Nawroth, Peter P.

RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

Yan, S. D., Chen, X., Fu, J., Chen, M., Zhu, H., Roher, A., Slattery, T., Zhao, L., Nagashima, M., Morser, J., et al. (1996) · Nature

Advanced Glycation End Products researchAlzheimer's disease research and treatments

Cited by 2,012

RAGE Mediates a Novel Proinflammatory Axis

Hofmann, M. A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., et al. (1999) · Cell

Advanced Glycation End Products researchS100 Proteins and Annexins

Cited by 1,864

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Deane, R., Du Yan, S., Submamaryan, R. K., LaRue, B., Jovanovic, S., Hogg, E., Welch, D., Manness, L., Lin, C., Yu, J., et al. (2003) · Nature Medicine

Alzheimer's disease research and treatmentsAdvanced Glycation End Products research

Cited by 1,426

Understanding RAGE, the receptor for advanced glycation end products

Bierhaus, A., Humpert, P. M., Morcos, M., Wendt, T., Chavakis, T., Arnold, B., Stern, D. M., & Nawroth, P. P. (2005) · Journal of Molecular Medicine

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 1,297

A mechanism converting psychosocial stress into mononuclear cell activation

Bierhaus, A., Wolf, J., Andrassy, M., Rohleder, N., Humpert, P. M., Petrov, D., Ferstl, R., von Eynatten, M., Wendt, T., Rudofsky, G., et al. (2003) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysStress Responses and Cortisol

Cited by 927

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

Hammes, H.-P., Du, X., Edelstein, D., Taguchi, T., Matsumura, T., Ju, Q., Lin, J., Bierhaus, A., Nawroth, P., Hannak, D., et al. (2003) · Nature Medicine

Advanced Glycation End Products researchRetinal Diseases and Treatments

Cited by 785

Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study

Zaharia, O. P., Strassburger, K., Strom, A., Bönhof, G. J., Karusheva, Y., Antoniou, S., Bódis, K., Markgraf, D. F., Burkart, V., Müssig, K., et al. (2019) · The Lancet Diabetes & Endocrinology

Diabetes and associated disordersDiabetes Management and Research

Cited by 600

Release of High Mobility Group Box 1 by Dendritic Cells Controls T Cell Activation via the Receptor for Advanced Glycation End Products

Dumitriu, I. E., Baruah, P., Valentinis, B., Voll, R. E., Herrmann, M., Nawroth, P. P., Arnold, B., Bianchi, M. E., Manfredi, A. A., & Rovere-Querini, P. (2005) · The Journal of Immunology

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 503

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes

Soro-Paavonen, A., Watson, A. M. D., Li, J., Paavonen, K., Koitka, A., Calkin, A. C., Barit, D., Coughlan, M. T., Drew, B. G., Lancaster, G. I., et al. (2008) · Diabetes

Advanced Glycation End Products researchAtherosclerosis and Cardiovascular Diseases

Cited by 407

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide

Yan, S. D., Yan, S. F., Chen, X., Fu, J., Chen, M., Kuppusamy, P., Smith, M. A., Perry, G., Godman, G. C., Nawroth, P., et al. (1995) · Nature Medicine

Alzheimer's disease research and treatmentsAdvanced Glycation End Products research

Cited by 406

DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury

Liesz, A., Dalpke, A., Mracsko, E., Roth, S., Zhou, W., Yang, H., Na, S.-Y., Akhisaroglu, M., Fleming, T., Eigenbrod, T., et al. (2015) · The Journal of Neuroscience

Advanced Glycation End Products researchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 334

Risk factors for incident diabetic polyneuropathy in a cohort with screen-detected type 2 diabetes followed for 13 years: ADDITION-Denmark

Andersen, S. T., Witte, D. R., Dalsgaard, E.-M., Andersen, H., Nawroth, P., Fleming, T., Jensen, T. M., Finnerup, N. B., Jensen, T. S., Lauritzen, T., et al. (2018) · Diabetes Care

Peripheral Neuropathies and DisordersPain Mechanisms and Treatments

Cited by 248

Glucose, Glycation, and RAGE: Implications for Amplification of Cellular Dysfunction in Diabetic Nephropathy

