Pennesi, Mark E.

Animal models of age related macular degeneration

Pennesi, M. E., Neuringer, M., & Courtney, R. J. (2012) · Molecular Aspects of Medicine

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 391

Lipid nanoparticles for delivery of messenger RNA to the back of the eye

Patel, S., Ryals, R. C., Weller, K. K., Pennesi, M. E., & Sahay, G. (2019) · Journal of Controlled Release

RNA Interference and Gene DeliveryAdvanced Drug Delivery Systems

Cited by 260

Gene Editing for CEP290 -Associated Retinal Degeneration

Pierce, E. A., Aleman, T. S., Jayasundera, K. T., Ashimatey, B. S., Kim, K., Rashid, A., Jaskolka, M. C., Myers, R. L., Lam, B. L., Bailey, S. T., et al. (2024) · New England Journal of Medicine

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 237

Results at 2 Years after gene therapy for RPE65-deficient leber congenital amaurosis and severe early-childhood–onset retinal dystrophy

Weleber, R. G., Pennesi, M. E., Wilson, D. J., Kaushal, S., Erker, L. R., Jensen, L., McBride, M. T., Flotte, T. R., Humphries, M., Calcedo, R., et al. (2016) · Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 218

The effects of PEGylation on LNP based mRNA delivery to the eye

Ryals, R. C., Patel, S., Acosta, C., McKinney, M., Pennesi, M. E., & Sahay, G. (2020) · PLOS ONE

RNA Interference and Gene DeliveryAdvanced Drug Delivery Systems

Cited by 194

Long-term follow-up of patients with retinitis pigmentosa receiving intraocular ciliary neurotrophic factor implants

Birch, D. G., Bennett, L. D., Duncan, J. L., Weleber, R. G., & Pennesi, M. E. (2016) · American Journal of Ophthalmology

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 112

Intravitreal Delivery of rAAV2tYF-CB-hRS1 Vector for Gene Augmentation Therapy in Patients with X-Linked Retinoschisis

Pennesi, M. E., Yang, P., Birch, D. G., Weng, C. Y., Moore, A. T., Iannaccone, A., Comander, J. I., Jayasundera, T., Chulay, J., Chulay, J., et al. (2022) · Ophthalmology Retina

Retinal Development and DisordersVirus-based gene therapy research

Cited by 71

Subretinal timrepigene emparvovec in adult men with choroideremia: a randomized phase 3 trial

MacLaren, R. E., Fischer, M. D., Gow, J. A., Lam, B. L., Sankila, E.-M. K., Girach, A., Panda, S., Yoon, D., Zhao, G., & Pennesi, M. E. (2023) · Nature Medicine

Retinal Development and DisordersVirus-based gene therapy research

Cited by 58

Assessment of visual function with cotoretigene toliparvovec in X-linked retinitis pigmentosa in the randomized XIRIUS phase 2/3 study

Lam, B. L., Pennesi, M. E., Kay, C. N., Panda, S., Gow, J. A., Zhao, G., MacLaren, R. E., MacLaren, R., Aleman, T., Birch, D., et al. (2024) · Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 51

Intraoperative optical coherence tomographic findings in patients undergoing subretinal gene therapy surgery

Vasconcelos, H. M., Lujan, B. J., Pennesi, M. E., Yang, P., & Lauer, A. K. (2020) · International Journal of Retina and Vitreous

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 39

Injection pressure levels for creating blebs during subretinal gene therapy

Scruggs, B. A., Vasconcelos, H. M., Matioli da Palma, M., Kogachi, K., Pennesi, M. E., Yang, P., Bailey, S. T., & Lauer, A. K. (2022) · Gene Therapy

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 28