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The COP9 signalosome: A versatile regulatory hub of Cullin-RING ligases

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Mammalian DET1 Regulates Cul4A Activity and Forms Stable Complexes with E2 Ubiquitin-Conjugating Enzymes

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Dynamics of mammalian NER proteins

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Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair

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Accurate and Automated High-Coverage Identification of Chemically Cross-Linked Peptides with MaxLynx

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TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

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Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

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Different SWI/SNF complexes coordinately promote R-loop- and RAD52-dependent transcription-coupled homologous recombination

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Expression, Purification, and Characterization of the E1 for Human NEDD8, the Heterodimeric APPBP1–UBA3 Complex

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An immunoaffinity purification method for the proteomic analysis of ubiquitinated protein complexes

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Structural insights into DDA1 function as a core component of the CRL4-DDB1 ubiquitin ligase

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Identifying Nuclear Protein–Protein Interactions Using GFP Affinity Purification and SILAC-Based Quantitative Mass Spectrometry

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TFIIH central activity in nucleotide excision repair to prevent disease

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Inhibition of UVSSA ubiquitination suppresses transcription‐coupled nucleotide excision repair deficiency caused by dissociation from USP 7

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UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1

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Enhancing cryo-EM maps with 3D deep generative networks for assisting protein structure modeling

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Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

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Live cell transcription-coupled nucleotide excision repair dynamics revisited

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Detection of Protein Ubiquitination Sites by Peptide Enrichment and Mass Spectrometry

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STK19 positions TFIIH for cell-free transcription-coupled DNA repair

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STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment

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The molecular basis of human transcription-coupled DNA repair

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Mechanisms of transcription-coupled repair and DNA damage surveillance in health and disease

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ATP-Dependent Chromatin Remodeler CSB Couples DNA Repair Pathways to Transcription with Implications for Cockayne Syndrome and Cancer Therapy

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Transcription‐coupled repair: tangled up in convoluted repair

Schiffmacher, D. A. L., Pai, Y. J., Pines, A., & Vermeulen, W. (2025) · FEBS Journal · doi:10.1111/febs.70104 · Cited by 9 · see citing works

PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB–RNAPII complex

Robu, M., Shah, R. G., van den Heuvel, D., Coulombe, Y., Bazin, M., van der Woude, M., Kragten, A., Lans, H., Pascal, J. M., Masson, J., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf1303 · Cited by 6 · see citing works

STK19 drives Transcription-Coupled Repair by stimulating repair complex stability, Pol II ubiquitylation and TFIIH recruitmentPreprint

Ramadhin, A. R., Lee, S.-H., Zhou, D., Salmazo, A. P. T., Gonzalo-Hansen, C., van Sluis, M., Blom, C. M. A., Janssens, R. C., Raams, A., Dekkers, D. H. W., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.22.604556 · Cited by 3 · see citing works

Exploration of shared pathogenic factors and causative genes in early-stage endometrial cancer and osteoarthritis

Bai, Y., Luo, S., Shuai, R., Zhang, X., Yuan, L., & Liu, D. (2025) · Scientific Reports · doi:10.1038/s41598-025-04470-x · Cited by 2 · see citing works

Genomic homeostasis and congenital cranio-maxillofacial malformations

Pan, Z., Li, J., Wang, H., Lin, G., Zhang, X., & Dai, J. (2025) · Oral Science and Homeostatic Medicine · doi:10.26599/oshm.2025.9610008 · Cited by 2 · see citing works

RNA polymerase II processing facilitates DNA repair and prevents DNA damage-induced neuronal and developmental failurePreprint

van der Woude, M., Thijssen, K. L., Sabatella, M., Marteijn, J. A. F., Vermeulen, W., & Lans, H. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.21.644538 · Cited by 2 · see citing works

K63-linked ubiquitylation of S2P–RNAPII regulates transcription in a DNAPK inter-dependent manner in response to double-strand breaks

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Topology Resetting During Transcription-Coupled Nucleotide Excision Repair

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Targeting the COP9 signalosome overcomes platinum resistance in ovarian cancer through two distinct genome stability mechanismsPreprint

Lomonosova, E., Loeb, M., Rodriguez, K., van Biljon, L. N., Brill, J. D., Schab, A. M., Minett, M., Barron, J., Bittner, M., Park, J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.04.668450

Amino-Acid-mTORC1-Driven DDA1 Phosphorylation Promotes DNA Repair and Glioblastoma ProgressionPreprint

Peng, X., Chen, X., Wang, Z., An, Y., Liu, Y., Zhu, R., Li, L., Xu, D., Liu, R., Zhan, X., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-7717041/v1

Scalable insect cell expression and purification screening applied to CRL4-DCAF substrate receptors

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Transcription-coupled nucleotide excision repair protects against genomic instability and cell death induced by the liver toxin methyleugenol

Quarz, C., Walter, R. S., Hens, L. E., Carlsson, M. J., Vollmer, A. S., Schiffmacher, D. A. L., Pätzold, N., Ackermann, G., Heylmann, D., Stegmüller, S., et al. (2026) · Cell Death and Disease · doi:10.1038/s41419-026-08853-4

Amino-acids-mTORC1-driven DDA1 phosphorylation promotes DNA repair and glioblastoma progression

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RNA polymerase II removal: transcription quality control and gene regulation

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TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Pines, A., Dijk, M., Makowski, M. M., Meulenbroek, E. M., Vrouwe, M. G., van der Weegen, Y., Baltissen, M. P. A., French, P. J., van Royen, M. E., Luijsterburg, M. S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03484-6 · Cited by 48 · see citing works

Transcription-coupled DNA–protein crosslink repair by CSB and CRL4CSA-mediated degradation

van Sluis, M., Yu, Q. S., van der Woude, M., Gonzalo-Hansen, C., Dealy, S., Janssens, R. C., Somsen, H. B., Ramadhin, A. R., Dekkers, D. H. W., Wienecke, H. L., et al. (2024) · Nature Cell Biology · doi:10.1038/s41556-024-01394-y · Cited by 55 · see citing works

Live cell transcription-coupled nucleotide excision repair dynamics revisited

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The role of Cockayne syndrome group A (CSA) protein in transcription-coupled nucleotide excision repair

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STK19 drives Transcription-Coupled Repair by stimulating repair complex stability, Pol II ubiquitylation and TFIIH recruitmentPreprint

Ramadhin, A. R., Lee, S.-H., Zhou, D., Salmazo, A. P. T., Gonzalo-Hansen, C., van Sluis, M., Blom, C. M. A., Janssens, R. C., Raams, A., Dekkers, D. H. W., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.22.604556 · Cited by 3 · see citing works