Locksley, Richard M.

The TNF and TNF Receptor Superfamilies

Locksley, R. M., Killeen, N., & Lenardo, M. J. (2001) · Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 3,650

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006) · Immunity

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 3,605

Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit

von Moltke, J., Ji, M., Liang, H.-E., & Locksley, R. M. (2016) · Nature

IL-33, ST2, and ILC PathwaysParasites and Host Interactions

Cited by 1,230

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

Nguyen, K. D., Qiu, Y., Cui, X., Goh, Y. P. S., Mwangi, J., David, T., Mukundan, L., Brombacher, F., Locksley, R. M., & Chawla, A. (2011) · Nature

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,038

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

Heredia, J. E., Mukundan, L., Chen, F. M., Mueller, A. A., Deo, R. C., Locksley, R. M., Rando, T. A., & Chawla, A. (2013) · Cell

Muscle Physiology and DisordersCardiac Fibrosis and Remodeling

Cited by 818

Interleukin-33 in tissue homeostasis, injury, and inflammation

Molofsky, A. B., Savage, A. K., & Locksley, R. M. (2015) · Immunity

IL-33, ST2, and ILC PathwaysMast cells and histamine

Cited by 638

Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

Nadjsombati, M. S., McGinty, J. W., Lyons-Cohen, M. R., Jaffe, J. B., DiPeso, L., Schneider, C., Miller, C. N., Pollack, J. L., Nagana Gowda, G. A., Fontana, M. F., et al. (2018) · Immunity

IL-33, ST2, and ILC PathwaysMast cells and histamine

Cited by 556

Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ

Jensen, K. D. C., Su, X., Shin, S., Li, L., Youssef, S., Yamasaki, S., Steinman, L., Saito, T., Locksley, R. M., Davis, M. M., et al. (2008) · Immunity

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 480

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

Schneider, C., O’Leary, C. E., von Moltke, J., Liang, H.-E., Ang, Q. Y., Turnbaugh, P. J., Radhakrishnan, S., Pellizzon, M., Ma, A., & Locksley, R. M. (2018) · Cell

IL-33, ST2, and ILC PathwaysParasites and Host Interactions

Cited by 478

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

Miller, C. N., Proekt, I., von Moltke, J., Wells, K. L., Rajpurkar, A. R., Wang, H., Rattay, K., Khan, I. S., Metzger, T. C., Pollack, J. L., et al. (2018) · Nature

T-cell and B-cell ImmunologyIon Channels and Receptors

Cited by 289

Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and γδ T cells

Van Dyken, S. J., Mohapatra, A., Nussbaum, J. C., Molofsky, A. B., Thornton, E. E., Ziegler, S. F., McKenzie, A. N. J., Krummel, M. F., Liang, H.-E., & Locksley, R. M. (2014) · Immunity

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 251

Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages

Voehringer, D., van Rooijen, N., & Locksley, R. M. (2007) · Journal of Leukocyte Biology

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 173

Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient

Hamadeh, R., Ardehali, A., Locksley, R. M., & York, M. K. (1988) · Chest

Antifungal resistance and susceptibilityFungal Infections and Studies

Cited by 151

Myristyl acylation of the tumor necrosis factor alpha precursor on specific lysine residues.

Stevenson, F. T., Bursten, S. L., Locksley, R. M., & Lovett, D. H. (1992) · The Journal of experimental medicine

Cytokine Signaling Pathways and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 117