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Garcinol Is an HDAC11 Inhibitor

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Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11

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Biological function and small molecule inhibitors of histone deacetylase 11

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HDAC11 Inhibition as a Potential Therapeutic Strategy for AML: Target Identification, Lead Discovery, Antitumor Potency, and Mechanism Investigation

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PWWP2B Fine‐Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex

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Protein acetylation: a novel modus of obesity regulation

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Unraveling HDAC11: Epigenetic orchestra in different diseases and structural insights for inhibitor design

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Molecular and cellular regulation of thermogenic fat

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Metabolic Vulnerabilities and Epigenetic Dysregulation in Myeloproliferative Neoplasms

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Butyrate Prevents Obesity Accompanied by HDAC9-Mediated Browning of White Adipose Tissue

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Role of the histone deacetylase family in lipid metabolism: Structural specificity and functional diversity

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SAHA induces white fat browning and rectifies metabolic dysfunctions via activation of ZFPs

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HDACs and Their Inhibitors on Post-Translational Modifications: The Regulation of Cardiovascular Disease

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Histone deacetylase functions and therapeutic implications for adult skeletal muscle metabolism

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Discovery of De Novo Macrocycle Inhibitors of Histone Deacetylase 11

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Treatment with Non-specific HDAC Inhibitors Administered after Disease Onset does not Delay Evolution in a Mouse Model of Progressive Multiple Sclerosis

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HDAC11 deficiency resists obesity by converting adipose-derived stem cells into brown adipocyte-like cells

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Transcriptome Analysis of Beet Webworm Shows That Histone Deacetylase May Affect Diapause by Regulating Juvenile Hormone

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Role of histone deacetylase on nonalcoholic fatty liver disease

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LncRNA HDAC11-AS1 Suppresses Atherosclerosis by Inhibiting HDAC11-Mediated Adropin Histone Deacetylation

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Integration of Selection Signatures and Protein Interactions Reveals NR6A1, PAPPA2, and PIK3C2B as the Promising Candidate Genes Underlying the Characteristics of Licha Black Pig

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Histone Deacetylases in Metabolism: the Known and the Unexplored

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Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy via Regulating the Expression of Citrate Cycle Genes

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Molecular epigenetics in the transition of white to brown fat

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Targeting Histone Deacetylase 11 with a Highly Selective Inhibitor for the Treatment of MASLD

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Role of Protein Lysine Acetylation in the Pathogenesis and Treatment of Obesity and Metabolic Syndrome

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Modulating the Secretome of Fat to Treat Heart Failure

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Histone modifications in cardiovascular disease initiation and progression

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HDAC11 Regulates Palmitate-induced NLRP3 Inflammasome Activation by Inducing YAP Expression in THP-1 Cells and PBMCs

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HDAC6 inhibitor ACY-1215 protects from nonalcoholic fatty liver disease via inhibiting CD14/TLR4/MyD88/MAPK/NFκB signal pathway

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Multiomics strategy-based obesity biomarkers discovery for precision medicine

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Roles of Bromodomain Extra Terminal Proteins in Metabolic Signaling and Diseases

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End binding-3 inhibitor activates regenerative program in age-related macular degeneration

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Histone modification as a potential preventative and therapeutic approach for cardiovascular disease

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Substrate-Guided Development of HDAC11-Selective Inhibitors Featuring α-Amino Amide Zinc-Binding Groups

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Transcriptional dynamics in type 2 diabetes progression is linked with circadian, thermogenic, and cellular stress in human adipose tissue

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Epigenetic determinants and non-myocardial signaling pathways contributing to heart growth and regeneration

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Emerging role of HDAC11 in skeletal muscle biology

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Emerging roles of histone deacetylases in adaptive thermogenesis

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Maintenance of thermogenic adipose tissues despite loss of the H3K27 acetyltransferases p300 or CBP

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Bromodomain and Extraterminal Domain Protein 2 in Multiple Human Diseases

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Potential roles of histone deacetylases in diabetic wound healing

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The Nonepigenetic Role for Small Molecule Histone Deacetylase Inhibitors in the Regulation of Cardiac Function

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The H3K27 acetyltransferase p300 is dispensable for thermogenic adipose tissue formation and functionPreprint

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Sexual dimorphism in offspring response to maternal high-fat diet during preconception and diverse fatty acid sources in pregnancy and lactation

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HDAC11 deficiency regulates age-related muscle decline and sarcopenia

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Nutri-epigenetics of mitochondrial function and energy homeostasis in obesity

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Epigenetic regulation by HDAC11-driven STAT3 activation promotes pro-inflammatory cytokine production and endothelial dysfunction upon bacterial infection in diabetes

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A small‑molecule HDAC/PDE modulator activates human adipocyte UCP1 and resolves inflammatory signaling

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FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

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Histone acylation in the epigenomic regulation of insulin action and metabolic disease

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FGF2 disruption enhances thermogenesis in brown and beige fat to protect against obesity and hepatic steatosisPreprint

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Obesity, histone acetylation, and insulin resistance

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Identification of Critical Molecular Pathways Induced by HDAC11 Overexpression in Cardiac Mesenchymal Stem Cells

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Epigenetic regulation of cardiometabolic disease by HDAC-BET association

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A tale of two tissues in cardiometabolic disease: HDAC11 in adipose tissue and the myocardium

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HDAC11 Deficiency Prevents High-Fat Diet-Induced Obesity and Metabolic SyndromePreprint

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Histone Deacetylase 1 (HDAC1) Negatively Regulates Thermogenic Program in Brown Adipocytes via Coordinated Regulation of Histone H3 Lysine 27 (H3K27) Deacetylation and Methylation

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