Philpott, Dana J.

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

Travassos, L. H., Carneiro, L. A. M., Ramjeet, M., Hussey, S., Kim, Y.-G., Magalhães, J. G., Yuan, L., Soares, F., Chea, E., Le Bourhis, L., et al. (2010) · Nature Immunology

Autophagy in Disease and TherapyImmune Response and Inflammation

Cited by 1,306

Bacterial infection causes stress-induced memory dysfunction in mice

Gareau, M. G., Wine, E., Rodrigues, D. M., Cho, J. H., Whary, M. T., Philpott, D. J., MacQueen, G., & Sherman, P. M. (2011) · Gut

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 909

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

Hezaveh, K., Shinde, R. S., Klötgen, A., Halaby, M. J., Lamorte, S., Ciudad, M. T., Quevedo, R., Neufeld, L., Liu, Z. Q., Jin, R., et al. (2022) · Immunity

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 746

NOD proteins: regulators of inflammation in health and disease

Philpott, D. J., Sorbara, M. T., Robertson, S. J., Croitoru, K., & Girardin, S. E. (2014) · Nature Reviews Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 668

Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells

Belcheva, A., Irrazabal, T., Robertson, S. J., Streutker, C., Maughan, H., Rubino, S., Moriyama, E. H., Copeland, J. K., Surendra, A., Kumar, S., et al. (2014) · Cell

Gut microbiota and healthGenetic factors in colorectal cancer

Cited by 473

NOD1 activators link innate immunity to insulin resistance

Schertzer, J. D., Tamrakar, A. K., Magalhães, J. G., Pereira, S., Bilan, P. J., Fullerton, M. D., Liu, Z., Steinberg, G. R., Giacca, A., Philpott, D. J., et al. (2011) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesImmune Response and Inflammation

Cited by 253

Commensal and Probiotic Bacteria Influence Intestinal Barrier Function and Susceptibility to Colitis in Nod1−/−;Nod2−/− Mice

Natividad, J. M. M., Petit, V., Huang, X., de Palma, G., Jury, J., Sanz, Y., Philpott, D., Garcia Rodenas, C. L., McCoy, K. D., & Verdu, E. F. (2012) · Inflammatory Bowel Diseases

Gut microbiota and healthInflammatory Bowel Disease

Cited by 139

Activation of P2X7 Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection

Lee, B. H., Hwang, D. M., Palaniyar, N., Grinstein, S., Philpott, D. J., & Hu, J. (2012) · PLoS ONE

Adenosine and Purinergic SignalingInflammasome and immune disorders

Cited by 102

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition

Lemire, P., Robertson, S. J., Maughan, H., Tattoli, I., Streutker, C. J., Platnich, J. M., Muruve, D. A., Philpott, D. J., & Girardin, S. E. (2017) · Cell Reports

Gut microbiota and healthInflammatory Bowel Disease

Cited by 98

Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner

Shutinoski, B., Hakimi, M., Harmsen, I. E., Lunn, M., Rocha, J., Lengacher, N., Zhou, Y. Y., Khan, J., Nguyen, A., Hake-Volling, Q., et al. (2019) · Science Translational Medicine

Immune Response and InflammationParkinson's Disease Mechanisms and Treatments

Cited by 96

Circulating NOD1 activators and hematopoietic NOD1 contribute to metabolic inflammation and insulin resistance

Chan, K. L., Tam, T. H., Boroumand, P., Prescott, D., Costford, S. R., Escalante, N. K., Fine, N., Tu, Y., Robertson, S. J., Prabaharan, D., et al. (2017) · Cell Reports

Adipokines, Inflammation, and Metabolic DiseasesImmune Response and Inflammation

Cited by 88

Nod-like receptors are critical for gut-brain axis signalling in mice

Pusceddu, M. M., Barboza, M., Keogh, C. E., Schneider, M., Stokes, P., Sladek, J. A., Kim, H. J. D., Torres‐Fuentes, C., Goldfild, L. R., Gillis, S. E., et al. (2019) · The Journal of Physiology

Stress Responses and CortisolGastrointestinal motility and disorders

Cited by 69

NOD2 modulates immune tolerance via the GM-CSF–dependent generation of CD103 + dendritic cells

Prescott, D., Maisonneuve, C., Yadav, J., Rubino, S. J., Girardin, S. E., & Philpott, D. J. (2020) · Proceedings of the National Academy of Sciences

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 26