Hottiger, Michael O.

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Mostoslavsky, R., Chua, K. F., Lombard, D. B., Pang, W. W., Fischer, M. R., Gellon, L., Liu, P., Mostoslavsky, G., Franco, S., Murphy, M. M., et al. (2006) · Cell

Sirtuins and Resveratrol in MedicineDNA Repair Mechanisms

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A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

Timinszky, G., Till, S., Hassa, P. O., Hothorn, M., Kustatscher, G., Nijmeijer, B., Colombelli, J., Altmeyer, M., Stelzer, E. H. K., Scheffzek, K., et al. (2009) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsDNA Repair Mechanisms

Cited by 416

Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding

Asher, G., Reinke, H., Altmeyer, M., Gutierrez-Arcelus, M., Hottiger, M. O., & Schibler, U. (2010) · Cell

Circadian rhythm and melatoninLight effects on plants

Cited by 340

A Role of Poly (ADP-Ribose) Polymerase in NF- B Transcriptional Activation

Hassa, P. O., & Hottiger, M. O. (1999) · Biological Chemistry

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 296

The peroxisome proliferator-activated receptor γ coactivator 1α/β (PGC-1) coactivators repress the transcriptional activity of NF-κB in skeletal muscle cells

Eisele, P. S., Salatino, S., Sobek, J., Hottiger, M. O., & Handschin, C. (2013) · Journal of Biological Chemistry

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 187

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats

Guetg, C., Lienemann, P., Sirri, V., Grummt, I., Hernandez‐Verdun, D., Hottiger, M. O., Fussenegger, M., & Santoro, R. (2010) · The EMBO Journal

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 184

The Sirt1 activator SRT3025 provides atheroprotection in Apoe−/− mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression

Miranda, M. X., van Tits, L. J., Lohmann, C., Arsiwala, T., Winnik, S., Tailleux, A., Stein, S., Gomes, A. P., Suri, V., Ellis, J. L., et al. (2015) · European Heart Journal

Cholesterol and Lipid MetabolismSirtuins and Resveratrol in Medicine

Cited by 153

The Two DNA Clamps Rad9/Rad1/Hus1 Complex and Proliferating Cell Nuclear Antigen Differentially Regulate Flap Endonuclease 1 Activity

Friedrich-Heineken, E., Toueille, M., Tännler, B., Bürki, C., Ferrari, E., Hottiger, M. O., & Hübscher, U. (2005) · Journal of Molecular Biology

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 76

ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high‐fat diet and impairs adipocyte function and differentiation

Erener, S., Mirsaidi, A., Hesse, M., Tiaden, A. N., Ellingsgaard, H., Kostadinova, R., Donath, M. Y., Richards, P. J., & Hottiger, M. O. (2012) · The FASEB Journal

Liver Disease Diagnosis and TreatmentAdipokines, Inflammation, and Metabolic Diseases

Cited by 48