Demmers, Jeroen

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

Raj, V. S., Mou, H., Smits, S. L., Dekkers, D. H. W., Müller, M. A., Dijkman, R., Muth, D., Demmers, J. A. A., Zaki, A., Fouchier, R. A. M., et al. (2013) · Nature

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 2,061

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

Jaworski, J., Kapitein, L. C., Gouveia, S. M., Dortland, B. R., Wulf, P. S., Grigoriev, I., Camera, P., Spangler, S. A., Di Stefano, P., Demmers, J., et al. (2009) · Neuron

Neuroscience and Neuropharmacology ResearchMicrotubule and mitosis dynamics

Cited by 643

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

van den Berg, D. L. C., Snoek, T., Mullin, N. P., Yates, A., Bezstarosti, K., Demmers, J., Chambers, I., & Poot, R. A. (2010) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 542

TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites

van Spronsen, M., Mikhaylova, M., Lipka, J., Schlager, M. A., van den Heuvel, D. J., Kuijpers, M., Wulf, P. S., Keijzer, N., Demmers, J., Kapitein, L. C., et al. (2013) · Neuron

Microtubule and mitosis dynamicsMitochondrial Function and Pathology

Cited by 450

Rab6 regulates transport and targeting of exocytotic carriers

Grigoriev, I., Splinter, D., Keijzer, N., Wulf, P. S., Demmers, J., Ohtsuka, T., Modesti, M., Maly, I. V., Grosveld, F., Hoogenraad, C. C., et al. (2007) · Developmental Cell

Cellular transport and secretionExtracellular vesicles in disease

Cited by 361

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

Schwertman, P., Lagarou, A., Dekkers, D. H. W., Raams, A., van der Hoek, A. C., Laffeber, C., Hoeijmakers, J. H. J., Demmers, J. A. A., Fousteri, M., Vermeulen, W., et al. (2012) · Nature Genetics

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 279

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

Engelen, E., Akinci, U., Bryne, J. C., Hou, J., Gontan, C., Moen, M., Szumska, D., Kockx, C., van IJcken, W., Dekkers, D. H. W., et al. (2011) · Nature Genetics

Congenital Ear and Nasal AnomaliesDevelopmental Biology and Gene Regulation

Cited by 255

The core spliceosome as target and effector of non-canonical ATM signalling

Tresini, M., Warmerdam, D. O., Kolovos, P., Snijder, L., Vrouwe, M. G., Demmers, J. A. A., van IJcken, W. F. J., Grosveld, F. G., Medema, R. H., Hoeijmakers, J. H. J., et al. (2015) · Nature

RNA Research and SplicingDNA Repair Mechanisms

Cited by 252

Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia

Oosterhof, N., Chang, I. J., Karimiani, E. G., Kuil, L. E., Jensen, D. M., Daza, R., Young, E., Astle, L., van der Linde, H. C., Shivaram, G. M., et al. (2019) · The American Journal of Human Genetics

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 247

An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells

Lamers, M. M., van der Vaart, J., Knoops, K., Riesebosch, S., Breugem, T. I., Mykytyn, A. Z., Beumer, J., Schipper, D., Bezstarosti, K., Koopman, C. D., et al. (2021) · The EMBO Journal

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 227

A Proteome-wide Screen for Mammalian SxIP Motif-Containing Microtubule Plus-End Tracking Proteins

Jiang, K., Toedt, G., Montenegro Gouveia, S., Davey, N. E., Hua, S., van der Vaart, B., Grigoriev, I., Larsen, J., Pedersen, L. B., Bezstarosti, K., et al. (2012) · Current Biology

Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases

Cited by 209

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1–regulated pathways in mice

Meenhuis, A., van Veelen, P. A., de Looper, H., van Boxtel, N., van den Berge, I. J., Sun, S. M., Taskesen, E., Stern, P., de Ru, A. H., van Adrichem, A. J., et al. (2011) · Blood

MicroRNA in disease regulationAcute Myeloid Leukemia Research

Cited by 142

Proteomic analysis of the microenvironment of developing oocytes

Twigt, J., Steegers‐Theunissen, R. P., Bezstarosti, K., & Demmers, J. A. A. (2012) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsReproductive Biology and Fertility

Cited by 58

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism

Lu, X., Meima, M. E., Nelson, J. K., Sorrentino, V., Loregger, A., Scheij, S., Dekkers, D. H. W., Mulder, M. T., Demmers, J. A. A., M-Dallinga-Thie, G., et al. (2016) · Circulation Research

Renin-Angiotensin System StudiesCholesterol and Lipid Metabolism

Cited by 48

The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Llerena Schiffmacher, D. A., Lee, S.-H., Kliza, K. W., Theil, A. F., Akita, M., Helfricht, A., Bezstarosti, K., Gonzalo-Hansen, C., van Attikum, H., Verlaan-de Vries, M., et al. (2024) · Nature Communications

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 19

DDA1, a novel factor in transcription-coupled repair, modulates CRL4CSA dynamics at DNA damage-stalled RNA polymerase II

Pines, A., Schiffmacher, D. L., Lee, S.-H., Kliza, K., Theil, A., Akita, M., Helfricht, A., Bezstarosti, K., Gonzalo-Hansen, C., Attikum, H. V., et al. (2023) · Nature Communications

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 19

Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function

Avagliano Trezza, R., Punt, A. M., Mientjes, E., van den Berg, M., Zampeta, F. I., de Graaf, I. J., van der Weegen, Y., Demmers, J. A. A., Elgersma, Y., & Distel, B. (2021) · Scientific Reports

Ubiquitin and proteasome pathwaysCellular transport and secretion

Cited by 16

Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2

Pastoors, D., Havermans, M., Mulet-Lazaro, R., Brian, D., Noort, W., Grasel, J., Hoogenboezem, R., Smeenk, L., Demmers, J. A. A., Milsom, M. D., et al. (2024) · Science Advances

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 15