Schuit, Frans

Chromosome instability is common in human cleavage-stage embryos

Vanneste, E., Voet, T., Le Caignec, C., Ampe, M., Konings, P., Melotte, C., Debrock, S., Amyere, M., Vikkula, M., Schuit, F., et al. (2009) · Nature Medicine

Prenatal Screening and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 880

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

Bouatia-Naji, N., Bonnefond, A., Cavalcanti-Proença, C., Sparsø, T., Holmkvist, J., Marchand, M., Delplanque, J., Lobbens, S., Rocheleau, G., Durand, E., et al. (2009) · Nature Genetics

Circadian rhythm and melatoninGenetic Associations and Epidemiology

Cited by 611

The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity

Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Geloen, A., Flamez, D., Mu, J., Lenzner, C., Baud, O., Bennoun, M., et al. (2003) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 499

Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression.

De Vos, A., Heimberg, H., Quartier, E., Huypens, P., Bouwens, L., Pipeleers, D., & Schuit, F. (1995) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 425

Metabolic Fate of Glucose in Purified Islet Cells

Schuit, F., De Vos, A., Farfari, S., Moens, K., Pipeleers, D., Brun, T., & Prentki, M. (1997) · Journal of Biological Chemistry

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 421

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

Chimienti, F., Devergnas, S., Pattou, F., Schuit, F., Garcia-Cuenca, R., Vandewalle, B., Kerr-Conte, J., Van Lommel, L., Grunwald, D., Favier, A., et al. (2006) · Journal of Cell Science

Pancreatic function and diabetesTrace Elements in Health

Cited by 349

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

Lemaire, K., Ravier, M. A., Schraenen, A., Creemers, J. W. M., Van de Plas, R., Granvik, M., Van Lommel, L., Waelkens, E., Chimienti, F., Rutter, G. A., et al. (2009) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesTrace Elements in Health

Cited by 330

Vitamin D Binding Protein: A Historic Overview

Bouillon, R., Schuit, F., Antonio, L., & Rastinejad, F. (2020) · Frontiers in Endocrinology

Vitamin D Research StudiesProtein Interaction Studies and Fluorescence Analysis

Cited by 316

Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, J. J., Schuit, F., & Drucker, D. J. (2004) · Diabetes

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 309

Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells

Schuit, F. C., In't Veld, P. A., & Pipeleers, D. G. (1988) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 308

Interleukin-6 regulates pancreatic α-cell mass expansion

Ellingsgaard, H., Ehses, J. A., Hammar, E. B., Van Lommel, L., Quintens, R., Martens, G., Kerr-Conte, J., Pattou, F., Berney, T., Pipeleers, D., et al. (2008) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 269

Redox Control of Exocytosis

Ivarsson, R., Quintens, R., Dejonghe, S., Tsukamoto, K., in ’t Veld, P., Renström, E., & Schuit, F. C. (2005) · Diabetes

Pancreatic function and diabetesRedox biology and oxidative stress

Cited by 265

Expression and Functional Activity of Glucagon, Glucagon-Like Peptide I, and Glucose-Dependent Insulinotropic Peptide Receptors in Rat Pancreatic Islet Cells

Moens, K., Heimberg, H., Flamez, D., Huypens, P., Quartier, E., Ling, Z., Pipeleers, D., Gremlich, S., Thorens, B., & Schuit, F. (1996) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 250

Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models

Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Flamez, D., Mu, J., Wojtaszewski, J. F. P., Schuit, F. C., Birnbaum, M., Richter, E., et al. (2003) · Biochemical Society Transactions

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 241

Differences in Glucose Transporter Gene Expression between Rat Pancreatic α- and β-Cells Are Correlated to Differences in Glucose Transport but Not in Glucose Utilization

Heimberg, H., De Vos, A., Pipeleers, D., Thorens, B., & Schuit, F. (1995) · Journal of Biological Chemistry

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 188

The Changes in Adenine Nucleotides Measured in Glucose-stimulated Rodent Islets Occur in β Cells but Not in α Cells and Are Also Observed in Human Islets

Detimary, P., Dejonghe, S., Ling, Z., Pipeleers, D., Schuit, F., & Henquin, J.-C. (1998) · Journal of Biological Chemistry

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 159

The glucose sensor protein glucokinase is expressed in glucagon-producing alpha-cells.

Heimberg, H., De Vos, A., Moens, K., Quartier, E., Bouwens, L., Pipeleers, D., Van Schaftingen, E., Madsen, O., & Schuit, F. (1996) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 142

Peroxisome proliferator-activated receptor-β signaling contributes to enhanced proliferation of hepatic stellate cells

Hellemans, K., Michalik, L., Dittie, A., Knorr, A., Rombouts, K., de Jong, J., Heirman, C., Quartier, E., Schuit, F., Wahli, W., et al. (2003) · Gastroenterology

Peroxisome Proliferator-Activated ReceptorsLiver physiology and pathology

Cited by 137

IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms

De Bruyne, E., Bos, T. J., Schuit, F., Van Valckenborgh, E., Menu, E., Thorrez, L., Atadja, P., Jernberg-Wiklund, H., & Vanderkerken, K. (2010) · Blood

Multiple Myeloma Research and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 103

Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids

Hellemans, K., Verbuyst, P., Quartier, E., Schuit, F., Rombouts, K., Chandraratna, R. A. S., Schuppan, D., & Geerts, A. (2004) · Hepatology

Liver physiology and pathologyRetinoids in leukemia and cellular processes

Cited by 102

Epidemiology, clinical aspects, and biology of IDDM patients under age 40 years. Comparison of data from Antwerp with complete ascertainment with data from Belgium with 40% ascertainment. The Belgian Diabetes Registry

Vandewalle, C. L., Coeckelberghs, M. I., De Leeuw, I. H., Caju, M. V. D., Schuit, F. C., Pipeleers, D. G., & Gorus, F. K. (1997) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 97

Nutrient regulation of gamma-aminobutyric acid release from islet beta cells

Smismans, A., Schuit, F., & Pipeleers, D. (1997) · Diabetologia

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 79

PPARβ regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation

Hellemans, K., Rombouts, K., Quartier, E., Dittié, A. S., Knorr, A., Michalik, L., Rogiers, V., Schuit, F., Wahli, W., & Geerts, A. (2003) · Journal of Lipid Research

Peroxisome Proliferator-Activated ReceptorsLiver physiology and pathology

Cited by 64

Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis

De Preter, V., Arijs, I., Windey, K., Vanhove, W., Vermeire, S., Schuit, F., Rutgeerts, P., & Verbeke, K. (2012) · Inflammatory Bowel Diseases

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 49