Grompe, Markus

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity

Paulk, N. K., Pekrun, K., Zhu, E., Nygaard, S., Li, B., Xu, J., Chu, K., Leborgne, C., Dane, A. P., Haft, A., et al. (2018) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 161

Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase

Hogema, B. M., Gupta, M., Senephansiri, H., Burlingame, T. G., Taylor, M., Jakobs, C., Schutgens, R. B. H., Froestl, W., Snead, O. C., Diaz-Arrastia, R., et al. (2001) · Nature Genetics

Metabolism and Genetic DisordersEpilepsy research and treatment

Cited by 157

A Single Mutation of the Fumarylacetoacetate Hydrolase Gene in French Canadians with Hereditary Tyrosinemia Type I

Grompe, M., St.-Louis, M., Demers, S. I., Al-Dhalimy, M., Leclerc, B., & Tanguay, R. M. (1994) · New England Journal of Medicine

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 135

Adeno‐associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo†‡

Paulk, N. K., Wursthorn, K., Wang, Z., Finegold, M. J., Kay, M. A., & Grompe, M. (2010) · Hepatology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 135

Long‐term therapy with NTBC and tyrosine‐restricted diet in a murine model of hereditary tyrosinemia type I

Al-Dhalimy, M., Overturf, K., Finegold, M., & Grompe, M. (2002) · Molecular Genetics and Metabolism

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 86

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

Jäkel, C., Bergmann, F., Toth, R., Assenov, Y., van der Duin, D., Strobel, O., Hank, T., Klöppel, G., Dorrell, C., Grompe, M., et al. (2017) · Nature Communications

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 69

Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase

Gibson, K. M., Schor, D. S. M., Gupta, M., Guerand, W. S., Senephansiri, H., Burlingame, T. G., Bartels, H., Hogema, B. M., Bottiglieri, T., Froestl, W., et al. (2002) · Journal of Neurochemistry

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 55

In vivo selection of wild‐type hematopoietic stem cells in a murine model of Fanconi anemia

Battaile, K. P., Bateman, R. L., Mortimer, D., Mulcahy, J., Rathbun, R. K., Bagby, G., Fleming, W. H., & Grompe, M. (1999) · Blood

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 54

Tissue Stem Cells: New Tools and Functional Diversity

Grompe, M. (2012) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 54

Helper‐independent and AAV‐ITR‐independent chromosomal integration of double‐stranded linear DNA vectors in mice

Nakai, H., Montini, E., Fuess, S., Storm, T. A., Meuse, L., Finegold, M., Grompe, M., & Kay, M. A. (2003) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 52

Murine succinate semialdehyde dehydrogenase deficiency

Gupta, M., Hogema, B. M., Grompe, M., Bottiglieri, T. G., Concas, A., Biggio, G., Sogliano, C., Rigamonti, A. E., Pearl, P. L., Snead, O. C., et al. (2003) · Annals of Neurology

Metabolism and Genetic DisordersEpilepsy research and treatment

Cited by 50

AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence

Wang, Z., Lisowski, L., Finegold, M. J., Nakai, H., Kay, M. A., & Grompe, M. (2012) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 44

Dynamic Transcriptional and Epigenetic Changes Drive Cellular Plasticity in the Liver

Merrell, A. J., Peng, T., Li, J., Sun, K., Li, B., Katsuda, T., Grompe, M., Tan, K., & Stanger, B. Z. (2021) · Hepatology

Liver physiology and pathologyTGF-β signaling in diseases

Cited by 42

Therapeutic Liver Reconstitution With Murine Cells Isolated Long After Death

Erker, L., Azuma, H., Lee, A. Y., Guo, C., Orloff, S., Eaton, L., Benedetti, E., Jensen, B., Finegold, M., Willenbring, H., et al. (2010) · Gastroenterology

Organ Transplantation Techniques and OutcomesLiver physiology and pathology

Cited by 34