Dewhirst, Mark W.

Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

Dewhirst, M. W., Cao, Y., & Moeller, B. (2008) · Nature Reviews Cancer

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 1,022

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors

Moeller, B. J., Cao, Y., Li, C. Y., & Dewhirst, M. W. (2004) · Cancer Cell

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 996

Transport of drugs from blood vessels to tumour tissue

Dewhirst, M. W., & Secomb, T. W. (2017) · Nature Reviews Cancer

Nanoparticle-Based Drug DeliveryBarrier Structure and Function Studies

Cited by 749

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis

Sonveaux, P., Copetti, T., De Saedeleer, C. J., Végran, F., Verrax, J., Kennedy, K. M., Moon, E. J., Dhup, S., Danhier, P., Frérart, F., et al. (2012) · PLoS ONE

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 536

Drug targeting using thermally responsive polymers and local hyperthermia

Meyer, D. E., Shin, B. C., Kong, G. A., Dewhirst, M. W., & Chilkoti, A. (2001) · Journal of Controlled Release

Nanoparticle-Based Drug DeliveryUltrasound and Hyperthermia Applications

Cited by 416

Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity

Moeller, B. J., Dreher, M. R., Rabbani, Z. N., Schroeder, T., Cao, Y., Li, C. Y., & Dewhirst, M. W. (2005) · Cancer Cell

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 374

Modulation of murine breast tumor vascularity, hypoxia and chemotherapeutic response by exercise

Betof, A. S., Lascola, C. D., Weitzel, D., Landon, C., Scarbrough, P. M., Devi, G. R., Palmer, G., Jones, L. W., & Dewhirst, M. W. (2015) · JNCI: Journal of the National Cancer Institute

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 309

Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents

Braun, R. D., Lanzen, J. L., Snyder, S. A., & Dewhirst, M. W. (2001) · American Journal of Physiology-Heart and Circulatory Physiology

Cancer, Hypoxia, and MetabolismAnalytical Chemistry and Sensors

Cited by 285

Efficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical Data

Ashcraft, K. A., Peace, R. M., Betof, A. S., Dewhirst, M. W., & Jones, L. W. (2016) · Cancer Research

Cancer Cells and MetastasisExercise and Physiological Responses

Cited by 217

Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer

Kennedy, K. M., Scarbrough, P. M., Ribeiro, A., Richardson, R., Yuan, H., Sonveaux, P., Landon, C. D., Chi, J.-T., Pizzo, S., Schroeder, T., et al. (2013) · PLoS ONE

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 190

Gene Expression Profiles of Multiple Breast Cancer Phenotypes and Response to Neoadjuvant Chemotherapy

Dressman, H. K., Hans, C., Bild, A., Olson, J. A., Rosen, E., Marcom, P. K., Liotcheva, V. B., Jones, E. L., Vujaskovic, Z., Marks, J., et al. (2006) · Clinical Cancer Research

Breast Cancer Treatment StudiesGene expression and cancer classification

Cited by 163

Exercise as adjunct therapy in cancer

Ashcraft, K. A., Warner, A. B., Jones, L. W., & Dewhirst, M. W. (2019) · Seminars in Radiation Oncology

Cancer survivorship and carePhysical Activity and Health

Cited by 148

Perspectives from man’s best friend: National Academy of Medicine’s Workshop on Comparative Oncology

LeBlanc, A. K., Breen, M., Choyke, P., Dewhirst, M., Fan, T. M., Gustafson, D. L., Helman, L. J., Kastan, M. B., Knapp, D. W., Levin, W. J., et al. (2016) · Science Translational Medicine

Veterinary Oncology ResearchScience, Research, and Medicine

Cited by 147

Enhancement of Hypoxia-Induced Tumor Cell Death In vitro and Radiation Therapy In vivo by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α

Zhang, X., Kon, T., Wang, H., Li, F., Huang, Q., Rabbani, Z. N., Kirkpatrick, J. P., Vujaskovic, Z., Dewhirst, M. W., & Li, C.-Y. (2004) · Cancer Research

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 120

Tumor Cells Upregulate Normoxic HIF-1α in Response to Doxorubicin

Cao, Y., Eble, J. M., Moon, E., Yuan, H., Weitzel, D. H., Landon, C. D., Yu-Chih Nien, C., Hanna, G., Rich, J. N., Provenzale, J. M., et al. (2013) · Cancer Research

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 111

Observation of Incipient Tumor Angiogenesis That Is Independent of Hypoxia and Hypoxia Inducible Factor-1 Activation

Cao, Y., Li, C.-Y., Moeller, B. J., Yu, D., Zhao, Y., Dreher, M. R., Shan, S., & Dewhirst, M. W. (2005) · Cancer Research

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 92

Differential response to exercise in claudin-low breast cancer

Glass, O. K., Bowie, M., Fuller, J., Darr, D., Usary, J., Boss, K., Choudhury, K. R., Liu, X., Zhang, Z., Locasale, J. W., et al. (2017) · Oncotarget

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

Cited by 32