Takeda, Kiyoshi

Toll-like receptor signalling

Akira, S., & Takeda, K. (2004) · Nature reviews. Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 8,312

A Toll-like receptor recognizes bacterial DNA

Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) · Nature

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 6,491

Toll-Like Receptors

Takeda, K., Kaisho, T., & Akira, S. (2003) · Annual Review of Immunology

Immune Response and InflammationInvertebrate Immune Response Mechanisms

Cited by 6,143

Toll-like receptors: critical proteins linking innate and acquired immunity

Akira, S., Takeda, K., & Kaisho, T. (2001) · Nature Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 4,777

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 4,554

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Atarashi, K., Tanoue, T., Shima, T., Imaoka, A., Kuwahara, T., Momose, Y., Cheng, G., Yamasaki, S., Saito, T., Ohba, Y., et al. (2011) · Science

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 3,752

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product

Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., & Akira, S. (1999) · The Journal of Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 3,374

Toll-like receptors in innate immunity

Takeda, K. (2004) · International Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 3,328

Cell Type-Specific Involvement of RIG-I in Antiviral Response

Kato, H., Sato, S., Yoneyama, M., Yamamoto, M., Uematsu, S., Matsui, K., Tsujimura, T., Takeda, K., Fujita, T., Takeuchi, O., et al. (2005) · Immunity

interferon and immune responsesImmune Response and Inflammation

Cited by 1,368

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

Takeda, K., Noguchi, K., Shi, W., Tanaka, T., Matsumoto, M., Yoshida, N., Kishimoto, T., & Akira, S. (1997) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsDevelopmental Biology and Gene Regulation

Cited by 1,323

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils

Takeda, K., Clausen, B. E., Kaisho, T., Tsujimura, T., Terada, N., Förster, I., & Akira, S. (1999) · Immunity

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 1,220

ATP drives lamina propria TH17 cell differentiation

Atarashi, K., Nishimura, J., Shima, T., Umesaki, Y., Yamamoto, M., Onoue, M., Yagita, H., Ishii, N., Evans, R., Honda, K., et al. (2008) · Nature

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 1,089

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

Herrmann, J. E., Imura, T., Song, B., Qi, J., Ao, Y., Nguyen, T. K., Korsak, R. A., Takeda, K., Akira, S., & Sofroniew, M. V. (2008) · The Journal of Neuroscience

Spinal Cord Injury ResearchCytokine Signaling Pathways and Interactions

Cited by 958

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

Yasukawa, H., Ohishi, M., Mori, H., Murakami, M., Chinen, T., Aki, D., Hanada, T., Takeda, K., Akira, S., Hoshijima, M., et al. (2003) · Nature Immunology

Cytokine Signaling Pathways and InteractionsAdipokines, Inflammation, and Metabolic Diseases

Cited by 771

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

Maeda, Y., Kurakawa, T., Umemoto, E., Motooka, D., Ito, Y., Gotoh, K., Hirota, K., Matsushita, M., Furuta, Y., Narazaki, M., et al. (2016) · Arthritis & Rheumatology

Gut microbiota and healthRheumatoid Arthritis Research and Therapies

Cited by 686

Stat3 Activation Is Responsible for IL-6-Dependent T Cell Proliferation Through Preventing Apoptosis: Generation and Characterization of T Cell-Specific Stat3-Deficient Mice

Takeda, K., Kaisho, T., Yoshida, N., Takeda, J., Kishimoto, T., & Akira, S. (1998) · The Journal of Immunology

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 584

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

Meunier, E., Dick, M. S., Dreier, R. F., Schürmann, N., Broz, D. K., Warming, S., Roose-Girma, M., Bumann, D., Kayagaki, N., Takeda, K., et al. (2014) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 485

Commensal bacteria-dependent indole production enhances epithelial barrier function in the colon

Shimada, Y., Kinoshita, M., Harada, K., Mizutani, M., Masahata, K., Kayama, H., & Takeda, K. (2013) · PLoS ONE

Gut microbiota and healthBacterial biofilms and quorum sensing

Cited by 404

A Critical Role for Stat3 Signaling in Immune Tolerance

Cheng, F., Wang, H.-W., Cuenca, A., Huang, M., Ghansah, T., Brayer, J., Kerr, W. G., Takeda, K., Akira, S., Schoenberger, S. P., et al. (2003) · Immunity

T-cell and B-cell ImmunologyCytokine Signaling Pathways and Interactions

Cited by 377

Microbial recognition by Toll-like receptors

Takeda, K., & Akira, S. (2004) · Journal of Dermatological Science

Immune Response and InflammationInflammasome and immune disorders

Cited by 285

Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells

Takahashi, D., Hoshina, N., Kabumoto, Y., Maeda, Y., Suzuki, A., Tanabe, H., Isobe, J., Yamada, T., Muroi, K., Yanagisawa, Y., et al. (2020) · EBioMedicine

T-cell and B-cell ImmunologyRheumatoid Arthritis Research and Therapies

Cited by 205

Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency

Takeda, K., Toda, K., Saibara, T., Nakagawa, M., Saika, K., Onishi, T., Sugiura, T., & Shizuta, Y. (2003) · Journal of Endocrinology

Estrogen and related hormone effectsOvarian function and disorders

Cited by 182

Host–microbiota interactions in rheumatoid arthritis

Maeda, Y., & Takeda, K. (2019) · Experimental & Molecular Medicine

Gut microbiota and healthRheumatoid Arthritis Research and Therapies

Cited by 180

The Nuclear IκB Protein IκBNS Selectively Inhibits Lipopolysaccharide-Induced IL-6 Production in Macrophages of the Colonic Lamina Propria

Hirotani, T., Lee, P. Y., Kuwata, H., Yamamoto, M., Matsumoto, M., Kawase, I., Akira, S., & Takeda, K. (2005) · The Journal of Immunology

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 167