Koch, Hans-Georg

Protein translocation across the inner membrane of Gram-negative bacteria: the Sec and Tat dependent protein transport pathways.

Kudva, R., Denks, K., Kuhn, P., Vogt, A., Müller, M., & Koch, H.-G. (2013) · Research in Microbiology

Bacterial Genetics and BiotechnologyDrug Transport and Resistance Mechanisms

Cited by 177

The Sec translocon mediated protein transport in prokaryotes and eukaryotes.

Denks, K., Vogt, A., Sachelaru, I., Petriman, N.-A., Kudva, R., & Koch, H.-G. (2014) · Molecular Membrane Biology

Bacterial Genetics and BiotechnologyCellular transport and secretion

Cited by 170

In Vitro Studies with Purified Components Reveal Signal Recognition Particle (SRP) and SecA/SecB as Constituents of Two Independent Protein-targeting Pathways of Escherichia coli

Koch, H.-G., Hengelage, T., Neumann-Haefelin, C., MacFarlane, J., Hoffschulte, H. K., Schimz, K.-L., Mechler, B., & Müller, M. (1999) · Molecular Biology of the Cell

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 160

Signal recognition particle-depencent protein targeting, universal to all kingdoms of life

Koch, H.-G., Moser, M., & Müller, M. (2003) · Reviews of Physiology, Biochemistry and Pharmacology

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 154

Cu Homeostasis in Bacteria: The Ins and Outs

Andrei, A., Öztürk, Y., Khalfaoui-Hassani, B., Rauch, J., Marckmann, D., Trasnea, P.-I., Daldal, F., & Koch, H.-G. (2020) · Membranes

Bacterial Genetics and BiotechnologyTrace Elements in Health

Cited by 153

FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon.

Angelini, S., Deitermann, S., & Koch, H. (2005) · The EMBO Reports

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 145

The Dynamic SecYEG Translocon

Oswald, J., Njenga, R., Natriashvili, A., Sarmah, P., & Koch, H.-G. (2021) · Frontiers in Molecular Biosciences

Bacterial Genetics and BiotechnologyHeat shock proteins research

Cited by 88

Promiscuous targeting of polytopic membrane proteins to SecYEG or YidC by the Escherichia coli signal recognition particle

Welte, T., Kudva, R., Kuhn, P., Sturm, L., Braig, D., Müller, M., Warscheid, B., Drepper, F., & Koch, H.-G. (2012) · Molecular Biology of the Cell

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 87

Co-translational protein targeting in bacteria.

Steinberg, R., Knüpffer, L., Origi, A., Asti, R., & Koch, H.-G. (2018) · FEMS Microbiology Letters

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 81

The bacterial SRP receptor, SecA and the ribosome use overlapping binding sites on the SecY translocon.

Kuhn, P., Weiche, B., Sturm, L., Sommer, E., Drepper, F., Warscheid, B., Sourjik, V., & Koch, H. (2011) · Traffic

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 76

Ligand crowding at a nascent signal sequence.

Eisner, G., Koch, H.-G., Beck, K., Brunner, J., & Müller, M. (2003) · The Journal of Cell Biology

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 69

The interaction network of the YidC insertase with the SecYEG translocon, SRP and the SRP receptor FtsY

Petriman, N.-A., Jauß, B., Hufnagel, A., Franz, L., Sachelaru, I., Drepper, F., Warscheid, B., & Koch, H.-G. (2018) · Scientific Reports

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 66

YidC and SecYEG form a heterotetrameric protein translocation channel.

Sachelaru, I., Winter, L., Knyazev, D. G., Zimmermann, M., Vogt, A., Kuttner, R., Ollinger, N., Siligan, C., Pohl, P., & Koch, H.-G. (2017) · Scientific Reports

Bacterial Genetics and BiotechnologyIon channel regulation and function

Cited by 58

A dual function for SecA in the assembly of single spanning membrane proteins in Escherichia coli.

Deitermann, S., Sprie, G. S., & Koch, H.-G. (2005) · Journal of Biological Chemistry

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 56

Noncompetitive binding of PpiD and YidC to the SecYEG translocon expands the global view on the SecYEG interactome in Escherichia coli

Jauss, B., Petriman, N.-A., Drepper, F., Franz, L., Sachelaru, I., Welte, T., Steinberg, R., Warscheid, B., & Koch, H.-G. (2019) · Journal of Biological Chemistry

Bacterial Genetics and BiotechnologyHeat shock proteins research

Cited by 43

Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor.

Mircheva, M., Boy, D., Weiche, B., Hucke, F., Graumann, P., & Koch, H.-G. (2009) · BMC Biology

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 42

Dynamic interaction of the Sec Translocon with the chaperone PpiD.

Sachelaru, I., Petriman, N.-A., Kudva, R., & Koch, H.-G. (2014) · Journal of Biological Chemistry

Bacterial Genetics and BiotechnologyHeat shock proteins research

Cited by 37

Posttranslational insertion of small membrane proteins by the bacterial signal recognition particle.

Steinberg, R., Origi, A., Natriashvili, A., Sarmah, P., Licheva, M., Walker, P. M., Kraft, C., High, S., Luirink, J., Shi, W. Q., et al. (2020) · PLOS Biology

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 34

Molecular mimicry of SecA and signal recognition particle binding to the bacterial ribosome.

Knüpffer, L., Fehrenbach, C., Denks, K., Erichsen, V., Petriman, N.-A., & Koch, H.-G. (2019) · mBio

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 28

Four phosphates at one blow: access to pentaphosphorylated magic spot nucleotides and their analysis by capillary electrophoresis.

Haas, T. M., Qiu, D., Häner, M., Angebauer, L., Ripp, A., Singh, J., Koch, H.-G., Jessen-Trefzer, C., & Jessen, H. J. (2020) · The Journal of Organic Chemistry

DNA and Nucleic Acid ChemistryOrganophosphorus compounds synthesis

Cited by 25

Ribosome-inactivation by a class of widely distributed C-tail anchored membrane proteins

Njenga, R., Boele, J., Drepper, F., Sinha, K., Marouda, E., Huesgen, P. F., Blaby-Haas, C., & Koch, H.-G. (2024) · Structure

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 13

Eeyarestatin 24 impairs SecYEG-dependent protein trafficking and inhibits growth of clinically relevant pathogens.

Steenhuis, M., Koningstein, G. M., Oswald, J., Pick, T., O’Keefe, S., Koch, H., Cavalié, A., Whitehead, R. C., Swanton, E., High, S., et al. (2021) · Molecular Microbiology

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 11