McKinsey, Timothy A.

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control

Chu, Z.-L., McKinsey, T. A., Liu, L., Gentry, J. J., Malim, M. H., & Ballard, D. W. (1997) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 872

Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli

Renthal, W., Maze, I., Krishnan, V., Covington, H. E., Xiao, G., Kumar, A., Russo, S. J., Graham, A., Tsankova, N., Kippin, T. E., et al. (2007) · Neuron

Histone Deacetylase Inhibitors ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 599

BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure

Duan, Q., McMahon, S., Anand, P., Shah, H., Thomas, S., Salunga, H. T., Huang, Y., Zhang, R., Sahadevan, A., Lemieux, M. E., et al. (2017) · Science Translational Medicine

Protein Degradation and InhibitorsCardiac Fibrosis and Remodeling

Cited by 262

A transcriptional switch governs fibroblast activation in heart disease

Alexanian, M., Przytycki, P. F., Micheletti, R., Padmanabhan, A., Ye, L., Travers, J. G., Gonzalez-Teran, B., Silva, A. C., Duan, Q., Ranade, S. S., et al. (2021) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 238

Therapeutic potential for HDAC inhibitors in the heart

McKinsey, T. A. (2012) · Annual Review of Pharmacology and Toxicology

Histone Deacetylase Inhibitors ResearchCardiac Fibrosis and Remodeling

Cited by 230

Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation

Stratton, M. S., Bagchi, R. A., Felisbino, M. B., Hirsch, R. A., Smith, H. E., Riching, A. S., Enyart, B. Y., Koch, K. A., Cavasin, M. A., Alexanian, M., et al. (2019) · Circulation Research

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 179

BET acetyl-lysine binding proteins control pathological cardiac hypertrophy

Spiltoir, J. I., Stratton, M. S., Cavasin, M. A., Demos-Davies, K., Reid, B. G., Qi, J., Bradner, J. E., & McKinsey, T. A. (2013) · Journal of Molecular and Cellular Cardiology

Protein Degradation and InhibitorsCardiac Fibrosis and Remodeling

Cited by 174

Chromatin remodelling drives immune cell–fibroblast communication in heart failure

Alexanian, M., Padmanabhan, A., Nishino, T., Travers, J. G., Ye, L., Pelonero, A., Lee, C. Y., Sadagopan, N., Huang, Y., Auclair, K., et al. (2024) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 140

HDAC11 suppresses the thermogenic program of adipose tissue via BRD2

Bagchi, R. A., Ferguson, B. S., Stratton, M. S., Hu, T., Cavasin, M. A., Sun, L., Lin, Y.-H., Liu, D., Londono, P., Song, K., et al. (2018) · JCI Insight

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 110

Deuterium labeling enables proteome wide turnover kinetics analysis in cell culture

Alamillo, L., Ng, D. C. M., Currie, J., Black, A., Pandi, B., Manda, V., Pavelka, J., Schaal, P., Travers, J. G., McKinsey, T. A., et al. (2025) · Cell Reports Methods

Advanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 6

Deuterium labeling enables proteome-wide turnover kinetics analysis in cell culture

Alamillo, L., Ng, D. C. M., Currie, J., Black, A., Pandi, B., Manda, V., Pavelka, J., Schaal, P., Travers, J. G., McKinsey, T. A., et al. (2025) · Cell Reports Methods

Advanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 6