Histone Deacetylase Inhibitors Impair Antibacterial Defenses of Macrophages

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Clinical and Biological Effects of Valproic Acid as a Histone Deacetylase Inhibitor on Tumor and Surrogate Tissues: Phase I/II Trial of Valproic acid and Epirubicin/FEC

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A phase II multiple dose clinical trial of histone deacetylase inhibitor ITF2357 in patients with relapsed or progressive multiple myeloma

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Potentiation of a Topoisomerase I Inhibitor, Karenitecin, by the Histone Deacetylase Inhibitor Valproic Acid in Melanoma: Translational and Phase I/II Clinical Trial

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A phase I–II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma

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Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

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Myeloid-Derived Suppressor Cells in Sepsis

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Epigenetic regulation in bacterial infections: targeting histone deacetylases

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Current trends in protein acetylation analysis

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Histone deacetylase inhibitors activate CIITA and MHC class II antigen expression in diffuse large B‐cell lymphoma

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Epigenetics in sepsis: targeting histone deacetylases.

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Regulation of Immune Responses by Histone Deacetylase Inhibitors

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Class I Histone Deacetylase Inhibitor Valproic Acid Reverses Cognitive Deficits in a Mouse Model of Septic Encephalopathy

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Macrophage Migration Inhibitory Factor Deficiency Is Associated With Impaired Killing of Gram-Negative Bacteria by Macrophages and Increased Susceptibility to Klebsiella pneumoniae Sepsis

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The Impact of Mass Spectrometry–Based Proteomics on Fundamental Discoveries in Virology

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The Role of Macrophages in the Innate Immune Response to Streptococcus pneumoniae and Staphylococcus aureus

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The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock

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Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

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Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection

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Histone Deacetylase Inhibitors as Immunomodulators in Cancer Therapeutics

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Low-dose chidamide restores immune tolerance in ITP in mice and humans

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Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages

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Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection

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The impact of histone deacetylase inhibitors on immune cells and implications for cancer therapy

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The role and mechanism of action of microbiota-derived short-chain fatty acids in neutrophils: From the activation to becoming potential biomarkers

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Impact of HDAC inhibitors on macrophage polarization to enhance innate immunity against infections

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The therapeutic potential of epigenetic manipulation during infectious diseases

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Histone Deacetylases in Herpesvirus Replication and Virus-Stimulated Host Defense

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Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4‐Derived Redox Signalling and Angiogenesis

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Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia

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Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses

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Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections

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IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns

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Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology

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The Roles of Histone H3K18 Lactylation, Acetylation, and Lactylation/Acetylation Ratio as Potential Biomarkers in the Diagnosis and Severity Assessment of Sepsis and Septic Shock

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The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE-mediated mast cell activation

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Metabolomics Analysis of Bacterial PathogenBurkholderia thailandensisand Mammalian Host Cells in Co-culture

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Epigenetic master regulators HDAC1 and HDAC5 control pathobiont Enterobacteria colonization in ileal mucosa of Crohn’s disease patients

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Screening the Impact of Sirtuin Inhibitors on Inflammatory and Innate Immune Responses of Macrophages and in a Mouse Model of Endotoxic Shock

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Mass spectrometry-based metabolomics approaches to interrogate host–microbiome interactions in mammalian systems

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Histone deacetylase inhibitors impair the host immune response against Mycobacterium tuberculosis infection

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Innate Immune Sensing ofFusarium culmorumby Mouse Dendritic Cells

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Roles of HDACs in the Responses of Innate Immune Cells and as Targets in Inflammatory Diseases

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A secreted sirtuin from Campylobacter jejuni contributes to neutrophil activation and intestinal inflammation during infection

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Design, synthesis, and biological evaluation of novel AAK1/HDACs dual inhibitors against SARS-CoV-2 entry

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Chromatin Remodelling During Host-Bacterial Pathogen Interaction

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Therapy of Infectious Diseases Using Epigenetic Approaches

Zhou, Z., Rajasingh, S., Barani, B., Samanta, S., Dawn, B., Wang, R., & Rajasingh, J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812215-0.00022-4 · Cited by 6 · see citing works

Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to Listeria monocytogenes infection

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Histone deacetylase inhibitor MS-275 augments expression of a subset of IFN-γ-regulated genes in Toxoplasma gondii-infected macrophages but does not improve parasite control

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Valproic acid restricts mast cell activation by Listeria monocytogenes

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Multi-omic Data Integration Links Deleted in Breast Cancer 1 (DBC1) Degradation to Chromatin Remodeling in Inflammatory Response

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Therapy of infectious diseases using epigenetic approaches

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Targeting histone deacetylases for bacterial infections

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Quantitative and Qualitative Distinctions between HIV-1 and SIV Reservoirs: Implications for HIV-1 Cure-Related Studies

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High-Throughput Screening on Primary Tumor-Associated Microglia and Macrophages Identifies HDAC Inhibitors as Enhancers of Phagocytosis and Potent Partners for Immunotherapy in GlioblastomaPreprint

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Development of novel benzamide class I selective lysine deacetylase inhibitors as potent anticancer agents

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Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

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Prolactin and 17β-Estradiol Are Epigenetic Regulators That Modify the Effector Response of Bovine Macrophages During Staphylococcus aureus Challenge

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A Patient-Derived Screen Identifies HDAC Inhibitors as Enhancers of Phagocytosis and Potent Immunotherapy Partners

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The histone deacetylase family in health and disease

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Utilizing Flaxseed as an Antimicrobial Alternative in Chickens: Integrative Review for Salmonella enterica and Eimeria

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Epigenetische Regulation in der Sepsis

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An Overview of Epigenetic Mechanisms in Health and Disease

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Einfluss von HDAC-Inhibitoren auf die Expression IFNγ-regulierter Gene und die Parasitenentwicklung in Toxoplasma gondii-infizierten Makrophagen

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Epigenetische Regulation in der Sepsis

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Impacto de los inhibidores de Deacetilasas de Histonas (iHDAC) sobre la funcionalidad de células NK

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Design, Synthesis, and Biological Evaluation of Novel Aak1/Hdacs Dual Inhibitors Against Sars-Cov-2 EntryPreprint

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Epigenetics and pharmacoepigenetics of bacterial infections

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Régulation de la réponse immunitaire au cours du sepsis

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Histone deacetylases, the erasers of the code

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BindingDB Entry 50016868: Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.

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Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages

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Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

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Histone deacetylase 7 coordinates innate immune defence by promoting phagocytosis, NADPH oxidase dependent reactive oxygen species production and bacterial clearance

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Targeting histone deacetylases for bacterial infections

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Histone deacetylase inhibitors impair the host immune response against Mycobacterium tuberculosis infection

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