Holzbaur, Erika L.F.

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

Dixit, R., Ross, J. L., Goldman, Y. E., & Holzbaur, E. L. F. (2008) · Science

Microtubule and mitosis dynamicsAlzheimer's disease research and treatments

Cited by 1,012

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

Wong, Y. C., & Holzbaur, E. L. F. (2014) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 812

Axonal transport: cargo-specific mechanisms of motility and regulation

Maday, S., Twelvetrees, A. E., Moughamian, A. J., & Holzbaur, E. L. F. (2014) · Neuron

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 683

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

Maday, S., Wallace, K. E., & Holzbaur, E. L. F. (2012) · Journal of Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 681

Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport

Hendricks, A. G., Perlson, E., Ross, J. L., Schroeder, H. W., Tokito, M., & Holzbaur, E. L. F. (2010) · Current Biology

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 423

Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway

Maday, S., & Holzbaur, E. L. F. (2014) · Developmental Cell

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 372

Axonal transport: Driving synaptic function

Guedes-Dias, P., & Holzbaur, E. L. F. (2019) · Science

Neuroscience and Neuropharmacology ResearchMicrotubule and mitosis dynamics

Cited by 355

Autophagy in neurons

Stavoe, A. K. H., & Holzbaur, E. L. F. (2019) · Annual Review of Cell and Developmental Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 328

A reference human induced pluripotent stem cell line for large-scale collaborative studies

Pantazis, C. B., Yang, A., Lara, E., McDonough, J. A., Blauwendraat, C., Peng, L., Oguro, H., Kanaujiya, J., Zou, J., Sebesta, D., et al. (2022) · Cell Stem Cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 310

Compartment-Specific Regulation of Autophagy in Primary Neurons

Maday, S., & Holzbaur, E. L. F. (2016) · The Journal of Neuroscience

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 309

The ADP/ATP translocase drives mitophagy independent of nucleotide exchange

Hoshino, A., Wang, W.-J., Wada, S., McDermott-Roe, C., Evans, C. S., Gosis, B., Morley, M. P., Rathi, K. S., Li, J., Li, K., et al. (2019) · Nature

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 228

Kinesin-3 responds to local microtubule dynamics to target synaptic cargo delivery to the presynapse

Guedes-Dias, P., Nirschl, J. J., Abreu, N., Tokito, M. K., Janke, C., Magiera, M. M., & Holzbaur, E. L. F. (2019) · Current Biology

Microtubule and mitosis dynamicsNeuroscience and Neuropharmacology Research

Cited by 153

Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons

Evans, C. S., & Holzbaur, E. L. (2020) · eLife

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 137

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

Stavoe, A. K., Gopal, P. P., Gubas, A., Tooze, S. A., & Holzbaur, E. L. (2019) · eLife

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 82

Autophagosome assembly and cargo capture in the distal axon

Maday, S., & Holzbaur, E. L. F. (2012) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 80

Spatiotemporal dynamics of autophagy receptors in selective mitophagy

Moore, A. S., & Holzbaur, E. L. F. (2016) · Autophagy

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 41

Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes

Ayloo, S., Guedes-Dias, P., Ghiretti, A. E., & Holzbaur, E. L. F. (2017) · Molecular Biology of the Cell

Microtubule and mitosis dynamicsNerve injury and regeneration

Cited by 41

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

Dou, D., Aiken, J., & Holzbaur, E. L. F. (2023) · The Journal of Cell Biology

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 29

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

Dou, D., Aiken, J., & Holzbaur, E. L. F. (2024) · Journal of Cell Biology

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 29