White, Eileen

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

Galluzzi, L., Vitale, I., Abrams, J. M., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., Dawson, T. M., Dawson, V. L., El-Deiry, W. S., Fulda, S., et al. (2012) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

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Autophagy and Metabolism

Rabinowitz, J. D., & White, E. (2010) · Science

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

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Role of autophagy in cancer

Mathew, R., Karantza-Wadsworth, V., & White, E. (2007) · Nature Reviews Cancer

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,798

Glucose feeds the TCA cycle via circulating lactate

Hui, S., Ghergurovich, J. M., Morscher, R. J., Jang, C., Teng, X., Lu, W., Esparza, L. A., Reya, T., Zhan, L., Yanxiang Guo, J., et al. (2017) · Nature

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 1,721

The role for autophagy in cancer

White, E. (2015) · Journal of Clinical Investigation

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,332

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

Guo, J. Y., Chen, H.-Y., Mathew, R., Fan, J., Strohecker, A. M., Karsli-Uzunbas, G., Kamphorst, J. J., Chen, G., Lemons, J. M. S., Karantza, V., et al. (2011) · Genes & Development

Autophagy in Disease and TherapyCancer, Hypoxia, and Metabolism

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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 1,002

Autophagy and Tumor Metabolism

Kimmelman, A. C., & White, E. (2017) · Cell Metabolism

Autophagy in Disease and TherapyCancer, Hypoxia, and Metabolism

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Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

Kamphorst, J. J., Cross, J. R., Fan, J., de Stanchina, E., Mathew, R., White, E. P., Thompson, C. B., & Rabinowitz, J. D. (2013) · Proceedings of the National Academy of Sciences

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 726

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

Guo, J. Y., Karsli-Uzunbas, G., Mathew, R., Aisner, S. C., Kamphorst, J. J., Strohecker, A. M., Chen, G., Price, S., Lu, W., Teng, X., et al. (2013) · Genes & Development

Autophagy in Disease and TherapyCancer, Lipids, and Metabolism

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Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

Liu, L., Su, X., Quinn, W. J., Hui, S., Krukenberg, K., Frederick, D. W., Redpath, P., Zhan, L., Chellappa, K., White, E., et al. (2018) · Cell Metabolism

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

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Autophagy is required for glucose homeostasis and lung tumor maintenance

Karsli-Uzunbas, G., Guo, J. Y., Price, S., Teng, X., Laddha, S. V., Khor, S., Kalaany, N. Y., Jacks, T., Chan, C. S., Rabinowitz, J. D., et al. (2014) · Cancer Discovery

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

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Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of Braf V600E–Driven Lung Tumors

Strohecker, A. M., Guo, J. Y., Karsli-Uzunbas, G., Price, S. M., Chen, G. J., Mathew, R., McMahon, M., & White, E. (2013) · Cancer Discovery

Autophagy in Disease and TherapyCancer, Hypoxia, and Metabolism

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Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia

Fan, J., Kamphorst, J. J., Mathew, R., Chung, M. K., White, E., Shlomi, T., & Rabinowitz, J. D. (2013) · Molecular Systems Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

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Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies

Stein, M., Lin, H., Jeyamohan, C., Dvorzhinski, D., Gounder, M., Bray, K., Eddy, S., Goodin, S., White, E., & DiPaola, R. S. (2010) · The Prostate

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

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Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression

Liu, Z., Chen, P., Gao, H., Gu, Y., Yang, J., Peng, H., Xu, X., Wang, H., Yang, M., Liu, X., et al. (2014) · Cancer Cell

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

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Metabolic catastrophe as a means to cancer cell death

Jin, S., DiPaola, R. S., Mathew, R., & White, E. (2007) · Journal of Cell Science

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

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Atg7 Overcomes Senescence and Promotes Growth of Braf V600E-Driven Melanoma

Xie, X., Koh, J. Y., Price, S., White, E., & Mehnert, J. M. (2015) · Cancer Discovery

Autophagy in Disease and TherapyMelanoma and MAPK Pathways

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Glutamine anabolism plays a critical role in pancreatic cancer by coupling carbon and nitrogen metabolism

Bott, A. J., Shen, J., Tonelli, C., Zhan, L., Sivaram, N., Jiang, Y.-P., Yu, X., Bhatt, V., Chiles, E., Zhong, H., et al. (2019) · Cell Reports

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

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ERK1/2‐dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl‐1 and Bcl‐xL

Ewings, K. E., Hadfield‐Moorhouse, K., Wiggins, C. M., Wickenden, J. A., Balmanno, K., Gilley, R., Degenhardt, K., White, E., & Cook, S. J. (2007) · The EMBO Journal

Cell death mechanisms and regulationCancer-related Molecular Pathways

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Coordinate Autophagy and mTOR Pathway Inhibition Enhances Cell Death in Melanoma

Xie, X., White, E. P., & Mehnert, J. M. (2013) · PLoS ONE

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

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Autophagy promotes mammalian survival by suppressing oxidative stress and p53

Yang, Y., Karsli-Uzunbas, G., Poillet-Perez, L., Sawant, A., Hu, Z. S., Zhao, Y., Moore, D., Hu, W., & White, E. (2020) · Genes & Development

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

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Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation

Jiang, M., Pabla, N., Murphy, R. F., Yang, T., Yin, X.-M., Degenhardt, K., White, E., & Dong, Z. (2007) · Journal of Biological Chemistry

Cell death mechanisms and regulationChemotherapy-induced organ toxicity mitigation

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