Nelson, Peter S.

Circulating microRNAs as stable blood-based markers for cancer detection

Mitchell, P. S., Parkin, R. K., Kroh, E. M., Fritz, B. R., Wyman, S. K., Pogosova-Agadjanyan, E. L., Peterson, A., Noteboom, J., O'Briant, K. C., Allen, A., et al. (2008) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationExtracellular vesicles in disease

Cited by 7,969

Integrative Clinical Genomics of Advanced Prostate Cancer

Robinson, D., Van Allen, E. M., Wu, Y.-M., Schultz, N., Lonigro, R. J., Mosquera, J.-M., Montgomery, B., Taplin, M.-E., Pritchard, C. C., Attard, G., et al. (2015) · Cell

Prostate Cancer Treatment and ResearchCancer Genomics and Diagnostics

Cited by 3,645

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

Pritchard, C. C., Mateo, J., Walsh, M. F., De Sarkar, N., Abida, W., Beltran, H., Garofalo, A., Gulati, R., Carreira, S., Eeles, R., et al. (2016) · New England Journal of Medicine

BRCA gene mutations in cancerGenetic factors in colorectal cancer

Cited by 1,680

Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth

Montgomery, R. B., Mostaghel, E. A., Vessella, R., Hess, D. L., Kalhorn, T. F., Higano, C. S., True, L. D., & Nelson, P. S. (2008) · Cancer Research

Prostate Cancer Treatment and ResearchCancer, Lipids, and Metabolism

Cited by 1,419

Genomic correlates of clinical outcome in advanced prostate cancer

Abida, W., Cyrta, J., Heller, G., Prandi, D., Armenia, J., Coleman, I., Cieslik, M., Benelli, M., Robinson, D., Van Allen, E. M., et al. (2019) · Proceedings of the National Academy of Sciences

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 1,372

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

Laberge, R.-M., Sun, Y., Orjalo, A. V., Patil, C. K., Freund, A., Zhou, L., Curran, S. C., Davalos, A. R., Wilson-Edell, K. A., Liu, S., et al. (2015) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,160

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

Wang, S., Gao, J., Lei, Q., Rozengurt, N., Pritchard, C., Jiao, J., Thomas, G. V., Li, G., Roy-Burman, P., Nelson, P. S., et al. (2003) · Cancer Cell

Prostate Cancer Treatment and ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 1,109

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B

Sun, Y., Campisi, J., Higano, C., Beer, T. M., Porter, P., Coleman, I., True, L., & Nelson, P. S. (2012) · Nature Medicine

Wnt/β-catenin signaling in development and cancerProstate Cancer Treatment and Research

Cited by 793

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant.

Sun, S., Sprenger, C. C. T., Vessella, R. L., Haugk, K., Soriano, K., Mostaghel, E. A., Page, S. T., Coleman, I. M., Nguyen, H. M., Sun, H., et al. (2010) · Journal of Clinical Investigation

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 748

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

Bluemn, E. G., Coleman, I. M., Lucas, J. M., Coleman, R. T., Hernandez-Lopez, S., Tharakan, R., Bianchi-Frias, D., Dumpit, R. F., Kaipainen, A., Corella, A. N., et al. (2017) · Cancer Cell

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 744

Intraprostatic Androgens and Androgen-Regulated Gene Expression Persist after Testosterone Suppression: Therapeutic Implications for Castration-Resistant Prostate Cancer

Mostaghel, E. A., Page, S. T., Lin, D. W., Fazli, L., Coleman, I. M., True, L. D., Knudsen, B., Hess, D. L., Nelson, C. C., Matsumoto, A. M., et al. (2007) · Cancer Research

Prostate Cancer Treatment and ResearchHormonal and reproductive studies

Cited by 529

The Gene Expression Program of Prostate Fibroblast Senescence Modulates Neoplastic Epithelial Cell Proliferation through Paracrine Mechanisms

Bavik, C., Coleman, I., Dean, J. P., Knudsen, B., Plymate, S., & Nelson, P. S. (2006) · Cancer Research

Telomeres, Telomerase, and SenescenceProstate Cancer Treatment and Research

Cited by 453

Effect of Testosterone Replacement Therapy on Prostate Tissue in Men With Late-Onset Hypogonadism: A Randomized Controlled Trial

