Klose, Robert J.

Genomic DNA methylation: the mark and its mediators.

Klose, R. J., & Bird, A. P. (2006) · Trends in Biochemical Sciences

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,501

JmjC-domain-containing proteins and histone demethylation

Klose, R. J., Kallin, E. M., & Zhang, Y. (2006) · Nature Reviews Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,290

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

Chowdhury, R., Yeoh, K. K., Tian, Y., Hillringhaus, L., Bagg, E. A., Rose, N. R., Leung, I. K. H., Li, X. S., Woon, E. C. Y., Yang, M., et al. (2011) · The EMBO Reports

Cancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation

Cited by 1,035

The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells

King, H. W., & Klose, R. J. (2017) · eLife

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 270

Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression

Fursova, N. A., Blackledge, N. P., Nakayama, M., Ito, S., Koseki, Y., Farcas, A. M., King, H. W., Koseki, H., & Klose, R. J. (2019) · Molecular Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 267

PRC1 catalytic activity is central to polycomb system function

Blackledge, N. P., Fursova, N. A., Kelley, J. R., Huseyin, M. K., Feldmann, A., & Klose, R. J. (2020) · Molecular Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 243

Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells

Rhodes, J. D. P., Feldmann, A., Hernández-Rodríguez, B., Díaz, N., Brown, J. M., Fursova, N. A., Blackledge, N. P., Prathapan, P., Dobrinic, P., Huseyin, M. K., et al. (2020) · Cell Reports

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 187

Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation

Hughes, A. L., Kelley, J. R., & Klose, R. J. (2020) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 139

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Huseyin, M. K., & Klose, R. J. (2021) · Nature Communications

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 69

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Huseyin, M. K., & Klose, R. J. (2020) · Nature Communications

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 69