Breda, Laura

Reactivation of developmentally silenced globin genes by forced chromatin looping

Deng, W., Rupon, J. W., Krivega, I., Breda, L., Motta, I., Jahn, K. S., Reik, A., Gregory, P. D., Rivella, S., Dean, A., et al. (2014) · Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

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Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia

Ramos, P., Casu, C., Gardenghi, S., Breda, L., Crielaard, B. J., Guy, E., Marongiu, M. F., Gupta, R., Levine, R. L., Abdel-Wahab, O., et al. (2013) · Nature Medicine

Myeloproliferative Neoplasms: Diagnosis and TreatmentErythropoietin and Anemia Treatment

Cited by 227

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

Gardenghi, S., Ramos, P., Marongiu, M. F., Melchiori, L., Breda, L., Guy, E., Muirhead, K., Rao, N., Roy, C. N., Andrews, N. C., et al. (2010) · Journal of Clinical Investigation

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 220

Decreased hepcidin mRNA expression in thalassemic mice

Adamsky, K., Weizer, O., Amariglio, N., Breda, L., Harmelin, A., Rivella, S., Rachmilewitz, E., & Rechavi, G. (2004) · British Journal of Haematology

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 108

Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers

Breda, L., Motta, I., Lourenco, S., Gemmo, C., Deng, W., Rupon, J. W., Abdulmalik, O. Y., Manwani, D., Blobel, G. A., & Rivella, S. (2016) · Blood

Hemoglobinopathies and Related DisordersVirus-based gene therapy research

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Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell‐line HepG2 induced by thalassaemic sera

Weizer‐Stern, O., Adamsky, K., Amariglio, N., Levin, C., Koren, A., Breuer, W., Rachmilewitz, E., Breda, L., Rivella, S., Ioav Cabantchik, Z., et al. (2006) · British Journal of Haematology

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 80

mRNA expression of iron regulatory genes in β-thalassemia intermedia and β-thalassemia major mouse models

Weizer-Stern, O., Adamsky, K., Amariglio, N., Rachmilewitz, E., Breda, L., Rivella, S., & Rechavi, G. (2006) · American Journal of Hematology

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 71