Marks, L. S., Mazer, N. A., Mostaghel, E., Hess, D. L., Dorey, F. J., Epstein, J. I., Veltri, R. W., Makarov, D. V., Partin, A. W., Bostwick, D. G., et al. (2006) · JAMA

Hormonal and reproductive studiesProstate Cancer Treatment and Research

Cited by 400

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing

Viswanathan, S. R., Ha, G., Hoff, A. M., Wala, J. A., Carrot-Zhang, J., Whelan, C. W., Haradhvala, N. J., Freeman, S. S., Reed, S. C., Rhoades, J., et al. (2018) · Cell

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 365

A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer

Chang, K.-H., Li, R., Kuri, B., Lotan, Y., Roehrborn, C. G., Liu, J., Vessella, R., Nelson, P. S., Kapur, P., Guo, X., et al. (2013) · Cell

Prostate Cancer Treatment and ResearchCancer, Lipids, and Metabolism

Cited by 312

Persistent Intraprostatic Androgen Concentrations after Medical Castration in Healthy Men

Page, S. T., Lin, D. W., Mostaghel, E. A., Hess, D. L., True, L. D., Amory, J. K., Nelson, P. S., Matsumoto, A. M., & Bremner, W. J. (2006) · The Journal of Clinical Endocrinology & Metabolism

Prostate Cancer Treatment and ResearchHormonal and reproductive studies

Cited by 229

Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors

Hovelson, D. H., McDaniel, A. S., Cani, A. K., Johnson, B., Rhodes, K., Williams, P. D., Bandla, S., Bien, G., Choppa, P., Hyland, F., et al. (2015) · Neoplasia

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

Cited by 224

Interaction of IGF signaling and the androgen receptor in prostate cancer progression.

Wu, J. D., Haugk, K., Woodke, L., Nelson, P., Coleman, I., & Plymate, S. R. (2006) · Journal of Cellular Biochemistry

Prostate Cancer Treatment and ResearchGrowth Hormone and Insulin-like Growth Factors

Cited by 188

Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer

Henzler, C., Li, Y., Yang, R., McBride, T., Ho, Y., Sprenger, C., Liu, G., Coleman, I., Lakely, B., Li, R., et al. (2016) · Nature Communications

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 173

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging

Muñoz, D. P., Yannone, S. M., Daemen, A., Sun, Y., Vakar-Lopez, F., Kawahara, M., Freund, A. M., Rodier, F., Wu, J. D., Desprez, P.-Y., et al. (2019) · JCI Insight

Telomeres, Telomerase, and SenescenceImmune Cell Function and Interaction

Cited by 162

Mismatch repair deficiency in metastatic prostate cancer: Response to PD-1 blockade and standard therapies

Graham, L. S., Montgomery, B., Cheng, H. H., Yu, E. Y., Nelson, P. S., Pritchard, C., Erickson, S., Alva, A., & Schweizer, M. T. (2020) · PLOS ONE

Prostate Cancer Treatment and ResearchCancer Immunotherapy and Biomarkers

Cited by 114

Androgen receptor (AR) expression in AR‐negative prostate cancer cells results in differential effects of DHT and IGF‐I on proliferation and AR activity between localized and metastatic tumors

Plymate, S. R., Tennant, M. K., Culp, S. H., Woodke, L., Marcelli, M., Colman, I., Nelson, P. S., Carroll, J. M., Roberts, C. T., & Ware, J. L. (2004) · The Prostate

Prostate Cancer Treatment and ResearchGrowth Hormone and Insulin-like Growth Factors

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Digital expression profiles of the prostate androgen-response program

Clegg, N., Eroglu, B., Ferguson, C., Arnold, H., Moorman, A., & Nelson, P. S. (2002) · The Journal of Steroid Biochemistry and Molecular Biology

Prostate Cancer Treatment and ResearchSperm and Testicular Function

Cited by 37

Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts

Sychev, Z. E., Day, A., Bergom, H. E., Larson, G., Ali, A., Ludwig, M., Boytim, E., Coleman, I., Corey, E., Plymate, S. R., et al. (2024) · Molecular Cancer Research

Prostate Cancer Treatment and ResearchAdvanced Proteomics Techniques and Applications

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