Montine, Thomas J.

PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.

Jellinger, K. A., Alafuzoff, I., Attems, J., Beach, T. G., Cairns, N. J., Crary, J. F., Dickson, D. W., Hof, P. R., Hyman, B. T., Jack, C. R., et al. (2015) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 171

Clonal hematopoiesis is associated with protection from Alzheimer’s disease

Bouzid, H., Belk, J. A., Jan, M., Qi, Y., Sarnowski, C., Wirth, S., Ma, L., Chrostek, M. R., Ahmad, H., Nachun, D., et al. (2023) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 169

Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer’s disease mouse model

Herskowitz, J. H., Feng, Y., Mattheyses, A. L., Hales, C. M., Higginbotham, L. A., Duong, D. M., Montine, T. J., Troncoso, J. C., Thambisetty, M., Seyfried, N. T., et al. (2013) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 150

Lewy Body Pathology in Familial Alzheimer Disease: Evidence for Disease- and Mutation-Specific Pathologic Phenotype

Leverenz, J. B., Fishel, M. A., Peskind, E. R., Montine, T. J., Nochlin, D., Steinbart, E., Raskind, M. A., Schellenberg, G. D., Bird, T. D., & Tsuang, D. (2006) · Archives of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 139

Neuropathological and transcriptomic characteristics of the aged brain

Miller, J. A., Guillozet-Bongaarts, A., Gibbons, L. E., Postupna, N., Renz, A., Beller, A. E., Sunkin, S. M., Ng, L., Rose, S. E., Smith, K. A., et al. (2017) · eLife

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 134

A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology

Leverenz, J. B., Yu, C. E., Montine, T. J., Steinbart, E., Bekris, L. M., Zabetian, C., Kwong, L. K., Lee, V. M.-Y., Schellenberg, G. D., & Bird, T. D. (2007) · Brain

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 129

Rho‐associated protein kinase 1 (ROCK 1) is increased in Alzheimer's disease and ROCK 1 depletion reduces amyloid‐β levels in brain

Henderson, B. W., Gentry, E. G., Rush, T., Troncoso, J. C., Thambisetty, M., Montine, T. J., & Herskowitz, J. H. (2016) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 120

Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients

Takeda, S., Commins, C., DeVos, S. L., Nobuhara, C. K., Wegmann, S., Roe, A. D., Costantino, I., Fan, Z., Nicholls, S. B., Sherman, A. E., et al. (2016) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 113

Multisite assessment of NIA‐AA guidelines for the neuropathologic evaluation of Alzheimer's disease

Montine, T. J., Monsell, S. E., Beach, T. G., Bigio, E. H., Bu, Y., Cairns, N. J., Frosch, M., Henriksen, J., Kofler, J., Kukull, W. A., et al. (2016) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 113

Sex-specific genetic predictors of Alzheimer’s disease biomarkers

(ADNI), A. D. N. I., Deming, Y., The Alzheimer Disease Genetics Consortium (ADGC), Dumitrescu, L., Barnes, L. L., Thambisetty, M., Kunkle, B., Gifford, K. A., Bush, W. S., Chibnik, L. B., et al. (2018) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 110

Age-Dependent Changes in the Cerebrospinal Fluid Proteome by Slow Off-Rate Modified Aptamer Array

Baird, G. S., Nelson, S. K., Keeney, T. R., Stewart, A., Williams, S., Kraemer, S., Peskind, E. R., & Montine, T. J. (2012) · The American Journal of Pathology

Advanced Proteomics Techniques and ApplicationsCerebrospinal fluid and hydrocephalus

Cited by 110

Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity

Shie, F., Montine, K. S., Breyer, R. M., & Montine, T. J. (2005) · Glia

Neuroinflammation and Neurodegeneration MechanismsInflammatory mediators and NSAID effects

Cited by 110

White matter lesions defined by diffusion tensor imaging in older adults

Back, S. A., Kroenke, C. D., Sherman, L. S., Lawrence, G., Gong, X., Taber, E. N., Sonnen, J. A., Larson, E. B., & Montine, T. J. (2011) · Annals of Neurology

Advanced Neuroimaging Techniques and ApplicationsCerebrovascular and genetic disorders

Cited by 109

Digestion products of the PH20 hyaluronidase inhibit remyelination

Preston, M., Gong, X., Su, W., Matsumoto, S. G., Banine, F., Winkler, C., Foster, S., Xing, R., Struve, J., Dean, J., et al. (2013) · Annals of Neurology

Proteoglycans and glycosaminoglycans researchMultiple Sclerosis Research Studies

Cited by 107

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

Keene, C. D., Cudaback, E., Li, X., Montine, K. S., & Montine, T. J. (2011) · Current Opinion in Neurobiology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 103

ABCA7 frameshift deletion associated with Alzheimer disease in African Americans

Cukier, H. N., Kunkle, B. W., Vardarajan, B. N., Rolati, S., Hamilton-Nelson, K. L., Kohli, M. A., Whitehead, P. L., Dombroski, B. A., Van Booven, D., Lang, R., et al. (2016) · Neurology Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 100

Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility

Meijer, M., Agirre, E., Kabbe, M., van Tuijn, C. A., Heskol, A., Zheng, C., Mendanha Falcão, A., Bartosovic, M., Kirby, L., Calini, D., et al. (2022) · Neuron

Multiple Sclerosis Research StudiesGenomics and Chromatin Dynamics

Cited by 98

A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis

Latimer, C. S., Shively, C. A., Keene, C. D., Jorgensen, M. J., Andrews, R. N., Register, T. C., Montine, T. J., Wilson, A. M., Neth, B. J., Mintz, A., et al. (2019) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 98

Sex differences in the genetic predictors of Alzheimer’s pathology

Dumitrescu, L., Barnes, L. L., Thambisetty, M., Beecham, G., Kunkle, B., Bush, W. S., Gifford, K. A., Chibnik, L. B., Mukherjee, S., De Jager, P. L., et al. (2019) · Brain

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 93

Aggregates of Small Nuclear Ribonucleic Acids ( snRNAs ) in Alzheimer's Disease

Hales, C. M., Dammer, E. B., Diner, I., Yi, H., Seyfried, N. T., Gearing, M., Glass, J. D., Montine, T. J., Levey, A. I., & Lah, J. J. (2014) · Brain Pathology

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 89

Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE

Pulliam, J. F., Jennings, C. D., Kryscio, R. J., Davis, D. G., Wilson, D., Montine, T. J., Schmitt, F. A., & Markesbery, W. R. (2003) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 89

Putting humpty dumpty back together again: what does protein quantification mean in bottom-up proteomics?

Plubell, D. L., Käll, L., Webb-Robertson, B.-J., Bramer, L. M., Ives, A., Kelleher, N. L., Smith, L. M., Montine, T. J., Wu, C. C., & MacCoss, M. J. (2022) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and Applications

Cited by 85

Characterizing Apolipoprotein E ε4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal β-Amyloid Peptide Plaques

Monsell, S. E., Kukull, W. A., Roher, A. E., Maarouf, C. L., Serrano, G., Beach, T. G., Caselli, R. J., Montine, T. J., & Reiman, E. M. (2015) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 82

GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Shade, L. M. P., Katsumata, Y., Abner, E. L., Aung, K. Z., Claas, S. A., Qiao, Q., Heberle, B. A., Brandon, J. A., Page, M. L., Hohman, T. J., et al. (2024) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 72