Sahay, Gaurav

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Endocytosis of nanomedicines

Sahay, G., Alakhova, D. Y., & Kabanov, A. V. (2010) · Journal of Controlled Release

Nanoparticle-Based Drug DeliveryCellular transport and secretion

Cited by 2,181

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Sahay, G., Querbes, W., Alabi, C., Eltoukhy, A., Sarkar, S., Zurenko, C., Karagiannis, E., Love, K., Chen, D., Zoncu, R., et al. (2013) · Nature Biotechnology

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 948

In vitro and ex vivo strategies for intracellular delivery

Stewart, M. P., Sharei, A., Ding, X., Sahay, G., Langer, R., & Jensen, K. F. (2016) · Nature

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 885

Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA

Patel, S., Ashwanikumar, N., Robinson, E., Xia, Y., Mihai, C., Griffith, J. P., Hou, S., Esposito, A. A., Ketova, T., Welsher, K., et al. (2020) · Nature Communications

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 601

Self-assembled mRNA vaccines

Kim, J., Eygeris, Y., Gupta, M., & Sahay, G. (2021) · Advanced Drug Delivery Reviews

RNA Interference and Gene DeliverySARS-CoV-2 and COVID-19 Research

Cited by 514

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

Dong, Y., Love, K. T., Dorkin, J. R., Sirirungruang, S., Zhang, Y., Chen, D., Bogorad, R. L., Yin, H., Chen, Y., Vegas, A. J., et al. (2014) · Proceedings of the National Academy of Sciences

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 488

Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis

Robinson, E., MacDonald, K. D., Slaughter, K., McKinney, M., Patel, S., Sun, C., & Sahay, G. (2018) · Molecular Therapy

RNA Interference and Gene DeliveryCystic Fibrosis Research Advances

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Lipid nanoparticles for delivery of messenger RNA to the back of the eye

Patel, S., Ryals, R. C., Weller, K. K., Pennesi, M. E., & Sahay, G. (2019) · Journal of Controlled Release

RNA Interference and Gene DeliveryAdvanced Drug Delivery Systems

Cited by 260

Boosting intracellular delivery of lipid nanoparticle-encapsulated mRNA

Patel, S., Ashwanikumar, N., Robinson, E., DuRoss, A., Sun, C., Murphy-Benenato, K. E., Mihai, C., Almarsson, Ö., & Sahay, G. (2017) · Nano Letters

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

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The effects of PEGylation on LNP based mRNA delivery to the eye

Ryals, R. C., Patel, S., Acosta, C., McKinney, M., Pennesi, M. E., & Sahay, G. (2020) · PLOS ONE

RNA Interference and Gene DeliveryAdvanced Drug Delivery Systems

Cited by 194

Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

Alabi, C. A., Love, K. T., Sahay, G., Yin, H., Luly, K. M., Langer, R., & Anderson, D. G. (2013) · Proceedings of the National Academy of Sciences

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 188

Lipid nanoparticles with PEG-variant surface modifications mediate genome editing in the mouse retina

Gautam, M., Jozic, A., Su, G. L.-N., Herrera-Barrera, M., Curtis, A., Arrizabalaga, S., Tschetter, W., Ryals, R. C., & Sahay, G. (2023) · Nature Communications

RNA Interference and Gene DeliveryRetinal Development and Disorders

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Naturally Derived Membrane Lipids Impact Nanoparticle-Based Messenger RNA Delivery

Kim, J., Jozic, A., & Sahay, G. (2020) · Cellular and Molecular Bioengineering

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

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Rapid generation of circulating and mucosal decoy ACE2 using mRNA nanotherapeutics for the potential treatment of SARS-CoV-2

Kim, J., Mukherjee, A., Nelson, D., Jozic, A., & Sahay, G. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

SARS-CoV-2 and COVID-19 ResearchRNA Interference and Gene Delivery

Cited by 28

Matrix stiffness regulates lipid nanoparticle-mRNA delivery in cell-laden hydrogels

Athirasala, A., Patel, S., Menezes, P. P., Kim, J., Tahayeri, A., Sahay, G., & Bertassoni, L. E. (2022) · Nanomedicine: Nanotechnology, Biology and Medicine

RNA Interference and Gene DeliveryCellular Mechanics and Interactions

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