Seeley, William W.

Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia

Mandelli, M. L., Vilaplana, E., Brown, J. A., Hubbard, H. I., Binney, R. J., Attygalle, S., Santos-Santos, M. A., Miller, Z. A., Pakvasa, M., Henry, M. L., et al. (2016) · Brain

Dementia and Cognitive Impairment ResearchFunctional Brain Connectivity Studies

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Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

Swarup, V., Hinz, F. I., Rexach, J. E., Noguchi, K.-I., Toyoshiba, H., Oda, A., Hirai, K., Sarkar, A., Seyfried, N. T., Cheng, C., et al. (2019) · Nature Medicine

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

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Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

Pottier, C., Zhou, X., Perkerson, R. B., Baker, M., Jenkins, G. D., Serie, D. J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., et al. (2018) · The Lancet Neurology

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Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer’s disease

Lehmann, M., Madison, C. M., Ghosh, P. M., Seeley, W. W., Mormino, E., Greicius, M. D., Gorno-Tempini, M. L., Kramer, J. H., Miller, B. L., Jagust, W. J., et al. (2013) · Proceedings of the National Academy of Sciences

Functional Brain Connectivity StudiesDementia and Cognitive Impairment Research

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Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells

Fong, H., Wang, C., Knoferle, J., Walker, D., Balestra, M. E., Tong, L. M., Leung, L., Ring, K. L., Seeley, W. W., Karydas, A., et al. (2013) · Stem Cell Reports

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

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A comprehensive resource for induced pluripotent stem cells from patients with primary tauopathies

Karch, C. M., Kao, A. W., Karydas, A., Onanuga, K., Martinez, R., Argouarch, A., Wang, C., Huang, C., Sohn, P. D., Bowles, K. R., et al. (2019) · Stem Cell Reports

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

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Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage

Ranasinghe, K. G., Rankin, K. P., Lobach, I. V., Kramer, J. H., Sturm, V. E., Bettcher, B. M., Possin, K., Christine You, S., Lamarre, A. K., Shany-Ur, T., et al. (2016) · Neurology

Dementia and Cognitive Impairment ResearchHistorical and Modern Theater Studies

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The development and evolution of inhibitory neurons in primate cerebrum

Schmitz, M. T., Sandoval, K., Chen, C. P., Mostajo-Radji, M. A., Seeley, W. W., Nowakowski, T. J., Ye, C. J., Paredes, M. F., & Pollen, A. A. (2022) · Nature

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

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Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials

Staffaroni, A. M., Ljubenkov, P. A., Kornak, J., Cobigo, Y., Datta, S., Marx, G., Walters, S. M., Chiang, K., Olney, N., Elahi, F. M., et al. (2019) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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ABCA7 frameshift deletion associated with Alzheimer disease in African Americans

Cukier, H. N., Kunkle, B. W., Vardarajan, B. N., Rolati, S., Hamilton-Nelson, K. L., Kohli, M. A., Whitehead, P. L., Dombroski, B. A., Van Booven, D., Lang, R., et al. (2016) · Neurology Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture

Miller, Z. A., Sturm, V. E., Camsari, G. B., Karydas, A., Yokoyama, J. S., Grinberg, L. T., Boxer, A. L., Rosen, H. J., Rankin, K. P., Gorno-Tempini, M. L., et al. (2016) · Neurology Neuroimmunology & Neuroinflammation

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Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia

International FTD-Genomics Consortium (IFGC), Yokoyama, J. S., Karch, C. M., Fan, C. C., Bonham, L. W., Kouri, N., Ross, O. A., Rademakers, R., Kim, J., Wang, Y., et al. (2017) · Acta Neuropathologica

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

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Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis

Boland, S., Swarup, S., Ambaw, Y. A., Malia, P. C., Richards, R. C., Fischer, A. W., Singh, S., Aggarwal, G., Spina, S., Nana, A. L., et al. (2022) · Nature Communications

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

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Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations

Spina, S., Schonhaut, D. R., Boeve, B. F., Seeley, W. W., Ossenkoppele, R., O'Neil, J. P., Lazaris, A., Rosen, H. J., Boxer, A. L., Perry, D. C., et al. (2017) · Neurology

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Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression

Rexach, J. E., Polioudakis, D., Yin, A., Swarup, V., Chang, T. S., Nguyen, T., Sarkar, A., Chen, L., Huang, J., Lin, L.-C., et al. (2020) · Cell Reports

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Physiological changes in neurodegeneration—mechanistic insights and clinical utility

Ahmed, R. M., Ke, Y. D., Vucic, S., Ittner, L. M., Seeley, W., Hodges, J. R., Piguet, O., Halliday, G., & Kiernan, M. C. (2018) · Nature Reviews Neurology

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A tensor based morphometry study of longitudinal gray matter contraction in FTD

Brambati, S. M., Renda, N. C., Rankin, K. P., Rosen, H. J., Seeley, W. W., Ashburner, J., Weiner, M. W., Miller, B. L., & Gorno-Tempini, M. L. (2007) · NeuroImage

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Atrophy, hypometabolism and clinical trajectories in patients with amyloid-negative Alzheimer’s disease

Chételat, G., Ossenkoppele, R., Villemagne, V. L., Perrotin, A., Landeau, B., Mézenge, F., Jagust, W. J., Dore, V., Miller, B. L., Egret, S., et al. (2016) · Brain

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Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders

Gendron, T. F., Heckman, M. G., White, L. J., Veire, A. M., Pedraza, O., Burch, A. R., Bozoki, A. C., Dickerson, B. C., Domoto-Reilly, K., Foroud, T., et al. (2022) · Cell Reports Medicine

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Two insular regions are differentially involved in behavioral variant FTD and nonfluent/agrammatic variant PPA

Mandelli, M. L., Vitali, P., Santos, M., Henry, M., Gola, K., Rosenberg, L., Dronkers, N., Miller, B., Seeley, W. W., & Gorno-Tempini, M. L. (2016) · Cortex

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Altered topology of the functional speech production network in non-fluent/agrammatic variant of PPA

Mandelli, M. L., Welch, A. E., Vilaplana, E., Watson, C., Battistella, G., Brown, J. A., Possin, K. L., Hubbard, H. I., Miller, Z. A., Henry, M. L., et al. (2018) · Cortex

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Damage to left frontal regulatory circuits produces greater positive emotional reactivity in frontotemporal dementia

Sturm, V. E., Yokoyama, J. S., Eckart, J. A., Zakrzewski, J., Rosen, H. J., Miller, B. L., Seeley, W. W., & Levenson, R. W. (2015) · Cortex

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Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort

Seo, S. W., Ayakta, N., Grinberg, L. T., Villeneuve, S., Lehmann, M., Reed, B., DeCarli, C., Miller, B. L., Rosen, H. J., Boxer, A. L., et al. (2017) · NeuroImage: Clinical

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Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration

Mohan, S., Sampognaro, P. J., Argouarch, A. R., Maynard, J. C., Welch, M., Patwardhan, A., Courtney, E. C., Zhang, J., Mason, A., Li, K. H., et al. (2021) · Molecular Neurodegeneration

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