Lugrin, Jérôme

Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

Roger, T., Lugrin, J., Le Roy, D., Goy, G., Mombelli, M., Koessler, T., Ding, X. C., Chanson, A.-L., Reymond, M. K., Miconnet, I., et al. (2011) · Blood

Histone Deacetylase Inhibitors ResearchImmune Response and Inflammation

Cited by 341

The AIM 2 inflammasome: Sensor of pathogens and cellular perturbations

Lugrin, J., & Martinon, F. (2018) · Immunological Reviews

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 333

AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

Di Micco, A., Frera, G., Lugrin, J., Jamilloux, Y., Hsu, E.-T., Tardivel, A., De Gassart, A., Zaffalon, L., Bujisic, B., Siegert, S., et al. (2016) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersinterferon and immune responses

Cited by 143

Histone Deacetylase Inhibitors Impair Antibacterial Defenses of Macrophages

Mombelli, M., Lugrin, J., Rubino, I., Chanson, A.-L., Giddey, M., Calandra, T., & Roger, T. (2011) · The Journal of Infectious Diseases

Histone Deacetylase Inhibitors ResearchNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 89

The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock

Lugrin, J., Ciarlo, E., Santos, A., Grandmaison, G., Dos Santos, I., Le Roy, D., & Roger, T. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Sirtuins and Resveratrol in MedicineImmune Response and Inflammation

Cited by 67