Wendt, T., Tanji, N., Guo, J., Hudson, B. I., Bierhaus, A., Ramasamy, R., Arnold, B., Nawroth, P. P., Yan, S. F., D’Agati, V., et al. (2003) · Journal of the American Society of Nephrology

Advanced Glycation End Products researchChronic Kidney Disease and Diabetes

Cited by 239

Regulation of osteoclast function and bone mass by RAGE

Zhou, Z., Immel, D., Xi, C.-X., Bierhaus, A., Feng, X., Mei, L., Nawroth, P., Stern, D. M., & Xiong, W.-C. (2006) · The Journal of Experimental Medicine

Bone Metabolism and DiseasesAdvanced Glycation End Products research

Cited by 178

Sustained Effects of a Mindfulness-Based Stress-Reduction Intervention in Type 2 Diabetic Patients

Hartmann, M., Kopf, S., Kircher, C., Faude-Lang, V., Djuric, Z., Augstein, F., Friederich, H.-C., Kieser, M., Bierhaus, A., Humpert, P. M., et al. (2012) · Diabetes Care

Mindfulness and Compassion InterventionsDiabetes Management and Education

Cited by 156

Relationship of Adiponectin with Markers of Systemic Inflammation, Atherogenic Dyslipidemia, and Heart Failure in Patients with Coronary Heart Disease

von Eynatten, M., Hamann, A., Twardella, D., Nawroth, P. P., Brenner, H., & Rothenbacher, D. (2006) · Clinical Chemistry

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 140

Dietary sugars, not lipids, drive hypothalamic inflammation

Gao, Y., Bielohuby, M., Fleming, T., Grabner, G. F., Foppen, E., Bernhard, W., Guzmán-Ruiz, M., Layritz, C., Legutko, B., Zinser, E., et al. (2017) · Molecular Metabolism

Neuroinflammation and Neurodegeneration MechanismsRegulation of Appetite and Obesity

Cited by 131

Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication

Loft, A., Alfaro, A. J., Schmidt, S. F., Pedersen, F. B., Terkelsen, M. K., Puglia, M., Chow, K. K., Feuchtinger, A., Troullinaki, M., Maida, A., et al. (2021) · Cell Metabolism

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 129

Impaired islet turnover in human donor pancreata with aging

Reers, C., Erbel, S., Esposito, I., Schmied, B., Büchler, M. W., Nawroth, P. P., & Ritzel, R. A. (2009) · European Journal of Endocrinology

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 113

Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)

Sandforth, A., von Schwartzenberg, R. J., Arreola, E. V., Hanson, R. L., Sancar, G., Katzenstein, S., Lange, K., Preißl, H., Dreher, S. I., Weigert, C., et al. (2023) · The Lancet Diabetes & Endocrinology

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 100

Vascular Endothelial Growth Factor (VEGF)-induced Up-regulation of CCN1 in Osteoblasts Mediates Proangiogenic Activities in Endothelial Cells and Promotes Fracture Healing

Athanasopoulos, A. N., Schneider, D., Keiper, T., Alt, V., Pendurthi, U. R., Liegibel, U. M., Sommer, U., Nawroth, P. P., Kasperk, C., & Chavakis, T. (2007) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchAngiogenesis and VEGF in Cancer

Cited by 99

A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis

Loft, A., Schmidt, S. F., Caratti, G., Stifel, U., Havelund, J., Sekar, R., Kwon, Y., Sulaj, A., Chow, K. K., Alfaro, A. J., et al. (2022) · Cell Metabolism

Dietary Effects on HealthPeroxisome Proliferator-Activated Receptors

Cited by 76

Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity

Teismann, P., Sathe, K., Bierhaus, A., Leng, L., Martin, H. L., Bucala, R., Weigle, B., Nawroth, P. P., & Schulz, J. B. (2012) · Neurobiology of Aging

Advanced Glycation End Products researchParkinson's Disease Mechanisms and Treatments

Cited by 75

Impaired Hepatic Mitochondrial Capacity in Nonalcoholic Steatohepatitis Associated With Type 2 Diabetes

Gancheva, S., Kahl, S., Pesta, D., Mastrototaro, L., Dewidar, B., Strassburger, K., Sabah, E., Esposito, I., Weiß, J., Sarabhai, T., et al. (2022) · Diabetes Care

Liver Disease Diagnosis and TreatmentMitochondrial Function and Pathology

Cited by 60