnelly, P. (2015) · Proceedings of the Royal Society B: Biological Sciences

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 147

Population-specific causal disease effect sizes in functionally important regions impacted by selection

Shi, H., Gazal, S., Kanai, M., Koch, E. M., Schoech, A. P., Siewert, K. M., Kim, S. S., Luo, Y., Amariuta, T., Huang, H., et al. (2021) · Nature Communications

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 119